{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T20:51:07Z","timestamp":1648846267404},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1097\/mop.0000000000000202","type":"journal-article","created":{"date-parts":[[2015,2,14]],"date-time":"2015-02-14T15:03:53Z","timestamp":1423926233000},"page":"227-232","source":"Crossref","is-referenced-by-count":1,"title":["Therapies for polycystic kidney disease"],"prefix":"10.1097","volume":"27","author":[{"given":"John J.","family":"Bissler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-14-20210206","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/nrneph.2011.109","article-title":"Why kidneys fail in autosomal dominant polycystic kidney disease.","volume":"7","author":"Grantham","year":"2011","journal-title":"Nature Rev Nephrol"},{"key":"R2-14-20210206","first-page":"159","article-title":"Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis Birth Defects Res C Embryo T","volume":"102","author":"Tran","year":"2014","journal-title":"oday"},{"key":"R3-14-20210206","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2215\/CJN.00060108","article-title":"Approaches to testing new treatments in autosomal dominant polycystic kidney disease: insights from the CRISP and HALT-PKD studies.","volume":"3","author":"Chapman","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"R4-14-20210206","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1681\/ASN.2007060688","article-title":"Vasopressin directly regulates cyst growth in polycystic kidney disease.","volume":"19","author":"Wang","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"R5-14-20210206","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1681\/ASN.2004080660","article-title":"Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease.","volume":"16","author":"Tao","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"R6-14-20210206","doi-asserted-by":"crossref","first-page":"5466","DOI":"10.1073\/pnas.0509694103","article-title":"The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.","volume":"103","author":"Shillingford","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R7-14-20210206","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMoa1003491","article-title":"Everolimus in patients with autosomal dominant polycystic kidney disease.","volume":"363","author":"Walz","year":"2010","journal-title":"N Engl J Med"},{"key":"R8-14-20210206","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1056\/NEJMoa0907419","article-title":"Sirolimus and kidney growth in autosomal dominant polycystic kidney disease.","volume":"363","author":"Serra","year":"2010","journal-title":"N Engl J Med"},{"key":"R9-14-20210206","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s12325-010-0045-2","article-title":"Everolimus in the treatment of renal cell carcinoma and neuroendocrine tumors.","volume":"27","author":"Chan","year":"2010","journal-title":"Adv Ther"},{"key":"R10-14-20210206","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0140-6736(12)61767-X","article-title":"Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial.","volume":"381","author":"Bissler","year":"2013","journal-title":"Lancet"},{"key":"R11-14-20210206","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1056\/NEJMoa063564","article-title":"Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.","volume":"358","author":"Bissler","year":"2008","journal-title":"N Engl J Med"},{"key":"R12-14-20210206","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/(SICI)1520-6408(1999)24:3\/4<309::AID-DVG14>3.0.CO;2-5","article-title":"Developmental expression of urine concentration-associated genes and their altered expression in murine infantile-type polycystic kidney disease.","volume":"24","author":"Gattone","year":"1999","journal-title":"Dev Genet"},{"key":"R13-14-20210206","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1681\/ASN.2006030251","article-title":"Increased water intake decreases progression of polycystic kidney disease in the PCK rat.","volume":"17","author":"Nagao","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"R14-14-20210206","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1056\/NEJMoa1205511","article-title":"Tolvaptan in patients with autosomal dominant polycystic kidney disease.","volume":"367","author":"Torres","year":"2012","journal-title":"N Engl J Med"},{"key":"R15-14-20210206","doi-asserted-by":"crossref","first-page":"R487","DOI":"10.1152\/ajpregu.00177.2014","article-title":"The ins and outs of angiotensin processing within the kidney.","volume":"307","author":"Wilson","year":"2014","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"R16-14-20210206","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00467-013-2480-1","article-title":"Renal tubular dysgenesis.","volume":"29","author":"Gubler","year":"2014","journal-title":"Pediatr Nephrol"},{"key":"R20-14-20210206","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.jpeds.2014.06.015","article-title":"Consensus expert recommendations for the diagnosis and management of autosomal recessive polycystic kidney disease: report of an international conference.","volume":"165","author":"Guay-Woodford","year":"2014","journal-title":"J Pediatr"},{"key":"R21-14-20210206","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/s00467-004-1665-z","article-title":"A mechanistic approach to inherited polycystic kidney disease.","volume":"20","author":"Bissler","year":"2005","journal-title":"Pediatr Nephrol"}],"container-title":["Current Opinion in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MOP.0000000000000202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T03:29:30Z","timestamp":1620962970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00008480-201504000-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1097\/mop.0000000000000202","relation":{},"ISSN":["1040-8703"],"issn-type":[{"value":"1040-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}