{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:32:33Z","timestamp":1778772753516,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T00:00:00Z","timestamp":1230854400000},"content-version":"vor","delay-in-days":154,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives\/Hypothesis:<\/jats:bold> The present study is a long\u2010term follow\u2010up of speech perception outcomes and cochlear implant use in three cases of meningitis that occurred after cochlear implantation.<\/jats:p><jats:p><jats:bold>Study Design:<\/jats:bold> Case series study.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Study was performed on three children implanted with different models of Clarion\u00ae devices, two of them with positioner. Recognition and comprehension were assessed via the Italian adaptation of GASP (TAP) test, and phonetically balanced bi\u2010syllabic words in open\u2010set. High resolution computed tomography scan acquisition was performed to obtain axial coronal and oblique multiplanar reconstructions of the cochlea.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Two patients were affected by enlarged cochlear acqueduct and Mondini malformation the first carrying positioner. One patient had a normal cochlea, and the positioner could have been the main cause of bacterial spread. As a consequence of meningitis the child with normal cochlea and the other with enlarged vestibular acqueduct developed cochlear ossification, increased M\u2010level and worsening of hearing outcomes. The child with Mondini malformation developed facial nerve stimulation. Contralateral implantation was performed in the first two patients.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Bacterial meningitis occurring after cochlear implantation may induce cochlear ossification, facial nerve stimulation, and permanent or temporary loss of implant use. Planned follow\u2010up with high resolution computed tomography and evaluation of M\u2010levels could be useful prognostic tools in the management of these patients.<\/jats:p>","DOI":"10.1097\/mlg.0b013e3181758154","type":"journal-article","created":{"date-parts":[[2009,2,19]],"date-time":"2009-02-19T21:28:57Z","timestamp":1235078937000},"page":"1467-1471","source":"Crossref","is-referenced-by-count":13,"title":["Follow\u2010up of Cochlear Implant Use in Patients Who Developed Bacterial Meningitis Following Cochlear Implantation"],"prefix":"10.1002","volume":"118","author":[{"given":"Patrizia","family":"Mancini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"D'Elia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ersilia","family":"Bosco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elio De","family":"Seta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Panebianco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Vergari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Filipo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"National Institute on Deafness and Other Communication Disorders.Risk of bacterial meningitis in children with cochlear implants. Available at:http:\/\/www.nidcd.nih.gov\/. Accessed August 1 2007."},{"key":"e_1_2_6_3_2","unstructured":"U. S. Food and Drug Administration.FDA public health notification: continued risk of bacterial meningitis in children with cochlear implants with a positioner beyond twenty\u2010four months post\u2010implantation. Available at:http:\/\/www.fda.gov. Accessed August 1 2007."},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200211000-00001"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200405000-00013"},{"key":"e_1_2_6_6_2","unstructured":"FDA Public Health Web Notification.Cochlear implant recipients may be at greater risk for meningitis. Updated: August 29 2002. Available at:www.fda.gov\/cdrh\/safety\/cochlear.html. 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