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In this paper, the authors review the current medical management of MD.<\/jats:p><jats:p><jats:bold>Study Design:<\/jats:bold> Literature review.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Because of a dearth of well\u2010controlled studies, the medical management of MD remains empirical and is largely restricted to lifestyle changes, pharmacotherapy, and office\u2010based procedures. The development of transtympanic therapies represents a true therapeutic advance that has largely supplanted surgical intervention. A treatment algorithm for acute and chronic medical management is reviewed.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Despite absence of a complete understanding of MD, medical management or its natural history leads to control of vertigo in the majority of patients. Basic research is needed to understand its pathophysiology so that directed therapies can be developed and can be tested in well\u2010controlled clinical trials.<\/jats:p>","DOI":"10.1097\/mlg.0b013e31816927f0","type":"journal-article","created":{"date-parts":[[2008,5,28]],"date-time":"2008-05-28T13:51:02Z","timestamp":1211982662000},"page":"1099-1108","source":"Crossref","is-referenced-by-count":59,"title":["Medical Management Of M\u00e9ni\u00e8re's Disease"],"prefix":"10.1002","volume":"118","author":[{"given":"Daniel H.","family":"Coelho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Lalwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0194-5998(95)70102-8","volume":"113","author":"Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere's disease. 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