{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T20:05:21Z","timestamp":1770235521740,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T00:00:00Z","timestamp":1230854400000},"content-version":"vor","delay-in-days":32,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective:<\/jats:bold> To examine the causative organisms in pediatric neck infections, delineate risk factors in methicillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA) pediatric neck infections, and define patient populations that should be empirically treated with MRSA sensitive antibiotics.<\/jats:p><jats:p><jats:bold>Study Design:<\/jats:bold> Retrospective chart review.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Two hundred twenty\u2010eight consecutive patients were reviewed, ages 0 to 17, presenting at a tertiary care center between 1999 and 2007 with computed tomography proven neck abscesses. Characteristics of patients with differing causative organisms were compared.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Forty\u2010eight percent of all pediatric patients' with head and neck abscesses had <jats:italic>S. aureus<\/jats:italic> as the causative organism, 29% of which were community\u2010acquired MRSA\u2014recent years showed that up to 66% of pediatric neck abscesses were MRSA culture positive. When comparing MRSA infections vs. other causative organisms multiple clinical characteristics were found which did not help to differentiate those patients at a higher risk for MRSA. Characteristics which did trend to predict an MRSA infection were few. For example, the average age of patients with MRSA was 32.5 months compared with only 16 months for the methicillin\u2010sensitive <jats:italic>S. aureus<\/jats:italic> patients. MRSA sensitivities and resistances were also examined.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> This study presents a large cohort of pediatric neck abscess patients, in which the emergence and characteristics of MRSA are shown. As community\u2010acquired MRSA infections become more prevalent, empiric antibiotic therapy must be considered. The results of this study show that the incidence of MRSA has greatly increased and clinical risk factors are not helpful in choosing those patients which may be at higher risk for an MRSA infection.<\/jats:p>","DOI":"10.1097\/mlg.0b013e318182a4fb","type":"journal-article","created":{"date-parts":[[2008,11,19]],"date-time":"2008-11-19T08:10:55Z","timestamp":1227082255000},"page":"2111-2114","source":"Crossref","is-referenced-by-count":44,"title":["Pediatric Neck Abscesses\u2014Changing Organisms and Empiric Therapies"],"prefix":"10.1002","volume":"118","author":[{"given":"Jared C.","family":"Inman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Rowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Ghostine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry","family":"Fleck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/322693"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"928","DOI":"10.3201\/eid1106.040641","article-title":"Methicillin\u2010resistant Staphylococus aureus in community\u2010acquired skin infections","volume":"11","author":"Moran GJ","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055356"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.11.1176"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.05.010"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.4.408"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200210000-00005"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.03.006"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2004.10.011"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/345436"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68853-3"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199911000-00012"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.10.1049"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.04.001"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.10.4740-4744.2003"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1097%2FMLG.0b013e318182a4fb","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MLG.0b013e318182a4fb","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T11:58:58Z","timestamp":1699963138000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MLG.0b013e318182a4fb"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1097\/MLG.0b013e318182a4fb"],"URL":"https:\/\/doi.org\/10.1097\/mlg.0b013e318182a4fb","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}