{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:56:15Z","timestamp":1783144575567,"version":"3.54.6"},"reference-count":70,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1097\/mol.0000000000000025","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T09:07:46Z","timestamp":1383296866000},"page":"518-524","source":"Crossref","is-referenced-by-count":17,"title":["Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis"],"prefix":"10.1097","volume":"24","author":[{"given":"Esther","family":"Smeets","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svenja","family":"Meiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Lutgens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20211004","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.clim.2009.07.002","article-title":"Adaptive immunity and atherosclerosis.","volume":"134","author":"Andersson","year":"2010","journal-title":"Clin Immunol"},{"key":"R2-10-20211004","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1172\/JCI63108","article-title":"Adaptive immunity in atherogenesis: new insights and therapeutic approaches.","volume":"123","author":"Lichtman","year":"2013","journal-title":"J Clin Invest"},{"key":"R3-10-20211004","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1161\/ATVBAHA.108.179705","article-title":"Inflammation in atherosclerosis.","volume":"32","author":"Libby","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R4-10-20211004","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1161\/01.CIR.102.24.2919","article-title":"Transfer of CD4() T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice.","volume":"102","author":"Zhou","year":"2000","journal-title":"Circulation"},{"key":"R5-10-20211004","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/S0002-9440(10)63252-X","article-title":"Deleting TCR alpha beta or CD4 T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice.","volume":"165","author":"Elhage","year":"2004","journal-title":"Am J Pathol"},{"key":"R6-10-20211004","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1161\/ATVBAHA.109.202671","article-title":"Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis.","volume":"30","author":"Klingenberg","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R7-10-20211004","doi-asserted-by":"crossref","first-page":"226","DOI":"10.3389\/fphys.2012.00226","article-title":"Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis.","volume":"3","author":"Weih","year":"2012","journal-title":"Front Physiol"},{"key":"R8-10-20211004","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1161\/CIRCRESAHA.111.248542","article-title":"B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions.","volume":"109","author":"Kyaw","year":"2011","journal-title":"Circ Res"},{"key":"R9-10-20211004","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1172\/JCI36800","article-title":"Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans.","volume":"119","author":"Chou","year":"2009","journal-title":"J Clin Invest"},{"key":"R10-10-20211004","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1084\/jem.20100155","article-title":"B cell depletion reduces the development of atherosclerosis in mice.","volume":"207","author":"Ait-Oufella","year":"2010","journal-title":"J Exp Med"},{"key":"R11-10-20211004","doi-asserted-by":"crossref","first-page":"4410","DOI":"10.4049\/jimmunol.1000033","article-title":"Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis.","volume":"185","author":"Kyaw","year":"2010","journal-title":"J Immunol"},{"key":"R12-10-20211004","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.atherosclerosis.2010.11.024","article-title":"OxLDL-IgG immune complexes induce expression and secretion of proatherogenic cytokines by cultured human mast cells.","volume":"214","author":"Lappalainen","year":"2011","journal-title":"Atherosclerosis"},{"key":"R13-10-20211004","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/eurheartj\/ehq521","article-title":"Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability.","volume":"32","author":"Montecucco","year":"2011","journal-title":"Eur Heart J"},{"key":"R14-10-20211004","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3389\/fimmu.2012.00373","article-title":"B cell subsets in atherosclerosis.","volume":"3","author":"Perry","year":"2012","journal-title":"Front Immunol"},{"key":"R15-10-20211004","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1146\/annurev.immunol.021908.132706","article-title":"T cell activation.","volume":"27","author":"Smith-Garvin","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"R16-10-20211004","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1160\/TH09-01-0029","article-title":"The multifunctionality of CD40L and its receptor CD40 in atherosclerosis.","volume":"102","author":"Lievens","year":"2009","journal-title":"Thromb Haemost"},{"key":"R17-10-20211004","doi-asserted-by":"crossref","first-page":"464532","DOI":"10.1155\/2012\/464532","article-title":"The role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis.","volume":"2012","author":"Antunes","year":"2012","journal-title":"J Biomed Biotechnol"},{"key":"R18-10-20211004","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1038\/15271","article-title":"Requirement for CD154 in the progression of atherosclerosis.","volume":"5","author":"Lutgens","year":"1999","journal-title":"Nat Med"},{"key":"R19-10-20211004","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/28204","article-title":"Reduction of atherosclerosis in mice by inhibition of CD40 signalling.","volume":"394","author":"Mach","year":"1998","journal-title":"Nature"},{"key":"R20-10-20211004","doi-asserted-by":"crossref","first-page":"7458","DOI":"10.1073\/pnas.97.13.7458","article-title":"Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice.","volume":"97","author":"Schonbeck","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R21-10-20211004","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1084\/jem.187.11.1849","article-title":"CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand.","volume":"187","author":"Saoulli","year":"1998","journal-title":"J Exp Med"},{"key":"R22-10-20211004","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1073\/pnas.94.5.1931","article-title":"Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis.","volume":"94","author":"Mach","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R23-10-20211004","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1161\/01.CIR.100.6.614","article-title":"Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes.","volume":"100","author":"Aukrust","year":"1999","journal-title":"Circulation"},{"key":"R24-10-20211004","doi-asserted-by":"crossref","first-page":"E55","DOI":"10.1002\/clc.20667","article-title":"The relationship between CD40 gene polymorphism and unstable coronary atherosclerotic plaques.","volume":"33","author":"Wang","year":"2010","journal-title":"Clin Cardiol"},{"key":"R25-10-20211004","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1161\/CIRCULATIONAHA.107.699173","article-title":"CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice.","volume":"117","author":"Olofsson","year":"2008","journal-title":"Circulation"},{"key":"R26-10-20211004","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.cca.2009.12.011","article-title":"Enhanced levels of soluble and membrane-bound CD137 levels in patients with acute coronary syndromes.","volume":"411","author":"Dongming","year":"2010","journal-title":"Clin Chim Acta"},{"key":"R27-10-20211004","doi-asserted-by":"crossref","first-page":"193","DOI":"10.6061\/clinics\/2013(02)OA12","article-title":"Clinical implications of elevated serum soluble CD137 levels in patients with acute coronary syndrome.","volume":"68","author":"Yan","year":"2013","journal-title":"Clinics (Sao Paulo)"},{"key":"R28-10-20211004","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1159\/000314772","article-title":"CD70-driven chronic immune activation is protective against atherosclerosis.","volume":"2","author":"van Olffen","year":"2010","journal-title":"J Innate Immun"},{"key":"R29-10-20211004","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0021-9150(97)00135-4","article-title":"Costimulatory molecules in human atherosclerotic plaques: an indication of antigen specific T lymphocyte activation.","volume":"133","author":"de Boer","year":"1997","journal-title":"Atherosclerosis"},{"key":"R30-10-20211004","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/ng1524","article-title":"Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.","volume":"37","author":"Wang","year":"2005","journal-title":"Nat Genet"},{"key":"R31-10-20211004","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/cvr\/cvq211","article-title":"OX40 ligand plays an important role in the development of atherosclerosis through vasa vasorum neovascularization.","volume":"88","author":"Nakano","year":"2010","journal-title":"Cardiovasc Res"},{"key":"R32-10-20211004","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1161\/01.ATV.0000251007.07648.81","article-title":"Interruption of the Tnfrsf4Tnfsf4(OX40OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.","volume":"27","author":"van Wanrooij","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R33-10-20211004","doi-asserted-by":"crossref","first-page":"e60854","DOI":"10.1371\/journal.pone.0060854","article-title":"OX40-OX40L interaction promotes proliferation and activation of lymphocytes via NFATc1 in ApoE-deficient mice.","volume":"8","author":"Yan","year":"2013","journal-title":"PLoS One"},{"key":"R34-10-20211004","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-2567.2006.02453.x","article-title":"Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques.","volume":"119","author":"Kim","year":"2006","journal-title":"Immunology"},{"key":"R35-10-20211004","doi-asserted-by":"crossref","first-page":"e779","DOI":"10.1371\/journal.pone.0000779","article-title":"Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions.","volume":"2","author":"de Boer","year":"2007","journal-title":"PLoS One"},{"key":"R36-10-20211004","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1161\/ATVBAHA.112.300509","article-title":"Interference of the CD30-CD30L pathway reduces atherosclerosis development.","volume":"32","author":"Foks","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R37-10-20211004","first-page":"237","article-title":"In vitro soluble CD30 levels in patients with chronic stable coronary artery disease.","volume":"10","author":"Mahmoudi","year":"2011","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"R38-10-20211004","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.atherosclerosis.2011.01.010","article-title":"TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice.","volume":"215","author":"Watt","year":"2011","journal-title":"Atherosclerosis"},{"key":"R39-10-20211004","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1007\/s00125-011-2308-0","article-title":"TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe -- mice.","volume":"54","author":"Di Bartolo","year":"2011","journal-title":"Diabetologia"},{"key":"R40-10-20211004","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.jacc.2004.12.065","article-title":"The involvement of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in atherosclerosis.","volume":"45","author":"Michowitz","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"R41-10-20211004","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/j.bcp.2007.10.020","article-title":"Expression, regulation and function of trail in atherosclerosis.","volume":"75","author":"Kavurma","year":"2008","journal-title":"Biochem Pharmacol"},{"key":"R43-10-20211004","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1161\/ATVBAHA.107.140566","article-title":"TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.","volume":"27","author":"Zirlik","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R44-10-20211004","doi-asserted-by":"crossref","first-page":"22414","DOI":"10.1074\/jbc.274.32.22414","article-title":"Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.","volume":"274","author":"Leo","year":"1999","journal-title":"J Biol Chem"},{"key":"R45-10-20211004","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1161\/CIRCULATIONAHA.112.100339","article-title":"Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of Toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis.","volume":"126","author":"Polykratis","year":"2012","journal-title":"Circulation"},{"key":"R46-10-20211004","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1161\/CIRCULATIONAHA.109.895037","article-title":"Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall.","volume":"121","author":"Missiou","year":"2010","journal-title":"Circulation"},{"key":"R47-10-20211004","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1161\/CIRCRESAHA.110.219295","article-title":"TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.","volume":"107","author":"Missiou","year":"2010","journal-title":"Circ Res"},{"key":"R48-10-20211004","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1073\/pnas.0500187102","article-title":"TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF25-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.","volume":"102","author":"Hauer","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R49-10-20211004","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1172\/JCI200113620","article-title":"Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation.","volume":"108","author":"Urbich","year":"2001","journal-title":"J Clin Invest"},{"key":"R50-10-20211004","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1161\/01.CIR.0000089373.49941.C4","article-title":"Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo.","volume":"108","author":"Yamawaki","year":"2003","journal-title":"Circulation"},{"key":"R51-10-20211004","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3109\/07853890.2010.546362","article-title":"The CD40-CD40L system in cardiovascular disease.","volume":"43","author":"Pamukcu","year":"2011","journal-title":"Ann Med"},{"key":"R52-10-20211004","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1002\/eji.200323729","article-title":"Distinct contributions of different CD40 TRAF binding sites to CD154-induced dendritic cell maturation and IL-12 secretion.","volume":"33","author":"Mackey","year":"2003","journal-title":"Eur J Immunol"},{"key":"R53-10-20211004","doi-asserted-by":"crossref","first-page":"e23239","DOI":"10.1371\/journal.pone.0023239","article-title":"CD40 is essential in the upregulation of TRAF proteins and NF-kappaB-dependent proinflammatory gene expression after arterial injury.","volume":"6","author":"Song","year":"2011","journal-title":"PLoS One"},{"key":"R54-10-20211004","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1161\/01.ATV.0000161420.55482.ef","article-title":"Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cells.","volume":"25","author":"Bavendiek","year":"2005","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R55-10-20211004","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1084\/jem.20091293","article-title":"Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.","volume":"207","author":"Lutgens","year":"2010","journal-title":"J Exp Med"},{"key":"R56-10-20211004","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1161\/CIRCULATIONAHA.106.683201","article-title":"CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.","volume":"115","author":"Zirlik","year":"2007","journal-title":"Circulation"},{"key":"R57-10-20211004","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1155\/2006\/427174","article-title":"Serum levels of platelet released CD40 ligand are increased in early onset occlusive carotid artery disease.","volume":"22","author":"Balla","year":"2006","journal-title":"Dis Markers"},{"key":"R58-10-20211004","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1161\/01.CIR.0000028962.04520.01","article-title":"Platelet-derived CD40L: the switch-hitting player of cardiovascular disease.","volume":"106","author":"Andre","year":"2002","journal-title":"Circulation"},{"key":"R59-10-20211004","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1189\/jlb.0610351","article-title":"Role of CD27CD70 pathway of activation in immunity and tolerance.","volume":"89","author":"Denoeud","year":"2011","journal-title":"J Leukoc Biol"},{"key":"R60-10-20211004","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S1074-7613(01)00236-9","article-title":"Constitutive CD27CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion.","volume":"15","author":"Arens","year":"2001","journal-title":"Immunity"},{"key":"R61-10-20211004","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.4049\/jimmunol.173.6.3901","article-title":"Signaling through CD70 regulates B cell activation and IgG production.","volume":"173","author":"Arens","year":"2004","journal-title":"J Immunol"},{"key":"R62-10-20211004","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4049\/jimmunol.1202353","article-title":"CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus.","volume":"190","author":"Munitic","year":"2013","journal-title":"J Immunol"},{"key":"R63-10-20211004","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.immuni.2012.09.009","article-title":"The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity.","volume":"38","author":"Coquet","year":"2013","journal-title":"Immunity"},{"key":"R64-10-20211004","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1172\/JCI63891","article-title":"Depletion of FOXP3 regulatory T cells promotes hypercholesterolemia and atherosclerosis.","volume":"123","author":"Klingenberg","year":"2013","journal-title":"J Clin Invest"},{"key":"R65-10-20211004","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1084\/jem.20112061","article-title":"Epithelial and dendritic cells in the thymic medulla promote CD4Foxp3 regulatory T cell development via the CD27-CD70 pathway.","volume":"210","author":"Coquet","year":"2013","journal-title":"J Exp Med"},{"key":"R66-10-20211004","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1182\/blood-2007-01-070748","article-title":"OX40 costimulation turns off Foxp3 Tregs.","volume":"110","author":"Vu","year":"2007","journal-title":"Blood"},{"key":"R67-10-20211004","doi-asserted-by":"crossref","first-page":"7240","DOI":"10.4049\/jimmunol.180.11.7240","article-title":"Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.","volume":"180","author":"Song","year":"2008","journal-title":"J Immunol"},{"key":"R68-10-20211004","doi-asserted-by":"crossref","first-page":"3547","DOI":"10.4049\/jimmunol.1003156","article-title":"OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling.","volume":"186","author":"So","year":"2011","journal-title":"J Immunol"},{"key":"R69-10-20211004","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1128\/MCB.18.1.558","article-title":"4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB.","volume":"18","author":"Arch","year":"1998","journal-title":"Mol Cell Biol"},{"key":"R70-10-20211004","doi-asserted-by":"crossref","first-page":"8093","DOI":"10.4049\/jimmunol.180.12.8093","article-title":"ERK-dependent Bim modulation downstream of the 4-1BB-TRAF1 signaling axis is a critical mediator of CD8 T cell survival in vivo.","volume":"180","author":"Sabbagh","year":"2008","journal-title":"J Immunol"},{"key":"R71-10-20211004","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/CIRCULATIONAHA.109.882704","article-title":"CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.","volume":"121","author":"Jeon","year":"2010","journal-title":"Circulation"}],"container-title":["Current Opinion in Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00041433-201312000-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T08:06:11Z","timestamp":1633507571000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00041433-201312000-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":70,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/mol.0000000000000025","relation":{},"ISSN":["0957-9672"],"issn-type":[{"value":"0957-9672","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}