{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:46:21Z","timestamp":1768351581284,"version":"3.49.0"},"reference-count":88,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Opinion in Hematology"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1097\/moh.0000000000000048","type":"journal-article","created":{"date-parts":[[2014,5,8]],"date-time":"2014-05-08T12:15:37Z","timestamp":1399551337000},"page":"341-349","source":"Crossref","is-referenced-by-count":36,"title":["Targeting the B-cell receptor signaling pathway in B lymphoid malignancies"],"prefix":"10.1097","volume":"21","author":[{"given":"Maike","family":"Buchner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"M\u00fcschen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-14-20140605","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.cell.2004.05.014","volume":"117","author":"Kraus","year":"2004","journal-title":"Cell"},{"key":"R2-14-20140605","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/S0092-8674(00)80373-6","volume":"90","author":"Lam","year":"1997","journal-title":"Cell"},{"key":"R3-14-20140605","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1084\/jem.20090004","volume":"206","author":"Trageser","year":"2009","journal-title":"J Exp Med"},{"key":"R4-14-20140605","doi-asserted-by":"crossref","first-page":"7158","DOI":"10.1158\/0008-5472.CAN-06-0085","volume":"66","author":"Deglesne","year":"2006","journal-title":"Cancer Res"},{"key":"R5-14-20140605","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1365-2141.2005.05480.x","volume":"129","author":"Mauerer","year":"2005","journal-title":"Br J Haematol"},{"key":"R6-14-20140605","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1084\/jem.20040544","volume":"200","author":"Messmer","year":"2004","journal-title":"J Exp Med"},{"key":"R7-14-20140605","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrc1589","volume":"5","author":"Kuppers","year":"2005","journal-title":"Nat Rev Cancer"},{"key":"R8-14-20140605","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1084\/jem.184.4.1495","volume":"184","author":"Kanzler","year":"1996","journal-title":"J Exp Med"},{"key":"R9-14-20140605","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1182\/blood-2003-06-1841","volume":"102","author":"Savage","year":"2003","journal-title":"Blood"},{"key":"R10-14-20140605","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1038\/leu.2008.304","volume":"23","author":"Lu","year":"2009","journal-title":"Leukemia"},{"key":"R11-14-20140605","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1084\/jem.194.7.927","volume":"194","author":"Brauninger","year":"2001","journal-title":"J Exp Med"},{"key":"R12-14-20140605","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/cyto.990120410","volume":"12","author":"Segal","year":"1991","journal-title":"Cytometry"},{"key":"R13-14-20140605","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ccr.2012.06.012","volume":"22","author":"Sander","year":"2012","journal-title":"Cancer Cell"},{"key":"R14-14-20140605","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1146\/annurev.immunol.19.1.595","volume":"19","author":"Hardy","year":"2001","journal-title":"Annu Rev Immunol"},{"key":"R15-14-20140605","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.coi.2012.02.004","volume":"24","author":"Herzog","year":"2012","journal-title":"Curr Opin Immunol"},{"key":"R16-14-20140605","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/nri2491","volume":"9","author":"Herzog","year":"2009","journal-title":"Nat Rev Immunol"},{"key":"R17-14-20140605","doi-asserted-by":"crossref","first-page":"282","DOI":"10.4161\/sgtp.2.5.17794","volume":"2","author":"Limnander","year":"2011","journal-title":"Small GTPases"},{"key":"R18-14-20140605","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.semcdb.2007.07.009","volume":"18","author":"Gupta","year":"2007","journal-title":"Semin Cell Dev Biol"},{"key":"R19-14-20140605","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/nri3487","volume":"13","author":"Rickert","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"R20-14-20140605","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2013.00427","volume":"4","author":"Fiala","year":"2013","journal-title":"Front Immunol"},{"key":"R21-14-20140605","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nature09357","volume":"467","author":"Yang","year":"2010","journal-title":"Nature"},{"key":"R22-14-20140605","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/ni893","volume":"4","author":"Saijo","year":"2003","journal-title":"Nat Immunol"},{"key":"R23-14-20140605","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.4049\/jimmunol.155.10.4596","volume":"155","author":"Johnson","year":"1995","journal-title":"J Immunol"},{"key":"R24-14-20140605","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/338383b0","volume":"338","author":"Reth","year":"1989","journal-title":"Nature"},{"key":"R25-14-20140605","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1084\/jem.20051591","volume":"202","author":"Shinohara","year":"2005","journal-title":"J Exp Med"},{"key":"R26-14-20140605","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.molimm.2004.04.008","volume":"41","author":"Dal Porto","year":"2004","journal-title":"Mol Immunol"},{"key":"R27-14-20140605","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1126\/science.278.5340.1059","volume":"278","author":"Look","year":"1997","journal-title":"Science"},{"key":"R28-14-20140605","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/324579a0","volume":"324","author":"Sakaguchi","year":"1986","journal-title":"Nature"},{"key":"R29-14-20140605","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.ccr.2012.08.027","volume":"22","author":"Bicocca","year":"2012","journal-title":"Cancer Cell"},{"key":"R30-14-20140605","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1084\/jem.20091299","volume":"207","author":"Duy","year":"2010","journal-title":"J Exp Med"},{"key":"R31-14-20140605","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/nature05690","volume":"446","author":"Mullighan","year":"2007","journal-title":"Nature"},{"key":"R32-14-20140605","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/ni862","volume":"4","author":"Flemming","year":"2003","journal-title":"Nat Immunol"},{"key":"R33-14-20140605","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1084\/jem.20060967","volume":"203","author":"Wossning","year":"2006","journal-title":"J Exp Med"},{"key":"R34-14-20140605","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1084\/jem.20042101","volume":"201","author":"Feldhahn","year":"2005","journal-title":"J Exp Med"},{"key":"R35-14-20140605","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.4049\/jimmunol.171.11.5988","volume":"171","author":"Middendorp","year":"2003","journal-title":"J Immunol"},{"key":"R36-14-20140605","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/bcj.2014.5","volume":"4","author":"Van der Veer","year":"2014","journal-title":"Blood Cancer J"},{"key":"R37-14-20140605","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/nature11378","volume":"490","author":"Schmitz","year":"2012","journal-title":"Nature"},{"key":"R38-14-20140605","doi-asserted-by":"crossref","first-page":"4981","DOI":"10.1182\/blood-2011-07-369041","volume":"119","author":"Futosi","year":"2012","journal-title":"Blood"},{"key":"R39-14-20140605","doi-asserted-by":"crossref","first-page":"13283","DOI":"10.1073\/pnas.0702654104","volume":"104","author":"Hantschel","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"R40-14-20140605","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.ccr.2012.05.024","volume":"21","author":"Yang","year":"2012","journal-title":"Cancer Cell"},{"key":"R41-14-20140605","doi-asserted-by":"crossref","first-page":"6770","DOI":"10.1073\/pnas.89.15.6770","volume":"89","author":"Bahler","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"R42-14-20140605","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1182\/blood-2010-06-275818","volume":"117","author":"Marcucci","year":"2011","journal-title":"Blood"},{"key":"R43-14-20140605","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1182\/blood.V78.3.581.581","volume":"78","author":"Dighiero","year":"1991","journal-title":"Blood"},{"key":"R44-14-20140605","first-page":"572","volume":"70","author":"Greiner","year":"1994","journal-title":"Lab Invest"},{"key":"R45-14-20140605","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.1182\/blood-2012-05-427534","volume":"120","author":"Sachen","year":"2012","journal-title":"Blood"},{"key":"R46-14-20140605","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1172\/JCI24387","volume":"115","author":"Herve","year":"2005","journal-title":"J Clin Invest"},{"key":"R47-14-20140605","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/nature11309","volume":"489","author":"Duhren-von Minden","year":"2012","journal-title":"Nature"},{"key":"R48-14-20140605","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/nature08638","volume":"463","author":"Davis","year":"2010","journal-title":"Nature"},{"key":"R49-14-20140605","doi-asserted-by":"crossref","first-page":"5315","DOI":"10.1182\/blood-2009-02-204362","volume":"114","author":"Juszczynski","year":"2009","journal-title":"Blood"},{"key":"R50-14-20140605","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/j.1365-2036.2005.02395.x","volume":"21","author":"Gisbert","year":"2005","journal-title":"Aliment Pharmacol Ther"},{"key":"R51-14-20140605","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1136\/gutjnl-2011-300495","volume":"61","author":"Nakamura","year":"2012","journal-title":"Gut"},{"key":"R52-14-20140605","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1002\/cncr.25755","volume":"117","author":"Binder","year":"2011","journal-title":"Cancer"},{"key":"R53-14-20140605","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1182\/blood-2012-09-454439","volume":"121","author":"Binder","year":"2013","journal-title":"Blood"},{"key":"R54-14-20140605","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1182\/blood.V122.21.633.633","volume":"122","author":"Schulz","year":"2013","journal-title":"Blood"},{"key":"R55-14-20140605","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/nri2765","volume":"10","author":"Mocsai","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"R56-14-20140605","doi-asserted-by":"crossref","first-page":"5424","DOI":"10.1158\/0008-5472.CAN-08-4252","volume":"69","author":"Buchner","year":"2009","journal-title":"Cancer Res"},{"key":"R57-14-20140605","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1182\/blood-2007-07-100115","volume":"111","author":"Chen","year":"2008","journal-title":"Blood"},{"key":"R58-14-20140605","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/leu.2008.346","volume":"23","author":"Gobessi","year":"2009","journal-title":"Leukemia"},{"key":"R59-14-20140605","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1182\/blood-2009-08-236471","volume":"115","author":"Friedberg","year":"2010","journal-title":"Blood"},{"key":"R60-14-20140605","doi-asserted-by":"crossref","first-page":"4497","DOI":"10.1182\/blood-2009-07-233692","volume":"115","author":"Buchner","year":"2010","journal-title":"Blood"},{"key":"R61-14-20140605","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1124\/jpet.106.109058","volume":"319","author":"Braselmann","year":"2006","journal-title":"J Pharmacol Exp Ther"},{"key":"R62-14-20140605","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1182\/blood-2013-03-487728","volume":"122","author":"Sharman","year":"2013","journal-title":"Blood"},{"key":"R63-14-20140605","doi-asserted-by":"crossref","first-page":"6342","DOI":"10.1182\/blood-2011-02-333773","volume":"118","author":"Cheng","year":"2011","journal-title":"Blood"},{"key":"R64-14-20140605","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1124\/jpet.112.200832","volume":"344","author":"Spurgeon","year":"2013","journal-title":"J Pharmacol Exp Ther"},{"key":"R65-14-20140605","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1200\/JCO.2012.42.7906","volume":"31","author":"Advani","year":"2013","journal-title":"J Clin Oncol"},{"key":"R66-14-20140605","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1200\/JCO.2012.44.4281","volume":"31","author":"Wiestner","year":"2013","journal-title":"J Clin Oncol"},{"key":"R67-14-20140605","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S1470-2045(13)70513-8","volume":"15","author":"OBrien","year":"2014","journal-title":"Lancet Oncol"},{"key":"R68-14-20140605","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1182\/blood-2013-09-527853","volume":"123","author":"Woyach","year":"2014","journal-title":"Blood"},{"key":"R69-14-20140605","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1182\/blood-2011-11-390989","volume":"119","author":"De Rooij","year":"2012","journal-title":"Blood"},{"key":"R71-14-20140605","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1056\/NEJMoa1306220","volume":"369","author":"Wang","year":"2013","journal-title":"N Engl J Med"},{"key":"R72-14-20140605","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1182\/blood.V120.21.187.187","volume":"120","author":"Burger","year":"2012","journal-title":"Blood"},{"key":"R73-14-20140605","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1056\/NEJMoa1215637","volume":"369","author":"Byrd","year":"2013","journal-title":"N Engl J Med"},{"key":"R74-14-20140605","doi-asserted-by":"crossref","first-page":"6515","DOI":"10.1200\/jco.2012.30.15_suppl.6515","volume":"30","author":"OBrien","year":"2012","journal-title":"J Clin Oncol"},{"key":"R75-14-20140605","doi-asserted-by":"crossref","first-page":"7014","DOI":"10.1200\/jco.2013.31.15_suppl.7014","volume":"31","author":"Chang","year":"2013","journal-title":"J Clin Oncol"},{"key":"R76-14-20140605","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1182\/blood.V120.21.866.866","volume":"120","author":"Burger","year":"2012","journal-title":"Blood"},{"key":"R77-14-20140605","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1182\/blood.V120.21.560.560","volume":"120","author":"Improgo","year":"2012","journal-title":"Blood"},{"key":"R78-14-20140605","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev.immunol.22.012703.104721","volume":"22","author":"Deane","year":"2004","journal-title":"Annu Rev Immunol"},{"key":"R79-14-20140605","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1182\/blood.V92.9.3410","volume":"92","author":"Sakai","year":"1998","journal-title":"Blood"},{"key":"R80-14-20140605","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1182\/blood-2010-02-271171","volume":"116","author":"Herman","year":"2010","journal-title":"Blood"},{"key":"R81-14-20140605","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1073\/pnas.1008969108","volume":"108","author":"Kloo","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"R82-14-20140605","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1182\/blood-2006-04-015586","volume":"108","author":"Rudelius","year":"2006","journal-title":"Blood"},{"key":"R83-14-20140605","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1371\/journal.pbio.0060152","volume":"6","author":"Refaeli","year":"2008","journal-title":"PLoS Biol"},{"key":"R85-14-20140605","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1056\/NEJMoa1314583","volume":"370","author":"Gopal","year":"2014","journal-title":"N Engl J Med"},{"key":"R86-14-20140605","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1182\/blood.V122.21.677.677","volume":"122","author":"Flinn","year":"2013","journal-title":"Blood"},{"key":"R87-14-20140605","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.intimp.2010.05.014","volume":"10","author":"Hasan","year":"2010","journal-title":"Int Immunopharmacol"},{"key":"R88-14-20140605","doi-asserted-by":"crossref","first-page":"L210","DOI":"10.1152\/ajplung.90275.2008","volume":"296","author":"Lim","year":"2009","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"R89-14-20140605","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.ccr.2012.11.003","volume":"22","author":"Fontan","year":"2012","journal-title":"Cancer Cell"},{"key":"R90-14-20140605","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.ccr.2012.11.002","volume":"22","author":"Nagel","year":"2012","journal-title":"Cancer Cell"}],"container-title":["Current Opinion in Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MOH.0000000000000048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T23:28:08Z","timestamp":1689204488000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.lww.com\/00062752-201407000-00014"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":88,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1097\/moh.0000000000000048","relation":{},"ISSN":["1065-6251"],"issn-type":[{"value":"1065-6251","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}