{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T20:12:33Z","timestamp":1793045553735,"version":"4.5.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1097\/mpa.0b013e3181d3cdf0","type":"journal-article","created":{"date-parts":[[2010,6,8]],"date-time":"2010-06-08T05:25:25Z","timestamp":1275974725000},"page":"1047-1056","source":"Crossref","is-referenced-by-count":14,"title":["Characterization of Polyamine Homeostasis in l-Ornithine-Induced Acute Pancreatitis in Rats"],"prefix":"10.1097","volume":"39","author":[{"given":"Gy\u00f6rgy","family":"Bicz\u00f3","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Hegyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta","family":"Sinervirta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e1ndor","family":"Berczi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e1ndor","family":"D\u00f3sa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Siska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9la","family":"Iv\u00e1nyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikt\u00f3ria","family":"Venglovecz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Tak\u00e1cs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena","family":"Alhonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Rakonczay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-17-20210212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj20031327","article-title":"A perspective of polyamine metabolism.","volume":"376","author":"Wallace","year":"2003","journal-title":"Biochem J"},{"key":"R2-17-20210212","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.clnu.2004.11.001","article-title":"Polyamines: metabolism and implications in human diseases.","volume":"24","author":"Moinard","year":"2005","journal-title":"Clin Nutr"},{"key":"R3-17-20210212","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000199867","article-title":"Role of ornithine decarboxylase and polyamines in camostate (Foy-305)-induced pancreatic growth in rats.","volume":"43","author":"Loser","year":"1989","journal-title":"Digestion"},{"key":"R4-17-20210212","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1111\/j.1432-1033.2004.04009.x","article-title":"Genetic approaches to the cellular functions of polyamines in mammals.","volume":"271","author":"Janne","year":"2004","journal-title":"Eur J Biochem"},{"key":"R5-17-20210212","doi-asserted-by":"crossref","first-page":"8290","DOI":"10.1073\/pnas.140122097","article-title":"Activation of polyamine catabolism in transgenic rats induces acute pancreatitis.","volume":"97","author":"Alhonen","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R6-17-20210212","doi-asserted-by":"crossref","first-page":"115","DOI":"10.2353\/ajpath.2006.050518","article-title":"Activated polyamine catabolism in acute pancreatitis: alpha-methylated polyamine analogues prevent trypsinogen activation and pancreatitis-associated mortality.","volume":"168","author":"Hyvonen","year":"2006","journal-title":"Am J Pathol"},{"key":"R7-17-20210212","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1042\/BST0350326","article-title":"Mechanisms of polyamine catabolism-induced acute pancreatitis.","volume":"35","author":"Hyvonen","year":"2007","journal-title":"Biochem Soc Trans"},{"key":"R8-17-20210212","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000114851","article-title":"Polyamine levels in the pancreas and the blood change according to the severity of pancreatitis.","volume":"8","author":"Jin","year":"2008","journal-title":"Pancreatology"},{"key":"R9-17-20210212","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1097\/CCM.0b013e31817d7f5c","article-title":"A new severe acute necrotizing pancreatitis model induced by L-ornithine in rats.","volume":"36","author":"Rakonczay","year":"2008","journal-title":"Crit Care Med"},{"key":"R10-17-20210212","first-page":"441","article-title":"A new synthesis of alpha-methylspermidine.","volume":"30","author":"Grigorenko","year":"2004","journal-title":"Bioorgan Khim (Moscow)"},{"key":"R11-17-20210212","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0378-4347(92)80093-6","article-title":"Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by high-performance liquid chromatography.","volume":"574","author":"Hyvonen","year":"1992","journal-title":"J Chromatogr"},{"key":"R12-17-20210212","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/S0021-9258(18)62370-1","article-title":"On the purification of L-ornithine decarboxylase from rat prostate and effects of thiol compounds on the enzyme.","volume":"246","author":"Janne","year":"1971","journal-title":"J Biol Chem"},{"key":"R13-17-20210212","first-page":"2424","article-title":"N,N-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts.","volume":"52","author":"Bernacki","year":"1992","journal-title":"Cancer Res"},{"key":"R14-17-20210212","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1159\/000179155","article-title":"Measurement of neutrophil content in brain and lung tissue by a modified myeloperoxidase assay.","volume":"16","author":"Kuebler","year":"1996","journal-title":"Int J Microcirc Clin Exp"},{"key":"R15-17-20210212","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0891-5849(02)01373-4","article-title":"NF-kappaB activation is detrimental in arginineinduced acute pancreatitis.","volume":"34","author":"Rakonczay","year":"2003","journal-title":"Free Radic Biol Med"},{"key":"R16-17-20210212","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"R17-17-20210212","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4.","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"R18-17-20210212","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1379\/1466-1268(1999)004<0139:ULOHEW>2.3.CO;2","article-title":"Ultrastructural localization of HSP-72 examined with a new polyclonal antibody raised against the truncated variable domain of the heat shock protein.","volume":"4","author":"Kurucz","year":"1999","journal-title":"Cell Stress Chaperones"},{"key":"R19-17-20210212","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/jcp.10268","article-title":"Heat shock proteins and the pancreas.","volume":"195","author":"Rakonczay","year":"2003","journal-title":"J Cell Physiol"},{"key":"R20-17-20210212","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1136\/gut.2007.124115","article-title":"The role of NF-B activation in the pathogenesis of acute pancreatitis.","volume":"57","author":"Rakonczay","year":"2008","journal-title":"Gut"},{"key":"R21-17-20210212","doi-asserted-by":"crossref","first-page":"4953","DOI":"10.1128\/MCB.02034-06","article-title":"Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.","volume":"27","author":"Pirinen","year":"2007","journal-title":"Mol Cell Biol"},{"key":"R22-17-20210212","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.surg.2008.03.029","article-title":"A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate.","volume":"144","author":"Jin","year":"2008","journal-title":"Surgery"},{"key":"R23-17-20210212","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1021\/jm00082a013","article-title":"alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.","volume":"35","author":"Lakanen","year":"1992","journal-title":"J Med Chem"},{"key":"R24-17-20210212","doi-asserted-by":"crossref","first-page":"6595","DOI":"10.1074\/jbc.M412788200","article-title":"Metabolic stability of alpha-methylated polyamine derivatives and their use as substitutes for the natural polyamines.","volume":"280","author":"Jarvinen","year":"2005","journal-title":"J Biol Chem"},{"key":"R25-17-20210212","doi-asserted-by":"crossref","first-page":"39867","DOI":"10.1074\/jbc.M205967200","article-title":"A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.","volume":"277","author":"Rasanen","year":"2002","journal-title":"J Biol Chem"}],"container-title":["Pancreas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00006676-201010000-00017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:23:00Z","timestamp":1786040580000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006676-201010000-00017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/mpa.0b013e3181d3cdf0","relation":{},"ISSN":["0885-3177"],"issn-type":[{"value":"0885-3177","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]}}}