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The treatment regimen consists of surgical resection, radiation therapy, and chemotherapy in various, mainly stage\u2010dependent, combinations. We report two cases of primary metastatic and locally recurrent disease, which were treated with computed tomography\u2010guided interstitial high\u2010dose\u2010rate brachytherapy in palliative and curative intent, respectively. Computed tomography\u2010guided interstitial high\u2010dose\u2010rate brachytherapy should be considered as a feasible treatment option for advanced esthesioneuroblastoma<\/jats:p>","DOI":"10.1097\/mlg.0b013e3181801d05","type":"journal-article","created":{"date-parts":[[2008,10,22]],"date-time":"2008-10-22T07:09:03Z","timestamp":1224659343000},"page":"2006-2010","source":"Crossref","is-referenced-by-count":7,"title":["Interstitial High\u2010Dose\u2010Rate\u2010Brachytherapy in Advanced Esthesioneuroblastoma"],"prefix":"10.1002","volume":"118","author":[{"given":"Nikolaos","family":"Tselis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Heyd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehran","family":"Baghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Zamboglou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"410","article-title":"L\u2032esthe\u2032sioneuroepithe\u2032liome olfactif","volume":"13","author":"Berger LG","year":"1924","journal-title":"Bull Assoc Franc Etude Cancer"},{"key":"e_1_2_5_3_2","first-page":"12","article-title":"Cancer of the nasal cavity and paranasal sinuses: a series of 115 patients","volume":"36","author":"Svane\u2010Knudsen V","year":"1998","journal-title":"Rhinology"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200303000-00020"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21718"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.2.134"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s000660050031"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197603)37:3<1571::AID-CNCR2820370347>3.0.CO;2-L"},{"key":"e_1_2_5_9_2","first-page":"240","volume-title":"Atlas of Tumor Pathology","author":"Hyams VJ","year":"1988"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-005-1362-2"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199208000-00001"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(93)90457-7"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.10.010"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-005-0029-7"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.11.051"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-200202000-00002"},{"key":"e_1_2_5_17_2","first-page":"735","article-title":"Retreatment of advanced esthesioneuroblastoma with high\u2010activity I\u2010125 endocurietherapy: a case report","volume":"83","author":"Kumar PP","year":"1991","journal-title":"J Natl Med Assoc"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-007-1632-2"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.12.071"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1097%2FMLG.0b013e3181801d05","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MLG.0b013e3181801d05","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T20:19:20Z","timestamp":1696882760000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MLG.0b013e3181801d05"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["10.1097\/MLG.0b013e3181801d05"],"URL":"https:\/\/doi.org\/10.1097\/mlg.0b013e3181801d05","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}