{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:39:28Z","timestamp":1787503168194,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1097\/mph.0000000000000005","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T05:05:54Z","timestamp":1383282354000},"page":"e448-e451","source":"Crossref","is-referenced-by-count":12,"title":["Response of Subependymal Giant Cell Astrocytoma With Spinal Cord Metastasis to Everolimus"],"prefix":"10.1097","volume":"36","author":[{"given":"Dolly","family":"Aguilera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Flamini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Mazewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Schniederjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Boydston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert C.","family":"Castellino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobey J.","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-26-20210227","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/0031302410001671975","article-title":". Subependymal giant cell astrocytoma: a clinicopathological study of 23 cases with special emphasis on proliferative markers and expression of p53 and retinoblastoma gene proteins.","volume":"36","author":"Sharma","year":"2004","journal-title":"Pathology"},{"key":"R2-26-20210227","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1212\/01.WNL.0000142039.14522.1A","article-title":"Subependymal giant cell tumors in tuberous sclerosis complex.","volume":"63","author":"Goh","year":"2004","journal-title":"Neurology"},{"key":"R3-26-20210227","doi-asserted-by":"crossref","first-page":"299","DOI":"10.2165\/00148581-200810050-00004","article-title":"Current management of tuberous sclerosis complex.","volume":"10","author":"Krueger","year":"2008","journal-title":"Paediatr Drugs"},{"key":"R4-26-20210227","doi-asserted-by":"crossref","first-page":"287","DOI":"10.2176\/nmc.38.287","article-title":". Glioblastoma following radiotherapy in a patient with tuberous sclerosis.","volume":"38","author":"Matsumura","year":"1998","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"R5-26-20210227","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/S0025-6196(12)61196-3","article-title":". Causes of death in patients with tuberous sclerosis.","volume":"66","author":"Shepherd","year":"1991","journal-title":"Mayo Clin Proc"},{"key":"R6-26-20210227","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1056\/NEJMra055323","article-title":"The tuberous sclerosis complex.","volume":"355","author":"Crino","year":"2006","journal-title":"N Engl J Med"},{"key":"R7-26-20210227","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(08)61279-9","article-title":"Tuberous sclerosis.","volume":"372","author":"Curatolo","year":"2008","journal-title":"Lancet"},{"key":"R8-26-20210227","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1002\/ana.21331","article-title":". Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.","volume":"63","author":"Zeng","year":"2008","journal-title":"Ann Neurol"},{"key":"R9-26-20210227","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nm1788","article-title":". Reversal of learning deficits in a Tsc2 mouse model of tuberous sclerosis.","volume":"14","author":"Ehninger","year":"2008","journal-title":"Nat Med"},{"key":"R10-26-20210227","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/ana.20784","article-title":". Rapamycin causes regression of astrocytomas in tuberous sclerosis complex.","volume":"59","author":"Franz","year":"2006","journal-title":"Ann Neurol"},{"key":"R11-26-20210227","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/pbc.22298","article-title":". Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors.","volume":"54","author":"Lam","year":"2010","journal-title":"Pediatr Blood Cancer"},{"key":"R12-26-20210227","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1056\/NEJMoa1001671","article-title":". Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.","volume":"363","author":"Krueger","year":"2010","journal-title":"N Engl J Med"},{"key":"R13-26-20210227","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1227\/00006123-199106000-00013","article-title":". Subependymal giant cell astrocytoma: a clinical, pathological, and flow cytometric study.","volume":"28","author":"Shepherd","year":"1991","journal-title":"Neurosurgery"},{"key":"R14-26-20210227","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s00381-002-0700-2","article-title":". Subependymal giant cell astrocytoma in children with tuberous sclerosis.","volume":"19","author":"Cuccia","year":"2003","journal-title":"Childs Nerv Syst"},{"key":"R16-26-20210227","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3171\/2009.3.PEDS08225","article-title":". Extraventricular subependymal giant cell tumor in a child with tuberous sclerosis complex.","volume":"4","author":"Bollo","year":"2009","journal-title":"J Neurosurg Pediatr"},{"key":"R17-26-20210227","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1227\/00006123-198405000-00009","article-title":". Connatal brain tumors in patients with tuberous sclerosis.","volume":"14","author":"Painter","year":"1984","journal-title":"Neurosurgery"},{"key":"R18-26-20210227","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1038\/sj.bjp.0704142","article-title":". Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.","volume":"133","author":"Serkova","year":"2001","journal-title":"Br J Pharmacol"},{"key":"R19-26-20210227","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0140-6736(12)61134-9","article-title":". Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial.","volume":"381","author":"Franz","year":"2012","journal-title":"Lancet"}],"container-title":["Journal of Pediatric Hematology\/Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MPH.0000000000000005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T23:43:45Z","timestamp":1620949425000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00043426-201410000-00026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1097\/mph.0000000000000005","relation":{},"ISSN":["1077-4114"],"issn-type":[{"value":"1077-4114","type":"print"}],"subject":[],"published":{"date-parts":[[2014,10]]}}}