{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:25:28Z","timestamp":1789734328775,"version":"4.0.1"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1097\/mot.0b013e32832e7158","type":"journal-article","created":{"date-parts":[[2009,9,16]],"date-time":"2009-09-16T07:18:20Z","timestamp":1253085500000},"page":"571-576","source":"Crossref","is-referenced-by-count":25,"title":["Innate immunity in heart transplantation"],"prefix":"10.1097","volume":"14","author":[{"given":"Timothy M","family":"Millington","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joren C","family":"Madsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-22-20210206","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1161\/CIRCULATIONAHA.107.711911","article-title":"Cardiac allograft vasculopathy: recent developments","volume":"117","author":"Schmauss","year":"2008","journal-title":"Circulation"},{"key":"R2-22-20210206","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/00000478-199404000-00002","article-title":"Peritransplant injury to the myocardium associated with the development of accelerated arteriosclerosis in heart transplant recipients","volume":"18","author":"Gaudin","year":"1994","journal-title":"Am J Surg Pathol"},{"key":"R3-22-20210206","doi-asserted-by":"crossref","first-page":"H1","DOI":"10.1152\/ajpheart.00995.2008","article-title":"Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart","volume":"296","author":"Chao","year":"2009","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"R4-22-20210206","doi-asserted-by":"crossref","first-page":"S157","DOI":"10.1016\/j.healun.2005.11.341","article-title":"329: TLR2 signaling blocks regulatory T cell suppression leading to immune activation following cardiac allotransplantation","volume":"25","author":"Ramachandran","year":"2006","journal-title":"J Heart Lung Transplant"},{"key":"R5-22-20210206","doi-asserted-by":"crossref","first-page":"12542","DOI":"10.1074\/jbc.M310175200","article-title":"mRNA is an endogenous ligand for Toll-like receptor 3","volume":"279","author":"Karik\u00f3","year":"2004","journal-title":"J Biol Chem"},{"key":"R6-22-20210206","doi-asserted-by":"crossref","first-page":"H251","DOI":"10.1152\/ajpheart.00398.2006","article-title":"Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury","volume":"292","author":"Hardarson","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"R7-22-20210206","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.4049\/jimmunol.181.3.1692","article-title":"Mechanisms underlying blockade of allograft acceptance by TLR ligands","volume":"181","author":"Porrett","year":"2008","journal-title":"J Immunol"},{"key":"R8-22-20210206","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/MOT.0b013e3282f3df04","article-title":"Activation of the innate immune system by the endogenous ligand hyaluronan","volume":"13","author":"Shirali","year":"2008","journal-title":"Curr Opin Organ Transplant"},{"key":"R9-22-20210206","doi-asserted-by":"crossref","first-page":"H2805","DOI":"10.1152\/ajpheart.00299.2008","article-title":"Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion","volume":"294","author":"Zou","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"R10-22-20210206","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.1161\/CIRCULATIONAHA.108.769331","article-title":"High-mobility group box-1 in ischemia-reperfusion injury of the heart","volume":"117","author":"Andrassy","year":"2008","journal-title":"Circulation"},{"key":"R11-22-20210206","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1016\/j.athoracsur.2008.01.043","article-title":"Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia","volume":"85","author":"Cha","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"R12-22-20210206","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s10753-008-9079-x","article-title":"Sequential expression of TLR4 and its effects on the myocardium of rats with myocardial ischemia-reperfusion injury","volume":"31","author":"Yang","year":"2008","journal-title":"Inflammation"},{"key":"R13-22-20210206","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1097\/01.tp.0000287597.87571.17","article-title":"Toll-like receptor 4 mediates the early inflammatory response after cold ischemia\/reperfusion","volume":"84","author":"Kaczorowski","year":"2007","journal-title":"Transplantation"},{"key":"R14-22-20210206","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1097\/01.TP.0000137930.40597.03","article-title":"Evidence for a role of toll-like receptor 4 in development of chronic allograft rejection after cardiac transplantation","volume":"78","author":"Methe","year":"2004","journal-title":"Transplantation"},{"key":"R15-22-20210206","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1111\/j.1600-6143.2006.01489.x","article-title":"TLR engagement prevents transplantation tolerance","volume":"6","author":"Chen","year":"2006","journal-title":"Am J Transplant"},{"key":"R16-22-20210206","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nature07665","article-title":"Adaptive immune features of natural killer cells","volume":"457","author":"Sun","year":"2009","journal-title":"Nature"},{"key":"R17-22-20210206","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1073\/pnas.0813192106","article-title":"Cytokine-induced memory-like natural killer cells","volume":"106","author":"Cooper","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R18-22-20210206","doi-asserted-by":"crossref","first-page":"7818","DOI":"10.4049\/jimmunol.180.12.7818","article-title":"The Innate NK Cells, Allograft Rejection, and a Key Role for IL-15","volume":"180","author":"Kroemer","year":"2008","journal-title":"J Immunol"},{"key":"R19-22-20210206","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1034\/j.1600-6143.2001.010108.x","article-title":"Different mechanisms of cardiac allograft rejection in wildtype and CD28-deficient mice","volume":"1","author":"Szot","year":"2001","journal-title":"Am J Transplant"},{"key":"R20-22-20210206","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1600-6143.2005.01226.x","article-title":"Role of natural killer cell subsets in cardiac allograft rejection","volume":"6","author":"McNerney","year":"2006","journal-title":"Am J Transplant"},{"key":"R21-22-20210206","doi-asserted-by":"crossref","first-page":"6416","DOI":"10.4049\/jimmunol.179.10.6416","article-title":"The activating immunoreceptor NKG2D and its ligands are involved in allograft transplant rejection","volume":"179","author":"Kim","year":"2007","journal-title":"J Immunol"},{"key":"R22-22-20210206","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1399-3089.2006.00327.x","article-title":"NK-cell-dependent acute xenograft rejection in the mouse heart-to-rat model","volume":"13","author":"Chen","year":"2006","journal-title":"Xenotransplantation"},{"key":"R23-22-20210206","doi-asserted-by":"crossref","first-page":"S212","DOI":"10.1016\/j.healun.2007.11.434","article-title":"422: natural killer cells deplete from peripheral blood and increase in myocardial tissue during acute rejection following heart transplantation","volume":"27","author":"Fildes","year":"2008","journal-title":"J Heart Lung Transplant"},{"key":"R24-22-20210206","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.healun.2007.11.571","article-title":"Natural killer cells in peripheral blood and lung tissue are associated with chronic rejection after lung transplantation","volume":"27","author":"Fildes","year":"2008","journal-title":"J Heart Lung Transplant"},{"key":"R25-22-20210206","doi-asserted-by":"crossref","first-page":"3424","DOI":"10.4049\/jimmunol.175.5.3424","article-title":"NK cells can trigger allograft vasculopathy: the role of hybrid resistance in solid organ allografts","volume":"175","author":"Uehara","year":"2005","journal-title":"J Immunol"},{"key":"R26-22-20210206","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.4049\/jimmunol.172.4.2001","article-title":"Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor","volume":"172","author":"Hamerman","year":"2004","journal-title":"J Immunol"},{"key":"R27-22-20210206","doi-asserted-by":"crossref","first-page":"6711","DOI":"10.4049\/jimmunol.181.10.6711","article-title":"Interaction of monocytes with NK cells upon Toll-like receptor-induced expression of the NKG2D ligand MICA","volume":"181","author":"Kloss","year":"2008","journal-title":"J Immunol"},{"key":"R28-22-20210206","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1002\/eji.200838659","article-title":"A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells","volume":"38","author":"Hochweller","year":"2008","journal-title":"Eur J Immunol"},{"key":"R29-22-20210206","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1097\/00007890-199909270-00024","article-title":"Complement deposition in early cardiac transplant biopsies is associated with ischemic injury and subsequent rejection episodes","volume":"68","author":"Baldwin","year":"1999","journal-title":"Transplantation"},{"key":"R30-22-20210206","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1432-2277.2004.00037.x","article-title":"Capillary deposition of the complement fragment C4d in cardiac allograft biopsies is associated with allograft vasculopathy","volume":"18","author":"Poelzl","year":"2005","journal-title":"Transpl Int"},{"key":"R31-22-20210206","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1097\/TP.0b013e3181889831","article-title":"Complement gene expression in human cardiac allograft biopsies as a correlate of histologic grade of injury","volume":"86","author":"Keslar","year":"2008","journal-title":"Transplantation"},{"key":"R32-22-20210206","doi-asserted-by":"crossref","first-page":"4580","DOI":"10.4049\/jimmunol.181.7.4580","article-title":"Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection","volume":"181","author":"Pavlov","year":"2008","journal-title":"J Immunol"},{"key":"R33-22-20210206","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1097\/TP.0b013e31818a68e2","article-title":"Posttransplant ischemia-reperfusion injury in transplanted heart is prevented by a minibody to the fifth component of complement","volume":"86","author":"Ferraresso","year":"2008","journal-title":"Transplantation"},{"key":"R34-22-20210206","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.healun.2008.08.011","article-title":"Mannose-binding lectin deficiency offers protection from acute graft rejection after heart transplantation","volume":"27","author":"Fildes","year":"2008","journal-title":"J Heart Lung Transplant"}],"container-title":["Current Opinion in Organ Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MOT.0b013e32832e7158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T03:52:30Z","timestamp":1620964350000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00075200-200910000-00022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/mot.0b013e32832e7158","relation":{},"ISSN":["1087-2418"],"issn-type":[{"value":"1087-2418","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}