{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:03:10Z","timestamp":1786118590934,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1097\/mop.0b013e3283425457","type":"journal-article","created":{"date-parts":[[2010,12,28]],"date-time":"2010-12-28T23:25:16Z","timestamp":1293578716000},"page":"121-125","source":"Crossref","is-referenced-by-count":7,"title":["Changing the topography of acne with topical medications"],"prefix":"10.1097","volume":"23","author":[{"given":"Joyce I","family":"Imahiyerobo-Ip","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G","family":"Dinulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-21-20210206","first-page":"577","article-title":"Prevalence of facial acne in adults","volume":"41","author":"Goulden","year":"1999","journal-title":"J Am Acad Dermatol"},{"key":"R2-21-20210206","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1136\/bmj.38987.606701.80","article-title":"Acne","volume":"333","author":"Purdy","year":"2006","journal-title":"BMJ"},{"issue":"5","key":"R3-21-20210206","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/0190-9622(95)90416-6","article-title":"New understanding of the pathogenesis of acne","volume":"32","author":"Leyden","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"R4-21-20210206","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1001\/jama.292.6.726","article-title":"Treatment of acne vulgaris","volume":"292","author":"Haider","year":"2004","journal-title":"JAMA"},{"key":"R5-21-20210206","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1001\/archfami.9.2.179","article-title":"New treatments and therapeutic strategies for acne","volume":"9","author":"Thiboutot","year":"2000","journal-title":"Arch Family Med"},{"key":"R6-21-20210206","doi-asserted-by":"crossref","first-page":"ITC1","DOI":"10.7326\/0003-4819-149-1-200807010-01001","article-title":"In the clinic. Acne","volume":"149","author":"Bershad","year":"2008","journal-title":"Ann Intern Med"},{"key":"R7-21-20210206","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1542\/peds.2005-2022","article-title":"Expert committee recommendations for acne management","volume":"118","author":"Zaenglein","year":"2006","journal-title":"Pediatrics"},{"issue":"Suppl 52","key":"R8-21-20210206","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1046\/j.1365-2133.1998.1390s2008.x","article-title":"Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation","volume":"138","author":"Martin","year":"1998","journal-title":"Br J Dermatol"},{"issue":"Suppl 1","key":"R9-21-20210206","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1067\/mjd.2003.618","article-title":"Management of acne: a report from the Global Alliance to Improve Outcomes in Acne","volume":"49","author":"Gollnick","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"R10-21-20210206","first-page":"525","article-title":"Topical antibacterial agents","author":"Yang","year":"2007"},{"issue":"Suppl 5","key":"R11-21-20210206","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaad.2009.01.019","article-title":"New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group","volume":"60","author":"Thiboutot","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"R12-21-20210206","first-page":"482","article-title":"Benzoyl peroxide development, pharmacology, formulation and clinical uses in topical fixed-combinations","volume":"9","author":"Harper","year":"2010","journal-title":"J Drugs Dermatol"},{"key":"R13-21-20210206","first-page":"405","article-title":"Clindamycin phosphate 1.2%-tretinoin 0.025% gel: vehicle characteristics, stability, and tolerability","volume":"81","author":"Del Rosso","year":"2008","journal-title":"Cutis"},{"key":"R14-21-20210206","first-page":"607","article-title":"Clinical safety and efficacy studies of a novel formulation combining 1.2% clindamycin phosphate and 0.025% tretinoin for the treatment of acne vulgaris","volume":"6","author":"Schlessinger","year":"2007","journal-title":"J Drugs Dermatol"},{"key":"R15-21-20210206","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1525-1470.2008.00862.x","article-title":"A novel gel formulation of 0.25% tretinoin and 1.2% clindamycin phosphate: efficacy in acne vulgaris patients aged 12\u201318 years","volume":"26","author":"Eichenfield","year":"2009","journal-title":"Pediatr Dermatol"},{"key":"R16-21-20210206","first-page":"358","article-title":"Safety of a novel gel formulation of clindamycin phosphate 1.2%\u2013tretinoin 0.025%: results from a 52-week open-label study","volume":"82","author":"Kircik","year":"2008","journal-title":"Cutis"},{"key":"R17-21-20210206","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.jaad.2007.06.006","article-title":"Adapalene\u2013benzoyl peroxide, a fixed-dose combination for treatment of acne vulgaris: results of a multicenter, randomized double-blind, controlled study","volume":"57","author":"Thiboutot","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"R18-21-20210206","first-page":"110","article-title":"A North American study of adapalene\u2013benzoyl peroxide combination gel in the treatment of acne","volume":"84","author":"Gold","year":"2009","journal-title":"Cutis"},{"key":"R19-21-20210206","first-page":"524","article-title":"Adapalene 0.1% and benzoyl peroxide 2.5% as a fixed-dose combination gel is as well tolerated as the individual components alone in terms of cumulative irritancy","volume":"18","author":"Loesche","year":"2008","journal-title":"Eur J Dermatol"},{"key":"R20-21-20210206","first-page":"899","article-title":"Long-term safety and efficacy of a unique fixed-dose combination gel of adapalene 0.1% and benzoyl peroxide 2.5% for the treatment of acne vulgaris","volume":"6","author":"Pariser","year":"2007","journal-title":"J Drugs Dermatol"},{"key":"R21-21-20210206","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2165\/00128071-200910040-00002","article-title":"Dapsone 5% gel: a review of its efficacy and safety in the treatment of acne vulgaris","volume":"10","author":"Stotland","year":"2009","journal-title":"Am J Clin Dermatol"},{"key":"R22-21-20210206","doi-asserted-by":"crossref","first-page":"439e1","DOI":"10.1016\/j.jaad.2006.10.005","article-title":"Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris","volume":"56","author":"Draelos","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"R23-21-20210206","first-page":"981","article-title":"Dapsone gel 5% for the treatment of acne vulgaris: safety and efficacy of long-term (1 year) treatment","volume":"6","author":"Lucky","year":"2007","journal-title":"J Drugs Dermatol"},{"key":"R24-21-20210206","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1001\/archdermatol.2008.518","article-title":"Hematologic safety of dapsone gel, 5%, for topical treatment of acne vulgaris","volume":"144","author":"Piette","year":"2008","journal-title":"Arch Dermatol"},{"key":"R25-21-20210206","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jaad.2009.09.056","article-title":"Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice: Part I. Acne vulgaris: when and why consider photodynamic therapy","volume":"63","author":"Sakamoto","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"R26-21-20210206","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1128\/JB.133.2.811-815.1978","article-title":"Comparative studies of porphyrin production in Propionibacterium acnes and Propionibacterium granulosum","volume":"133","author":"Lee","year":"1978","journal-title":"J Bacteriol"},{"key":"R27-21-20210206","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/14764170310001276","article-title":"The effective treatment of acne vulgaris by a high-intensity, narrow band 405\u2013420 nm light source","volume":"5","author":"Elman","year":"2003","journal-title":"J Cosmetic Laser Therapy"},{"key":"R28-21-20210206","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.1523-1747.2000.00046.x","article-title":"Topical ALA-photodynamic therapy for the treatment of acne vulgaris","volume":"115","author":"Hongcharu","year":"2000","journal-title":"J Invest Dermatol"}],"container-title":["Current Opinion in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MOP.0b013e3283425457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:27:02Z","timestamp":1786033622000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00008480-201102000-00021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/mop.0b013e3283425457","relation":{},"ISSN":["1040-8703"],"issn-type":[{"value":"1040-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}