{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:48:37Z","timestamp":1761630517888},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>The aim of this study was to determine the epidemiological and clinical characteristics of inflammatory bowel disease (IBD) in children in central and western Slovenia during a 12\u2010year period (1994\u20132005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>The medical records of patients with newly diagnosed IBD during the period of 1994\u20132005 were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>In the 12\u2010year study period, 137 children received new diagnoses of IBD, 60% had Crohn disease (CD), 28% had ulcerative colitis (UC), and 12% had indeterminate colitis (IC). The mean annual incidence of IBD for the whole 12\u2010year period was 4.03\/100,000 children; for CD 2.42, for UC 1.14, and for IC 0.47. The annual incidence of IBD rose from 3.04 in the period 1994\u20131999 to 5.14 in the period 2000\u20132005. The incidences of CD, UC, and IC rose from 1.99, 0.77, and 0.28, respectively, in the first 6 years to 2.88, 1.57, and 0.69, respectively, in the second 6\u2010year period. The most common type of CD at presentation was inflammatory. Pancolitis was the most frequent form of UC. Almost half of the patients had a severe form of CD at its onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>The incidence of total pediatric IBD in central and western Slovenia is high and seems to be still rising. CD is the most prevalent form of IBD; its incidence is comparable with that reported in other central and western European countries. The incidences of UC and IC are rising more rapidly than the incidence of CD.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e318164d903","type":"journal-article","created":{"date-parts":[[2009,5,21]],"date-time":"2009-05-21T13:37:54Z","timestamp":1242913074000},"page":"579-586","source":"Crossref","is-referenced-by-count":39,"title":["Epidemiology of Pediatric Chronic Inflammatory Bowel Disease in Central and Western Slovenia, 1994\u20132005"],"prefix":"10.1002","volume":"48","author":[{"given":"Rok","family":"Orel","sequence":"first","affiliation":[{"name":"University Children's Hospital Department of Gastroenterology Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Kamhi","sequence":"additional","affiliation":[{"name":"University Children's Hospital Department of Gastroenterology Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaj","family":"Vidmar","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Informatics Faculty of Medicine University of Ljubljana Ljubljana Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Mamula","sequence":"additional","affiliation":[{"name":"Center for Pediatric Inflammatory Bowel Disease Division of Gastroenterology, Hepatology, and Nutrition Children's Hospital of Philadelphia Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,5]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"OrelR.Epidemiology of chronic inflammatory bowel disease in children. In: Gregoric A (ed). XV Maribor Pediatric Meeting With International Participation April 15\u201016 2005 Maribor Slovenia pp.31\u20134[in Slovene]."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200608000-00002"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MPG.0000163736.30261.82"},{"key":"e_1_2_6_5_1","volume-title":"Paediatric Gastrointestinal Disease","author":"Griffiths AM","year":"2004"},{"key":"e_1_2_6_6_1","volume-title":"Paediatric Gastrointestinal Disease","author":"Leichtner AM","year":"2004"},{"key":"e_1_2_6_7_1","volume-title":"Paediatric Gastrointestinal Disease","author":"Kirschner BS","year":"2004"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1994.tb13098.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0022-3476(03)00444-X"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.10.1432"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04309-9"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050066"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000189328.47150.bc"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2004.tb12167.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2004.tb12181.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200003000-00009"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200406001-00843"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2004.tb13091.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.30.5.618"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05915.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000256248.25547.0b"},{"key":"e_1_2_6_22_1","unstructured":"FerkoljI.Inflammatory Bowel Disease: The Clinical Problem. Paper presented at the Falk Workshop Ljubljana Slovenia May 5 2001 p 7."},{"key":"e_1_2_6_23_1","first-page":"40","article-title":"Epidemiologija kroni\u010dne vnetne \u010drevesne bolezni pri otrocih","volume":"8","author":"Orel R","year":"2004","journal-title":"Gastroenterology"},{"key":"e_1_2_6_24_1","unstructured":"Statistical Office of the Republic of Slovenia.Census of Population Household and Housing 2002.http:\/\/www.stat.si\/popis2002. Accessed March 25 2009."},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2005\/269076"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2003.tb07962.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2003.tb07963.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.25.5.534"},{"key":"e_1_2_6_29_1","first-page":"5810","article-title":"Chronic inflammatory bowel disease: an epidemiology study from eastern Denmark 1998\u20102000","volume":"164","author":"Urne FU","year":"2002","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2004.tb13150.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.1989.tb09788.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000256277.29599.70"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.08.043"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.88.11.995"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529709000184"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.74.5.460"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MPG.0b013e318164d903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T13:06:32Z","timestamp":1705583192000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MPG.0b013e318164d903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.1097\/MPG.0b013e318164d903"],"URL":"https:\/\/doi.org\/10.1097\/mpg.0b013e318164d903","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}