{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:47:02Z","timestamp":1789915622228,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>To evaluate the implementation of the World Health Organization guidelines for the treatment of children with severe acute malnutrition in a class I hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Paitents and Methods:<\/jats:title><jats:p>Descriptive and prospective study of 335 children under the age of 6, admitted between 2001 and 2005 for severe acute malnutrition (83%) and moderate acute malnutrition associated with illness (17%). The care of the children was provided by clinicians and medical staff trained under World Health Organization guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Kwashiorkor was a common result in children with severe acute malnutrition (60.8%); 58% were younger than 1 year old. Complications upon admission were diarrhea (68.4%) and anemia (51.1%), and the most common complication during hospital stay was sepsis (9%). Overall, 61.7% attained \u22121 standard deviation of weight for height after an average stay of 3 weeks in the hospital; 5.1% were sent to tertiary care hospitals. Overall, mortality during the 5 years was 5.7%, with sepsis the most common cause. In the first year, the mortality rate was 8.7%; it decreased to 4.0% in the last year. The mortality rate was significantly higher in children with edema. Children with moderate acute malnutrition had similar complications and mortality when compared with children with severe acute malnutrition (5.3%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Once the World Health Organization guidelines were implemented, low mortality rates were achieved in children with severe acute malnutrition in class I hospitals.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e318156c2c3","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T14:45:23Z","timestamp":1236264323000},"page":"322-328","source":"Crossref","is-referenced-by-count":28,"title":["Treatment of Severe Malnutrition in Children: Experience in Implementing the World Health Organization Guidelines in Turbo, Colombia"],"prefix":"10.1002","volume":"46","author":[{"given":"Carlos","family":"Bernal","sequence":"first","affiliation":[{"name":"Schools of Medicine Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Vel\u00e1squez","sequence":"additional","affiliation":[{"name":"Nutrition and Dietetics Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Alcaraz","sequence":"additional","affiliation":[{"name":"Nursing University of Antioquia Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Botero","sequence":"additional","affiliation":[{"name":"Schools of Medicine Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,3]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Management of Severe Malnutrition: A Manual for Physicians and Other Senior Health Workers","author":"World Health Organization.","year":"1999"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000006478"},{"key":"e_1_2_8_4_1","volume-title":"Estado Mundial de la Infancia","author":"Fondo de las Naciones Unidas Para la Infancia.","year":"1998"},{"key":"e_1_2_8_5_1","volume-title":"40aSesi\u00f3n del Subcomit\u00e9 de Planificaci\u00f3n y Programaci\u00f3n del Comit\u00e9 Ejecutivo OPS\u2010OMS","author":"Organizaci\u00f3n Mundial de la Salud.","year":"2006"},{"key":"e_1_2_8_6_1","first-page":"223","article-title":"Why have mortality rates for severe malnutrition remained so high","volume":"74","author":"Schofield C","year":"1996","journal-title":"Bull WHO"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7381.146"},{"key":"e_1_2_8_8_1","first-page":"89","volume-title":"Gu\u00eda B\u00e1sica Para el Nivel de Referencia Hospitalaria","author":"Organizaci\u00f3n Mundial de la Salud.","year":"2001"},{"key":"e_1_2_8_9_1","first-page":"87","article-title":"Diagn\u00f3stico de salud en Antioquia","volume":"25","author":"Direcci\u00f3n Seccional de Salud de Antioquia.","year":"2000","journal-title":"Rev Epidemiol Antioq"},{"key":"e_1_2_8_10_1","first-page":"12","article-title":"Aplicaci\u00f3n de la gu\u00eda de la Organizaci\u00f3n Mundial de la Salud para el tratamiento de los ni\u00f1os con desnutrici\u00f3n grave","volume":"22","author":"Bernal C","year":"2004","journal-title":"Invest Educ Enferm"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/32.3.607"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)07499-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15894-7"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92885-1"},{"key":"e_1_2_8_15_1","first-page":"237","article-title":"Implementation of WHO guidelines on management of severe malnutrition in hospitals in Africa","volume":"81","author":"Deen JL","year":"2003","journal-title":"Bull WHO"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2001.tb07364.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0022-3476(03)00500-6"},{"key":"e_1_2_8_18_1","unstructured":"World Heath Organization.Reduced Osmolarity Oral Rehydration Salts (ORS) Formulation. Report from a meeting of experts jointly organized by UNICEF and WHO.http:\/\/www.who.int\/child\u2010adolescent\u2010health\/New_Publications\/NEWS\/Expert_consultation.htm. Accessed November 12 2006."},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a011699"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2000.107512"},{"key":"e_1_2_8_21_1","first-page":"29","article-title":"Cambios en la concentraci\u00f3n s\u00e9rica de hierro \u2018libre\u2019 en ni\u00f1os con desnutrici\u00f3n aguda grave bajo tratamiento de recuperaci\u00f3n nutricional. 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