{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:18:01Z","timestamp":1790983081149,"version":"4.1.0"},"reference-count":68,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1097\/mol.0b013e3282f64542","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T11:20:12Z","timestamp":1236252012000},"page":"106-112","source":"Crossref","is-referenced-by-count":21,"title":["Single gene contributions: genetic variants of peroxisome proliferator-activated receptor (isoforms \u03b1, \u03b2\/\u03b4 and \u03b3) and mechanisms of dyslipidemias"],"prefix":"10.1097","volume":"19","author":[{"given":"Eu Leong","family":"Yong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei Hui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-3-20210205","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1126\/science.1142382","article-title":"A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants","volume":"316","author":"Scott","year":"2007","journal-title":"Science"},{"key":"R2-3-20210205","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1124\/pr.58.4.2","article-title":"Overview of nomenclature of nuclear receptors","volume":"58","author":"Germain","year":"2006","journal-title":"Pharmacol Rev"},{"key":"R3-3-20210205","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00018-003-3216-3","article-title":"Peroxisome proliferator-activated receptor alpha target genes","volume":"61","author":"Mandard","year":"2004","journal-title":"Cell Mol Life Sci"},{"key":"R4-3-20210205","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1172\/JCI28003","article-title":"PPAR gamma and human metabolic disease","volume":"116","author":"Semple","year":"2006","journal-title":"J Clin Invest"},{"key":"R5-3-20210205","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1172\/JCI119424","article-title":"Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids","volume":"99","author":"Vidal-Puig","year":"1997","journal-title":"J Clin Invest"},{"key":"R6-3-20210205","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/47254","article-title":"Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension","volume":"402","author":"Barroso","year":"1999","journal-title":"Nature"},{"key":"R7-3-20210205","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1210\/en.2004-1405","article-title":"A dominant negative human peroxisome proliferator-activated receptor (PPAR)\u03b1 is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms","volume":"146","author":"Semple","year":"2005","journal-title":"Endocrinology"},{"key":"R8-3-20210205","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.2337\/db06-0389","article-title":"Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice","volume":"55","author":"Gray","year":"2006","journal-title":"Diabetes"},{"key":"R9-3-20210205","doi-asserted-by":"crossref","first-page":"5708","DOI":"10.1210\/en.2006-0684","article-title":"Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPAR\u03b3) function","volume":"147","author":"Gray","year":"2006","journal-title":"Endocrinology"},{"key":"R10-3-20210205","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.cmet.2006.09.003","article-title":"Non-DNA binding, dominant-negative, human PPAR\u03b3 mutations cause lipodystrophic insulin resistance","volume":"4","author":"Agostini","year":"2006","journal-title":"Cell Metab"},{"key":"R11-3-20210205","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1210\/me.2006-0401","article-title":"Altered promoter recycling rates contribute to dominant-negative activity of human peroxisome proliferator-activated receptor-gamma mutations associated with diabetes","volume":"21","author":"Li","year":"2007","journal-title":"Mol Endocrinol"},{"key":"R12-3-20210205","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1210\/jc.2006-1807","article-title":"Familial partial lipodystrophy phenotype resulting from a single-base mutation in deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma","volume":"92","author":"Monajemi","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"R13-3-20210205","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1210\/jc.2005-2624","article-title":"Peroxisome proliferator-activated receptor-gamma C190S mutation causes partial lipodystrophy","volume":"92","author":"Ludtke","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"R14-3-20210205","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2350-7-3","article-title":"Peroxisomal proliferator-activated receptor-gamma deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3)","volume":"7","author":"Francis","year":"2006","journal-title":"BMC Med Genet"},{"key":"R15-3-20210205","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1136\/jmg.2007.050567","article-title":"New PPARG mutation leads to lipodystrophy and loss of protein function that is partially restored by a synthetic ligand","volume":"44","author":"Ludtke","year":"2007","journal-title":"J Med Genet"},{"key":"R16-3-20210205","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1210\/me.2006-0485","article-title":"Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy","volume":"21","author":"Jeninga","year":"2007","journal-title":"Mol Endocrinol"},{"key":"R17-3-20210205","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.2337\/dc06-0513","article-title":"Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with prediabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals","volume":"29","author":"Tonjes","year":"2006","journal-title":"Diabetes Care"},{"key":"R18-3-20210205","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/clc.4960290706","article-title":"Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population","volume":"29","author":"Li","year":"2006","journal-title":"Clin Cardiol"},{"key":"R19-3-20210205","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.neulet.2006.08.024","article-title":"Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism is associated with reduced risk for ischemic stroke with type 2 diabetes","volume":"410","author":"Lee","year":"2006","journal-title":"Neurosci Lett"},{"key":"R20-3-20210205","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/sj.jhh.1002040","article-title":"Association between the Pro12Ala variant of the peroxisome proliferator-activated receptor-gamma2 gene and increased 24-h diastolic blood pressure in obese patients with type II diabetes","volume":"20","author":"Stefanski","year":"2006","journal-title":"J Hum Hypertens"},{"key":"R21-3-20210205","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1373\/clinchem.2006.069690","article-title":"Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in non-E3\/E3 patients with the metabolic syndrome","volume":"52","author":"Cardona","year":"2006","journal-title":"Clin Chem"},{"key":"R22-3-20210205","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1210\/jc.2006-0590","article-title":"The Pro12Ala variant of the PPARG gene is a risk factor for peroxisome proliferator-activated receptor-gamma\/alpha agonist-induced edema in type 2 diabetic patients","volume":"91","author":"Hansen","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"R23-3-20210205","doi-asserted-by":"crossref","first-page":"494","DOI":"10.2337\/db06-0915","article-title":"A possible role for the PPARG Pro12Ala polymorphism in preterm birth","volume":"56","author":"Meirhaeghe","year":"2007","journal-title":"Diabetes"},{"key":"R24-3-20210205","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1203\/01.pdr.0000238259.41560.00","article-title":"PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity","volume":"60","author":"Scaglioni","year":"2006","journal-title":"Pediatr Res"},{"key":"R25-3-20210205","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1038\/oby.2006.218","article-title":"Fetal and maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala does not influence birth weight","volume":"14","author":"Pfab","year":"2006","journal-title":"Obesity (Silver Spring)"},{"key":"R26-3-20210205","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.2337\/dc05-1993","article-title":"The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose\/insulin metabolism interact with prenatal exposure to famine","volume":"29","author":"de Rooij","year":"2006","journal-title":"Diabetes Care"},{"key":"R27-3-20210205","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1016\/j.fertnstert.2005.10.047","article-title":"Polymorphisms of the peroxisome proliferator-activated receptor-gamma and its coactivator-1alpha genes in Chinese women with polycystic ovary syndrome","volume":"85","author":"Wang","year":"2006","journal-title":"Fertil Steril"},{"key":"R28-3-20210205","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.fertnstert.2006.10.006","article-title":"Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome","volume":"87","author":"Antoine","year":"2007","journal-title":"Fertil Steril"},{"key":"R29-3-20210205","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1038\/oby.2007.617","article-title":"Heterogeneous effect of peroxisome proliferator-activated receptor gamma2 Ala12 variant on type 2 diabetes risk","volume":"15","author":"Ludovico","year":"2007","journal-title":"Obesity (Silver Spring)"},{"key":"R30-3-20210205","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.2337\/diabetes.55.04.06.db05-0676","article-title":"The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) study","volume":"55","author":"Jaziri","year":"2006","journal-title":"Diabetes"},{"key":"R31-3-20210205","first-page":"99","article-title":"Association of beta3 adrenergic receptor and peroxisome proliferator-activated receptor gamma 2 polymorphisms with insulin sensitivity: a twin study","volume":"20","author":"Chen","year":"2007","journal-title":"Biomed Environ Sci"},{"key":"R32-3-20210205","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1017\/BJN20061901","article-title":"Weight regain after slimming induced by an energy-restricted diet depends on interleukin-6 and peroxisome-proliferator-activated-receptor-gamma2 gene polymorphisms","volume":"96","author":"Goyenechea","year":"2006","journal-title":"Br J Nutr"},{"key":"R33-3-20210205","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1038\/oby.2007.630","article-title":"Peroxisome proliferator-activated receptor gamma 2 and acyl-CoA synthetase 5 polymorphisms influence diet response","volume":"15","author":"Adamo","year":"2007","journal-title":"Obesity (Silver Spring)"},{"key":"R34-3-20210205","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1038\/oby.2005.262","article-title":"ACDC\/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity","volume":"13","author":"Tanko","year":"2005","journal-title":"Obes Res"},{"key":"R35-3-20210205","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.clinbiochem.2005.10.002","article-title":"Improved prediction of early-onset coronary artery disease using APOE epsilon4, BChE-K, PPARgamma2 Pro12 and ENOS T-786C in a polygenic model","volume":"39","author":"Nassar","year":"2006","journal-title":"Clin Biochem"},{"key":"R36-3-20210205","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.metabol.2006.10.022","article-title":"Association of the peroxisome proliferator-activated receptor gamma gene with type 2 diabetes mellitus varies by physical activity among non-Hispanic whites from Colorado","volume":"56","author":"Nelson","year":"2007","journal-title":"Metabolism"},{"key":"R37-3-20210205","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.physbeh.2006.05.028","article-title":"Energy balance and food intake: the role of PPARgamma gene polymorphisms","volume":"88","author":"Cecil","year":"2006","journal-title":"Physiol Behav"},{"key":"R38-3-20210205","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1007\/s00125-007-0664-6","article-title":"The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention","volume":"50","author":"Rittig","year":"2007","journal-title":"Diabetologia"},{"key":"R39-3-20210205","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1093\/jn\/136.9.2325","article-title":"Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid","volume":"136","author":"Soriguer","year":"2006","journal-title":"J Nutr"},{"key":"R41-3-20210205","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S0026-0495(03)00071-4","article-title":"Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala","volume":"52","author":"Tschritter","year":"2003","journal-title":"Metabolism"},{"key":"R42-3-20210205","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/01.fpc.0000220565.90466.79","article-title":"Association of V227A PPARalpha polymorphism with altered serum biochemistry and alcohol drinking in Japanese men","volume":"16","author":"Naito","year":"2006","journal-title":"Pharmacogenet Genomics"},{"key":"R43-3-20210205","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1471-2350-8-55","article-title":"PPAR alpha L162V underlies variation in serum triglycerides and subcutaneous fat volume in young males","volume":"8","author":"Uthurralt","year":"2007","journal-title":"BMC Med Genet"},{"key":"R44-3-20210205","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ymgme.2006.10.007","article-title":"Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people","volume":"90","author":"Sparso","year":"2007","journal-title":"Mol Genet Metab"},{"key":"R45-3-20210205","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1194\/jlr.M700066-JLR200","article-title":"Peroxisome proliferator-activated receptor alpha polymorphisms and postprandial lipemia in healthy men","volume":"48","author":"Tanaka","year":"2007","journal-title":"J Lipid Res"},{"key":"R46-3-20210205","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1097\/01.hjr.0000224484.80349.3f","article-title":"Relationship of classical and nonclassical risk factors with genetic variants relevant to coronary heart disease","volume":"13","author":"Manresa","year":"2006","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R47-3-20210205","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.atherosclerosis.2005.08.034","article-title":"The L162V polymorphism at the peroxisome proliferator-activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT)","volume":"187","author":"Tai","year":"2006","journal-title":"Atherosclerosis"},{"key":"R48-3-20210205","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.2337\/db05-1629","article-title":"Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial","volume":"55","author":"Andrulionyte","year":"2006","journal-title":"Diabetes"},{"key":"R49-3-20210205","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/jn\/135.3.397","article-title":"Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study","volume":"135","author":"Tai","year":"2005","journal-title":"J Nutr"},{"key":"R50-3-20210205","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/ajcn.81.2.523","article-title":"The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men","volume":"81","author":"Paradis","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"R51-3-20210205","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.atherosclerosis.2005.10.002","article-title":"The V227A polymorphism at the PPARA locus is associated with serum lipid concentrations and modulates the association between dietary polyunsaturated fatty acid intake and serum high density lipoprotein concentrations in Chinese women","volume":"187","author":"Chan","year":"2006","journal-title":"Atherosclerosis"},{"key":"R52-3-20210205","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1136\/jmg.39.3.189","article-title":"A Val227Ala polymorphism in the peroxisome proliferator activated receptor alpha (PPAR\u03b1) gene is associated with variations in serum lipid levels","volume":"39","author":"Yamakawa-Kobayashi","year":"2002","journal-title":"J Med Genet"},{"key":"R53-3-20210205","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s100380170080","article-title":"Identification of three missense mutations in the peroxisome proliferator-activated receptor alpha gene in Japanese subjects with maturity-onset diabetes of the young","volume":"46","author":"Hara","year":"2001","journal-title":"J Hum Genet"},{"key":"R54-3-20210205","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1097\/00008571-200412000-00005","article-title":"Response to micronized fenofibrate treatment is associated with the peroxisome proliferator-activated receptors alpha G\/C intron7 polymorphism in subjects with type 2 diabetes","volume":"14","author":"Foucher","year":"2004","journal-title":"Pharmacogenetics"},{"key":"R55-3-20210205","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1478-1336-3-4","article-title":"Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS study","volume":"3","author":"Doney","year":"2005","journal-title":"Nucl Recept"},{"key":"R56-3-20210205","doi-asserted-by":"crossref","first-page":"233","DOI":"10.2143\/AC.62.3.2020810","article-title":"Synergistic effect between polymorphisms of PPARA and ABCA1 genes on the premature coronary artery disease","volume":"62","author":"Balcerzyk","year":"2007","journal-title":"Acta Cardiol"},{"key":"R57-3-20210205","doi-asserted-by":"crossref","first-page":"582","DOI":"10.2337\/diabetes.54.2.582","article-title":"Peroxisome proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes","volume":"54","author":"Flavell","year":"2005","journal-title":"Diabetes"},{"key":"R58-3-20210205","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s00125-007-0668-2","article-title":"Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people","volume":"50","author":"Grarup","year":"2007","journal-title":"Diabetologia"},{"key":"R59-3-20210205","doi-asserted-by":"crossref","first-page":"108","DOI":"10.7150\/ijms.3.108","article-title":"Association of the T+294C polymorphism in PPAR delta with low HDL cholesterol and coronary heart disease risk in women","volume":"3","author":"Aberle","year":"2006","journal-title":"Int J Med Sci"},{"key":"R60-3-20210205","doi-asserted-by":"crossref","first-page":"H2498","DOI":"10.1152\/ajpheart.01092.2006","article-title":"Peroxisome proliferator-activated receptor-delta polymorphisms are associated with physical performance and plasma lipids: the HERITAGE Family Study","volume":"292","author":"Hautala","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"R61-3-20210205","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/sj.ijo.0803450","article-title":"Features of the metabolic syndrome are modulated by an interaction between the peroxisome proliferator-activated receptor-delta -87T>C polymorphism and dietary fat in French-Canadians","volume":"31","author":"Robitaille","year":"2007","journal-title":"Int J Obes (Lond)"},{"key":"R62-3-20210205","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1210\/jc.2006-1785","article-title":"Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention","volume":"92","author":"Stefan","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"R63-3-20210205","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1038\/sj.ijo.0803345","article-title":"Association of peroxisome proliferator-activated receptor delta +294T\/C with body mass index and interaction with peroxisome proliferator-activated receptor alpha L162V","volume":"30","author":"Aberle","year":"2006","journal-title":"Int J Obes (Lond)"},{"key":"R64-3-20210205","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.2337\/diabetes.54.12.3587","article-title":"Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor delta gene is associated with skeletal muscle glucose uptake","volume":"54","author":"Vanttinen","year":"2005","journal-title":"Diabetes"},{"key":"R65-3-20210205","doi-asserted-by":"crossref","first-page":"847","DOI":"10.2337\/diabetes.53.3.847","article-title":"Genetic polymorphisms in peroxisome proliferator-activated receptor delta associated with obesity","volume":"53","author":"Shin","year":"2004","journal-title":"Diabetes"},{"key":"R66-3-20210205","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1111\/j.1464-5491.2006.02001.x","article-title":"Peroxisome proliferator-activated receptor (PPAR) delta genetic polymorphism and its association with insulin resistance index and fasting plasma glucose concentrations in Chinese subjects","volume":"23","author":"Hu","year":"2006","journal-title":"Diabet Med"},{"key":"R67-3-20210205","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.neulet.2006.08.029","article-title":"PPARD haplotype influences cholesterol metabolism but is no risk factor of Alzheimer's disease","volume":"408","author":"Holzapfel","year":"2006","journal-title":"Neurosci Lett"},{"key":"R68-3-20210205","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.2337\/db06-1110","article-title":"Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial","volume":"56","author":"Andrulionyte","year":"2007","journal-title":"Diabetes"},{"key":"R69-3-20210205","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/jn\/136.4.899","article-title":"Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPAR\u03b1, PPAR\u03b3, and adipocyte differentiation in vitro","volume":"136","author":"Shen","year":"2006","journal-title":"J Nutr"}],"container-title":["Current Opinion in Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MOL.0b013e3282f64542","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:57:13Z","timestamp":1786039033000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00041433-200804000-00003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/mol.0b013e3282f64542","relation":{},"ISSN":["0957-9672"],"issn-type":[{"value":"0957-9672","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}