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In a randomized controlled trial, VLBW infants (n = 81) received either repeated daily small volume enemas if complete spontaneous meconium passage failed within 24 h or no intervention. Small volume enemas did not accelerate complete meconium evacuation, which occurred after 6.0 to 9.6 (95% CI) d in the intervention group and after 7.7 to 11.0 (95% CI) d in the control group. No adverse events were observed. Daily administration of small volume enemas had no effect on total meconium evacuation defined by the time of last meconium passage.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e31802c685a","type":"journal-article","created":{"date-parts":[[2007,1,24]],"date-time":"2007-01-24T09:02:56Z","timestamp":1169629376000},"page":"270-273","source":"Crossref","is-referenced-by-count":34,"title":["Small Volume Enemas Do Not Accelerate Meconium Evacuation in Very Low Birth Weight Infants"],"prefix":"10.1002","volume":"44","author":[{"given":"Nadja","family":"Haiden","sequence":"first","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Jilma","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Gerhold","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Klebermass","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea R","family":"Prusa","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Kuhle","sequence":"additional","affiliation":[{"name":"Stollery Children's Hospital Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaudia","family":"Rohrmeister","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Kohlhauser\u2010Vollmuth","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold","family":"Pollak","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics Medical University of Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-5108(05)70015-4"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607193017006537"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(55)80205-3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(57)80120-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01954520"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2001.tb00441.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.285"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.6.1199"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)92296-6"},{"key":"e_1_2_6_11_1","first-page":"846","article-title":"Comparative efficacy of glycerin enemas and suppository chips in neonates","volume":"12","author":"Zenk KE","year":"1993","journal-title":"Clin Pharm"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MPG.0b013e31802c685a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T13:58:57Z","timestamp":1705586337000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MPG.0b013e31802c685a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["10.1097\/MPG.0b013e31802c685a"],"URL":"https:\/\/doi.org\/10.1097\/mpg.0b013e31802c685a","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2]]}}}