{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:49:41Z","timestamp":1790394581584,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The aim of the present study was to investigate the association between childhood and adolescent obesity, the risk of gallstones, and the potential effect modification by oral contraceptive use in girls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>For this population\u2010based cross\u2010sectional study, measured weight and height, oral contraceptive use, and diagnosis of cholelithiasis or choledocholithiasis were extracted from the electronic medical records of 510,816 patients ages 10 to 19 years enrolled in an integrated health plan, 2007\u20132009.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We identified 766 patients with gallstones. The adjusted odds ratios (95% CI) of gallstones for under\u2010\/normal\u2010weight (reference), overweight, moderate obesity, and extreme obesity in boys were 1.00, 1.46 (0.94%\u20132.27%), 1.83 (1.17%\u20132.85%), and 3.10 (1.99%\u20134.83%) and in girls were 1.00, 2.73 (2.18%\u20133.42%), 5.75 (4.62%\u20137.17%), and 7.71 (6.13%\u20139.71%), respectively (\n                      <jats:italic>P<\/jats:italic>\n                      for interaction sex \u00d7 weight class &lt;0.001). Among girls, oral contraceptive use was associated with higher odds for gallstones (odds ratio 2.00, 95% CI 1.66%\u20132.40%). Girls who used oral contraceptives were at higher odds for gallstones than their counterparts in the same weight class who did not use oral contraceptives (\n                      <jats:italic>P<\/jats:italic>\n                      for interaction weight class \u00d7 oral contraceptive use 0.023).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Due to the shift toward extreme childhood obesity, especially in minority children, pediatricians can expect to face increasing numbers of children and adolescents affected by gallstone disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/mpg.0b013e31824d256f","type":"journal-article","created":{"date-parts":[[2012,2,7]],"date-time":"2012-02-07T07:16:14Z","timestamp":1328598974000},"page":"328-333","source":"Crossref","is-referenced-by-count":107,"title":["Pediatric Obesity and Gallstone Disease"],"prefix":"10.1002","volume":"55","author":[{"given":"Corinna","family":"Koebnick","sequence":"first","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Helen","family":"Black","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy H.","family":"Porter","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Baldwin Park Medical Center Baldwin Park"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley A.","family":"Richie","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Riverside Medical Center Riverside"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Hudson","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Gililland","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Fontana Medical Center Fontana CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George F.","family":"Longstreth","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California Pasadena"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2010.02.003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.12.015"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.10.060"},{"key":"e_1_2_9_5_1","first-page":"493","article-title":"Gallbladder volume in adults, and relationship to age, sex, body mass index, and gallstones: a sonographic population study","volume":"87","author":"Palasciano G","year":"1992","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.6.1250"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.11.9.268"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.01.025"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.2012"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000187816.31213.06"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1109957"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(99)00063-X"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031049"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200203143461112"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2009.02.004"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803156"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.83.8.1113"},{"key":"e_1_2_9_18_1","doi-asserted-by":"crossref","unstructured":"KoebnickC ColemanKJ BlackMH et al.Cohort Profile: the KPSC Children's Health Study a population\u2010based study of 920 000 children and adolescents in southern California. Int J Epidemiol 2011 (Epub ahead of print).","DOI":"10.1093\/ije\/dyq252"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/17477160903268308"},{"key":"e_1_2_9_20_1","volume-title":"Obesity: Preventing and Managing the Global Epidemic","author":"World Health Organization.","year":"2000"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28335"},{"key":"e_1_2_9_22_1","first-page":"1","article-title":"2000 CDC Growth Charts for the United States: methods and development","volume":"11","author":"Kuczmarski RJ","year":"2002","journal-title":"Vital Health Stat"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-10-316"},{"key":"e_1_2_9_24_1","unstructured":"Bureau of the Census.Census 2000 surname list.http:\/\/wwwcensusgov\/genealogy\/www\/data\/2000surnames\/index.html. Washington DC;2009."},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2006.00551.x"},{"key":"e_1_2_9_26_1","volume-title":"Technical working paper no.13","author":"Word DL"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.1.38"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.076133"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2009.194"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510250623"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2006.05.004"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1980.01380010054010"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198908313210902"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510260401"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840070520"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01550973"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.288.6424.1113"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2009.06.006"},{"key":"e_1_2_9_39_1","first-page":"137","article-title":"Gallstones and ethnicity in the Americas","volume":"12","author":"Everhart JE","year":"2001","journal-title":"J Assoc Acad Minor Phys"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01949.x"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(21)00536-7"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MPG.0b013e31824d256f","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T07:51:30Z","timestamp":1705564290000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MPG.0b013e31824d256f"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1097\/MPG.0b013e31824d256f"],"URL":"https:\/\/doi.org\/10.1097\/mpg.0b013e31824d256f","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}