{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T06:15:54Z","timestamp":1789884954401,"version":"4.0.1"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008352","name":"Stiftelsen Samariten","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008352","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives:<\/jats:title><jats:p>A sharp increase in paediatric (younger than 16 years) inflammatory bowel disease (IBD) incidence was observed in northern Stockholm County, Sweden, in 1990\u20132001. The increasing incidence was primarily explained by a rising incidence of Crohn disease (CD). Here, we present an update on the trends in incidence of paediatric IBD, 2002\u20132007.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>Medical records of all children diagnosed as having suspected IBD in northern Stockholm County, 2002\u20132007, were scrutinised using defined diagnostic criteria. Disease extension, localisation, and behaviour at diagnosis were classified within the framework of the Paris classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result:<\/jats:title><jats:p>A total of 133 children were diagnosed as having IBD 2002\u20132007 corresponding to a sex\u2010 and age\u2010standardised incidence (per 10<jats:sup>5<\/jats:sup> person\u2010years) for paediatric IBD of 12.8 (95% CI 10.8\u201315.2). The standardised incidence was 9.2 (95% CI 7.5\u201311.2) for CD and 2.8 (95% CI 1.9\u20134.0) for ulcerative colitis (UC). A significant increasing incidence of UC (<jats:italic>P<\/jats:italic> &lt; 0.05) was observed during the study period. No temporal trend was observed for the incidence of CD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>The incidence rate of paediatric IBD in northern Stockholm was significantly higher in 2002\u20132007 than that observed in our earlier study covering 1990\u20132001. The former sharp increase in incidence of paediatric CD seems, however, to have levelled out, although at a higher rate than reported from most other regions in the world. Although CD was still predominant, the observed increase in incidence of UC during the study period is notable.<\/jats:p><\/jats:sec>","DOI":"10.1097\/mpg.0b013e31828f21b4","type":"journal-article","created":{"date-parts":[[2013,3,2]],"date-time":"2013-03-02T14:40:05Z","timestamp":1362235205000},"page":"29-34","source":"Crossref","is-referenced-by-count":79,"title":["Increasing Incidence of Paediatric Inflammatory Bowel Disease in Northern Stockholm County, 2002\u20132007"],"prefix":"10.1002","volume":"57","author":[{"given":"Petter","family":"Malmborg","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Astrid Lindgren Children's Hospital Karolinska University Hospital Karolinska Institutet \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Grahnquist","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Astrid Lindgren Children's Hospital Karolinska University Hospital Karolinska Institutet \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Lindholm","sequence":"additional","affiliation":[{"name":"Department of Oncology\u2010Pathology Karolinska University Hospital Karolinska Institutet \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics \u00d6rebro University Hospital &amp; \u00d6rebro University \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Hildebrand","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Astrid Lindgren Children's Hospital Karolinska University Hospital Karolinska Institutet \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21349"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.10.1432"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21550"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.188383"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(03)00385-8"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11582"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21283"},{"key":"e_1_2_7_9_1","first-page":"18","article-title":"Geographical variability and environmental risk factors in inflammatory bowel disease","volume":"18","author":"Ng SC","year":"2013","journal-title":"Gut"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1994.tb13098.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31805563f3"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21493"},{"key":"e_1_2_7_13_1","volume-title":"The Design and Analysis of Cohort Studies","author":"Breslow NE","year":"1987"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780100317"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.01.038"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00603.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520802647434"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2008.01.006"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200608000-00002"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21654"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200402001-00007"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04309-9"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MPG.0000162479.74277.86"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i1.75"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318164d903"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21797"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2011-300651"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.079"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0022-3476(03)00444-X"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/MPG.0b013e31828f21b4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T12:53:40Z","timestamp":1705582420000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/MPG.0b013e31828f21b4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1097\/MPG.0b013e31828f21b4"],"URL":"https:\/\/doi.org\/10.1097\/mpg.0b013e31828f21b4","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}