{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:33:59Z","timestamp":1789238039881,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aims:<\/jats:title><jats:p>Increasing use of diagnostic radiography has led to concern about the malignant potential of ionizing radiation. We aimed to quantify the cumulative effective dose (CED) from diagnostic medical imaging in children with inflammatory bowel disease (IBD) and to identify which children are at greatest risk for high amounts of image\u2010related radiation exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods:<\/jats:title><jats:p>A retrospective chart review of pediatric IBD patients seen between January 1 and May 30, 2008 was conducted. The effective dose of radiation received from all of the radiology tests performed during the course of each patient's treatment was estimated using typical effective doses and our institution's computed tomography dose index. A CED \u226550 mSv was considered high.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Complete records were available for 257 of 372 screened subjects. One hundred seventy\u2010one had Crohn disease (CD) and 86 had ulcerative colitis (UC). The mean CED was 17.56 \u00b1 15.91 mSv and was greater for children with CD than for those with UC (20.5 \u00b1 17.5 vs 11.7 \u00b1 9.9 mSv, <jats:italic>P<\/jats:italic> &lt; 0.0001). Fifteen children (5.8%) had a CED \u226550 mSv, including 14 of 171 (8.2%) with CD and 1 of 86 (1.2%) with UC (<jats:italic>P<\/jats:italic> = 0.02). In children with CD, factors associated with high CED per multivariate analysis were any IBD\u2010related surgery (odds ratio 42, 95% confidence interval 8\u2013223, <jats:italic>P<\/jats:italic> &lt; 0.0001) and platelet count (odds ratio 16, 95% confidence interval 1.5\u2013175, <jats:italic>P<\/jats:italic> = 0.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Although all doses of ionizing radiation have some malignancy\u2010inducing potential, a small but important percentage of children with IBD are exposed to particularly high doses of ionizing radiation from diagnostic tests and procedures. Physicians caring for such patients must seek to limit radiation exposure whenever possible to lessen the lifetime risk of malignancy.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e3181f57177","type":"journal-article","created":{"date-parts":[[2011,2,4]],"date-time":"2011-02-04T06:32:01Z","timestamp":1296801121000},"page":"280-285","source":"Crossref","is-referenced-by-count":42,"title":["Pediatric Inflammatory Bowel Disease and Imaging\u2010related Radiation: Are We Increasing the Likelihood of Malignancy?"],"prefix":"10.1002","volume":"52","author":[{"given":"Yonathan","family":"Fuchs","sequence":"first","affiliation":[{"name":"Division of Pediatric Gastroenterology Cohen Children's Medical Center North Shore\u2010Long Island Jewish Health System New Hyde Park USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Markowitz","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology Cohen Children's Medical Center North Shore\u2010Long Island Jewish Health System New Hyde Park USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toba","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology Cohen Children's Medical Center North Shore\u2010Long Island Jewish Health System New Hyde Park USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Kohn","sequence":"additional","affiliation":[{"name":"The Biostatistics Unit at the Feinstein Institute of Medical Research Manhasset USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"Choi\u2010Rosen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Radiology Cohen Children's Medical Center North Shore\u2010Long Island Jewish Health System New Hyde Park NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremiah","family":"Levine","sequence":"additional","affiliation":[{"name":"Division of 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