{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T22:34:42Z","timestamp":1782772482590,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives:<\/jats:title><jats:p>Gastric motor abnormalities have been reported in adults with irritable bowel syndrome (IBS), commonly in constipation\u2010predominant IBS (IBS\u2010C); however, such studies are uncommon in children. Furthermore, differences of gastric motility have not been studied in children with different IBS subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Seventy\u2010six children (33 [43%] boys, age 4\u201314 years, mean 7.9 years, SD 3.0 years) fulfilling Rome III criteria for IBS and 20 healthy controls (8 [40%] boys, age 4\u201314 years, mean 8.4 years, SD 3.0 years) were recruited (diarrhea\u2010predominant IBS = 21, IBS\u2010C = 31, mixed IBS = 19, and unsubtyped IBS = 5). Liquid gastric emptying rate (GER) and antral motility were assessed using an ultrasound method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Average GER (43.8% vs 66.2% in controls), amplitude of antral contractions (56.4% vs 89%), and antral motility index (5.1 vs 8.3) were lower and fasting antral area (1.6 vs 0.6) was higher in patients with IBS (<jats:italic>P<\/jats:italic> &lt; 0.0001). Frequency of antral contractions F (8.9 vs 9.3) did not show a significant difference. Patients exposed to stressful events had a significantly lower GER, compared to those not exposed to such events (<jats:italic>P<\/jats:italic> = 0.03). Gastric motility parameters had no correlation with severity of symptoms. GER (42.6%, 46.3%, 39.6%), fasting antral area (1.4 cm<jats:sup>2<\/jats:sup>, 1.8 cm<jats:sup>2<\/jats:sup>, 1.8 cm<jats:sup>2<\/jats:sup>), amplitude of antral contractions (53%, 58.9%, 51.8%), frequency of antral contractions (8.7, 8.9, 9.2), and antral motility index (4.7, 5.3, 4.8) were not different among diarrhea\u2010predominant IBS, IBS\u2010C, and mixed IBS (<jats:italic>P<\/jats:italic> &gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>GER and antral motility parameters were significantly impaired in children with IBS compared with controls. GER and antral motility parameters were not different between IBS subtypes.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e31827f7a3d","type":"journal-article","created":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T09:17:05Z","timestamp":1354094225000},"page":"443-448","source":"Crossref","is-referenced-by-count":42,"title":["Ultrasonographic Assessment of Liquid Gastric Emptying and Antral Motility According to the Subtypes of Irritable Bowel Syndrome in Children"],"prefix":"10.1002","volume":"56","author":[{"given":"Niranga M.","family":"Devanarayana","sequence":"first","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Thalagolla Road Ragama Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaman","family":"Rajindrajith","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine University of Kelaniya Thalagolla Road Ragama Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrika","family":"Bandara","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Thalagolla Road Ragama Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayani","family":"Shashiprabha","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Thalagolla Road Ragama Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc A.","family":"Benninga","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition Emma Children's Hospital Academic Medical Center Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.08.063"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(96)70246-9"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2764"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmq039"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3182296033"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v9.i10.2293"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.07062.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002590050404"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529209165425"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.030049"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2012.18.3.298"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.67.5.613"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005493123557"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01871.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05529.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.061"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2000.02251.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529409094860"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01295904"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-003-0954-1"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e318181b42f"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.059790"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1635-9"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01299804"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529209000100"},{"key":"e_1_2_8_27_1","first-page":"A1594","article-title":"Ultrasonography is a valuble method to assess the volume of gastric emptying","volume":"92","author":"Ricci R","year":"1987","journal-title":"Gastroenterology"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(88)80007-6"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237134"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.SMJ.0000100265.49370.AD"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2008.01.001"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181d33b7d"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmp077"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmm114"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.01.032"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.280.2.G173"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.280.4.G519"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MPG.0b013e31827f7a3d","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T15:17:57Z","timestamp":1705591077000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MPG.0b013e31827f7a3d"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1097\/MPG.0b013e31827f7a3d"],"URL":"https:\/\/doi.org\/10.1097\/mpg.0b013e31827f7a3d","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}