{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:06:06Z","timestamp":1786118766259,"version":"build-2736575974"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1097\/mop.0b013e3280e1269a","type":"journal-article","created":{"date-parts":[[2007,5,15]],"date-time":"2007-05-15T04:01:19Z","timestamp":1179201679000},"page":"275-280","source":"Crossref","is-referenced-by-count":10,"title":["Lyme disease update"],"prefix":"10.1097","volume":"19","author":[{"given":"Eric","family":"Hoppa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Bachur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20210206","first-page":"365","article-title":"Lyme disease: United States, 2001-2002.","volume":"53","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R2-8-20210206","first-page":"E0606221","article-title":"Lyme borreliosis: Europe-wide coordinated surveillance and action needed Euro S","volume":"11","author":"Smith","year":"2006","journal-title":"urveill"},{"key":"R3-8-20210206","doi-asserted-by":"crossref","first-page":"604","DOI":"10.3201\/eid1204.051016","article-title":"Epidemic spread of Lyme borreliosis, northeastern United States","volume":"12","author":"Hanincova","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"R4-8-20210206","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1056\/NEJMcp061181","article-title":"Clinical practice. Early Lyme disease","volume":"354","author":"Wormser","year":"2006","journal-title":"N Engl J Med"},{"key":"R5-8-20210206","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1473-3099(03)00722-9","article-title":"Lyme borreliosis","volume":"3","author":"Hengge","year":"2003","journal-title":"Lancet Infect Dis"},{"key":"R6-8-20210206","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1086\/508667","article-title":"The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America","volume":"43","author":"Wormser","year":"2006","journal-title":"Clin Infect Dis"},{"key":"R7-8-20210206","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1056\/NEJM199610243351703","article-title":"Lyme disease in children in southeastern Connecticut. Pediatric Lyme Disease Study Group","volume":"335","author":"Gerber","year":"1996","journal-title":"N Engl J Med"},{"key":"R8-8-20210206","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1542\/peds.96.6.1053","article-title":"Neurologic manifestations in children with Lyme disease","volume":"96","author":"Bingham","year":"1995","journal-title":"Pediatrics"},{"issue":"5","key":"R9-8-20210206","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1542\/peds.103.5.957","article-title":"Characterization of Lyme meningitis and comparison with viral meningitis in children","volume":"103","author":"Eppes","year":"1999","journal-title":"Pediatrics"},{"key":"R10-8-20210206","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s00431-002-1119-1","article-title":"Clinical data and cerebrospinal fluid findings in Lyme meningitis versus aseptic meningitis","volume":"162","author":"Tuerlinckx","year":"2003","journal-title":"Eur J Pediatr"},{"key":"R11-8-20210206","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1097\/01.inf.0000164767.73746.6e","article-title":"Early differentiation of Lyme from enteroviral meningitis","volume":"24","author":"Shah","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"R12-8-20210206","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1542\/peds.2005-0955","article-title":"Prediction of Lyme meningitis in children from a Lyme disease-endemic region: a logistic-regression model using history, physical, and laboratory findings","volume":"117","author":"Avery","year":"2006","journal-title":"Pediatrics"},{"key":"R13-8-20210206","first-page":"531","article-title":"Lyme disease: United States, 1996.","volume":"46","year":"1997","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R14-8-20210206","first-page":"590","article-title":"MMWR Morb Mortal Wkly R","volume":"44","year":"1995","journal-title":"ep"},{"key":"R15-8-20210206","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1128\/CMR.18.3.484-509.2005","article-title":"Diagnosis of Lyme borreliosis","volume":"18","author":"Aguero-Rosenfeld","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"R16-8-20210206","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.7326\/0003-4819-127-12-199712150-00011","article-title":"Laboratory evaluation in the diagnosis of Lyme disease","volume":"127","author":"Tugwell","year":"1997","journal-title":"Ann Intern Med"},{"key":"R17-8-20210206","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0732-8893(03)00080-4","article-title":"Isolation and detection of Borrelia burgdorferi DNA from cerebral spinal fluid, synovial fluid, blood, urine, and ticks using the Roche MagNA Pure system and real-time PCR","volume":"46","author":"Exner","year":"2003","journal-title":"Diagn Microbiol Infect Dis"},{"key":"R18-8-20210206","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1056\/NEJM199401273300401","article-title":"Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis","volume":"330","author":"Nocton","year":"1994","journal-title":"N Engl J Med"},{"key":"R19-8-20210206","doi-asserted-by":"crossref","first-page":"5080","DOI":"10.1128\/JCM.43.10.5080-5084.2005","article-title":"Two-year evaluation of Borrelia burgdorferi culture and supplemental tests for definitive diagnosis of Lyme disease","volume":"43","author":"Coulter","year":"2005","journal-title":"J Clin Microbiol"},{"key":"R20-8-20210206","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/BF02072106","article-title":"Evaluation of the polymerase chain reaction for the detection of Borrelia burgdorferi in cerebrospinal fluid of children with acute peripheral facial palsy","volume":"154","author":"Christen","year":"1995","journal-title":"Eur J Pediatr"},{"key":"R21-8-20210206","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/BF01955900","article-title":"Detection of Borrelia burgdorferi by nested polymerase chain reaction in cerebrospinal fluid and urine of children with neuroborreliosis","volume":"152","author":"Huppertz","year":"1993","journal-title":"Eur J Pediatr"},{"key":"R22-8-20210206","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1128\/JCM.30.7.1646-1653.1992","article-title":"Detection of Borrelia burgdorferi DNA in urine samples and cerebrospinal fluid samples from patients with early and late Lyme neuroborreliosis by polymerase chain reaction","volume":"30","author":"Lebech","year":"1992","journal-title":"J Clin Microbiol"},{"key":"R23-8-20210206","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2165\/00066982-200005020-00007","article-title":"Diagnostic value of PCR for detection of Borrelia burgdorferi DNA in clinical specimens from patients with erythema migrans and Lyme neuroborreliosis","volume":"5","author":"Lebech","year":"2000","journal-title":"Mol Diagn"},{"key":"R24-8-20210206","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1097\/01.inf.0000172903.14077.4c","article-title":"Diagnostic utility of Borrelia burgdorferi cerebrospinal fluid polymerase chain reaction in children with Lyme meningitis","volume":"24","author":"Avery","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"R26-8-20210206","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1097\/01.inf.0000172154.43124.0b","article-title":"New antigens for serologic diagnosis of neuroborreliosis in children","volume":"24","author":"Heikkila","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"R27-8-20210206","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/01.inf.0000145411.57449.f3","article-title":"Inaccurate information about Lyme disease on the internet","volume":"23","author":"Cooper","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"R28-8-20210206","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1089\/153036602321653842","article-title":"Controlled trials of antibiotic treatment in patients with posttreatment chronic Lyme disease","volume":"2","author":"Klempner","year":"2002","journal-title":"Vector Borne Zoonotic Dis"},{"key":"R29-8-20210206","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1056\/NEJM200107123450202","article-title":"Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease","volume":"345","author":"Klempner","year":"2001","journal-title":"N Engl J Med"},{"key":"R30-8-20210206","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1086\/432733","article-title":"A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease","volume":"192","author":"Klempner","year":"2005","journal-title":"J Infect Dis"},{"key":"R31-8-20210206","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/00002281-200207000-00008","article-title":"Lyme arthritis and post-Lyme disease syndrome","volume":"14","author":"Weinstein","year":"2002","journal-title":"Curr Opin Rheumatol"},{"key":"R32-8-20210206","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1212\/01.WNL.0000068030.26992.25","article-title":"Cognitive function in posttreatment Lyme disease: do additional antibiotics help?","volume":"60","author":"Kaplan","year":"2003","journal-title":"Neurology"},{"key":"R33-8-20210206","first-page":"125","article-title":"Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease.","volume":"54","year":"2005","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R34-8-20210206","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1086\/320721","article-title":"Borrelia lonestari infection after a bite by an Amblyomma americanum tick","volume":"183","author":"James","year":"2001","journal-title":"J Infect Dis"},{"key":"R35-8-20210206","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1128\/CVI.00238-06","article-title":"Serologic evaluation of patients from Missouri with erythema migrans-like skin lesions with the C6 Lyme test","volume":"13","author":"Philipp","year":"2006","journal-title":"Clin Vaccine Immunol"},{"key":"R36-8-20210206","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1086\/427289","article-title":"Microbiologic evaluation of patients from Missouri with erythema migrans","volume":"40","author":"Wormser","year":"2005","journal-title":"Clin Infect Dis"},{"key":"R37-8-20210206","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1089\/vbz.2005.5.383","article-title":"Distribution of Borreliae among ticks collected from eastern states","volume":"5","author":"Taft","year":"2005","journal-title":"Vector Borne Zoonotic Dis"},{"key":"R38-8-20210206","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1086\/432935","article-title":"Prospective clinical evaluation of patients from Missouri and New York with erythema migrans-like skin lesions","volume":"41","author":"Wormser","year":"2005","journal-title":"Clin Infect Dis"},{"key":"R39-8-20210206","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1128\/CMR.00011-06","article-title":"Coinfections acquired from ixodes ticks","volume":"19","author":"Swanson","year":"2006","journal-title":"Clin Microbiol Rev"},{"key":"R40-8-20210206","doi-asserted-by":"crossref","first-page":"4172","DOI":"10.1128\/JCM.39.11.4172-4174.2001","article-title":"High prevalence of granulocytic Ehrlichiae and Borrelia burgdorferi sensu lato in Ixodes ricinus ticks from Bulgaria","volume":"39","author":"Christova","year":"2001","journal-title":"J Clin Microbiol"},{"key":"R41-8-20210206","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0025-7125(03)00092-0","article-title":"Babesiosis","volume":"86","author":"Krause","year":"2002","journal-title":"Med Clin North Am"},{"key":"R42-8-20210206","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1001\/jama.1996.03530450047031","article-title":"Concurrent Lyme disease and babesiosis. Evidence for increased severity and duration of illness","volume":"275","author":"Krause","year":"1996","journal-title":"JAMA"},{"key":"R43-8-20210206","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/ajcp\/107.2.142","article-title":"Positive Lyme disease serology in patients with clinical and laboratory evidence of human granulocytic ehrlichiosis","volume":"107","author":"Wormser","year":"1997","journal-title":"Am J Clin Pathol"},{"key":"R44-8-20210206","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1097\/01.pec.0000190229.35481.d2","article-title":"Junctional rhythm in association with neuroborreliosis","volume":"21","author":"Kaltman","year":"2005","journal-title":"Pediatr Emerg Care"},{"key":"R45-8-20210206","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.jpeds.2005.11.031","article-title":"Transient prolonged corrected QT interval in Lyme disease","volume":"148","author":"Seslar","year":"2006","journal-title":"J Pediatr"},{"key":"R46-8-20210206","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0025-7125(03)00087-7","article-title":"Cardiac manifestations of Lyme disease","volume":"86","author":"Pinto","year":"2002","journal-title":"Med Clin North Am"}],"container-title":["Current Opinion in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MOP.0b013e3280e1269a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:39:37Z","timestamp":1786034377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00008480-200706000-00008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/mop.0b013e3280e1269a","relation":{},"ISSN":["1040-8703"],"issn-type":[{"value":"1040-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}