{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T16:47:48Z","timestamp":1776185268452,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Objective:<\/jats:title><jats:p>Because capsule endoscopy (CE) avoids ionizing radiation, deep sedation, and general anesthesia, CE may be valuable in pediatrics. We report a single pediatric center's experience with the use and safety of CE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>In a retrospective review of consecutive CE studies, 284 CE studies were performed in 277 patients with a mean age of 15 (\u00b13.7) years during a 5\u2010year period. The youngest to swallow the capsule was 4.6 years old. Twenty capsules were placed. Overall, 245 (86%) patients underwent CE for suspected (184, 65%) or confirmed (61, 21%) Crohn disease (CD); 27 (9.5%) anemia or gastrointestinal bleeding; 6 (2%) polyposis; and 4 (1.4%) celiac disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Positive findings were observed in 205 (72%) of the studies, with 152 (54%) having small bowel findings. Of these, 72 (47%) were diagnostic. Gastric (95, 33%) and colonic (31, 11%) abnormalities were also identified. Five CE studies (1.8%) resulted in retention of the capsule in nonsurgical patients. A patency capsule before CE in 23 patients allowed 19 CE to proceed with only 1 retained capsule. In 65 (21%) patients, the video capsule did not enter the colon before the video's end. Of these, 36 (65%) had significant findings, including 27 (49%) documenting small bowel (SB) CD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>CE is useful to diagnose SB disease in children. Even in a study population with a high prevalence of confirmed and suspected CD, the risk of retention remains small. The patency capsule may lessen that risk. CE may identify gastric or colonic disease even when SB lesions are not present.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e31822c81fd","type":"journal-article","created":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T07:13:33Z","timestamp":1310627613000},"page":"409-413","source":"Crossref","is-referenced-by-count":53,"title":["Pediatric Capsule Endoscopy"],"prefix":"10.1002","volume":"54","author":[{"given":"Stanley A.","family":"Cohen","sequence":"first","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hagit","family":"Ephrath","sequence":"additional","affiliation":[{"name":"Given Imaging Yokneam Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffery D.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Klevens","sequence":"additional","affiliation":[{"name":"Given Imaging Yokneam Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ari","family":"Bergwerk","sequence":"additional","affiliation":[{"name":"Given Imaging Yokneam Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Liu","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinesh","family":"Patel","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bonney","family":"Reed\u2010Knight","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Stallworth","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Wakhisi","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin D.","family":"Gold","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"US Food and Drug Administration Center for Devices and Radiological Health.PC Patency System and Pillcam Platform With Pillcam SB Capsules. (510k Number K090557; Approval September 28 2009) Available at:http:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf9\/K090557.pdf. Accessed February 10 2010."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.01.016"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000252196.91707.ff"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0209-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00715-3"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2006.0114"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318160df85"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01209.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181926b01"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31818b0ac7"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3180335548"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-006-0331-9"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-825854"},{"key":"e_1_2_7_15_1","first-page":"11","article-title":"Capsule endoscopy in paediatrics: multicentric Belgian study","volume":"70","author":"Urbain D","year":"2007","journal-title":"Acta Gastroenterol Belg"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.177774"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000239737.64240.72"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31818f0a1f"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.03.025"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.09.031"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.00274.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-010-1330-2"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MPG.0b013e31822c81fd","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T12:52:12Z","timestamp":1705582332000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MPG.0b013e31822c81fd"}},"subtitle":["Review of the Small Bowel and Patency Capsules"],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1097\/MPG.0b013e31822c81fd"],"URL":"https:\/\/doi.org\/10.1097\/mpg.0b013e31822c81fd","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}