{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T21:28:26Z","timestamp":1770413306241,"version":"3.49.0"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives:<\/jats:title><jats:p>Pediatric small\u2010bowel volvulus (SBV) is a surgical emergency, and early diagnosis is difficult. We analyzed the clinical manifestations, imaging findings, and laboratory parameters in children with SBV and attempted to determine the risk factors for bowel gangrene.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods:<\/jats:title><jats:p>Forty\u2010nine children (35 boys and 14 girls) with SBV who were admitted to the hospital for a period of 13 years were enrolled. Clinical and laboratory parameters and evaluation measures included fever, abdominal pain, vomiting, bloody stool, peritoneal signs, severe dehydration, disease duration, white blood cell counts, sugar, C\u2010reactive protein (CRP), sodium, potassium, metabolic acidosis, blood urea nitrogen, and creatinine. These parameters were statistically compared between patients with and without bowel gangrene.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Thirty\u2010six patients (73.5%) were 5 years old or younger, and nearly half were younger than 1 year old. Abdominal pain and vomiting were 2 major symptoms. Malrotation was the most common cause of SBV. In univariate analysis, nonbilious vomiting, peritoneal signs, severe dehydration, leukocytosis (WBC count &gt;18,000 cells\/mm<jats:sup>3<\/jats:sup>), elevated CRP (&gt;50 mg\/dL), and hyponatremia (&lt;130 mmol\/L) were significantly associated with bowel gangrene (<jats:italic>P<\/jats:italic> &lt; 0.05). In multivariate analysis, nonbilious vomiting, leukocytosis, and elevated CRP were significantly (<jats:italic>P<\/jats:italic> &lt; 0.05) associated with bowel gangrene. The resection rate for bowel gangrene was 44.9%, and no mortality was found. Seven (14.3%) patients had postoperative complications, including short\u2010bowel syndrome (n = 2), adhesion ileus (n = 3), and intraabdominal abscess (n = 3). Seven experienced failure to thrive in later follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Specific clinical manifestations and laboratory parameters are helpful in the identification of bowel gangrene in children with SBV.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e3182201a7c","type":"journal-article","created":{"date-parts":[[2011,4,22]],"date-time":"2011-04-22T03:01:24Z","timestamp":1303441284000},"page":"417-422","source":"Crossref","is-referenced-by-count":19,"title":["Risk Factors for Intestinal Gangrene in Children With Small\u2010bowel Volvulus"],"prefix":"10.1002","volume":"53","author":[{"given":"Yu\u2010Pi","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology Chang Gung Children's Medical Center Chang Gung Memorial Hospital Chang Gung University College of Medicine Taoyuan 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Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming\u2010Wei","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Chang Gung Children's Medical Center Chang Gung Memorial Hospital Chang Gung University College of Medicine Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien\u2010Chang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Chang Gung Children's Medical Center Chang Gung Memorial Hospital Chang Gung University College of Medicine Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih\u2010Yen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Chang Gung Children's Medical Center Chang Gung Memorial Hospital Chang Gung University College of Medicine Taoyuan 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