{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:13:58Z","timestamp":1790381638189,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T00:00:00Z","timestamp":1230854400000},"content-version":"vor","delay-in-days":154,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives\/Hypothesis:<\/jats:bold> Transoral laser microsurgery for the treatment of glottic carcinoma with anterior commissure (A\u2010com) involvement is associated with a high rate of recurrence. We prospectively evaluated the outcomes of laser microsurgery and the efficacy of second\u2010look operation in these patients.<\/jats:p><jats:p><jats:bold>Study Design:<\/jats:bold> Prospective evaluation.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Twenty\u2010seven patients with glottic carcinomas involving the A\u2010com underwent transoral laser microresection. Twenty\u2010five patients underwent second\u2010look operations 3 months after laser surgery.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> After transoral laser microresection, all patients achieved microscopic clear resection margins. Local recurrence was found in 7 of 27 patients (25.9%). Regional recurrence was found in two patients. Patients with recurrences underwent laser re\u2010resection or neck dissection; four received radiotherapy, two lost their larynxes, and three died of disease. At second\u2010look operation, early local recurrence was found in two patients, and anterior glottic webs and granulomas causing dysphonia were treated in 8 and 11 patients, respectively.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Laser microsurgery is an effective treatment modality in early glottic cancer with A\u2010com involvement but is still associated with a high rate of recurrence. Second\u2010look operation may help detect early local recurrence and treat postoperative airway or voice problems.<\/jats:p>","DOI":"10.1097\/mlg.0b013e318175338f","type":"journal-article","created":{"date-parts":[[2009,2,19]],"date-time":"2009-02-19T21:24:59Z","timestamp":1235078699000},"page":"1400-1404","source":"Crossref","is-referenced-by-count":24,"title":["The Utility of Second\u2010Look Operation After Laser Microresection of Glottic Carcinoma Involving the Anterior Commissure"],"prefix":"10.1002","volume":"118","author":[{"given":"Jong\u2010Lyel","family":"Roh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan 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