{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T15:50:22Z","timestamp":1780933822294,"version":"3.54.1"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>Infantile pyknocytosis is a rare and self-limiting cause of hemolytic anemia in neonates. It can result in severe anemia and hyperbilirubinemia. The pathogenesis is unknown: a genetic origin has been discussed; however, based on the current literature it is not clear which genetic mutations should be considered. We present a case of a premature twin, in whom genetic screening was performed. Genetic mutations in 46 genes associated with hereditary hemolytic anemia and dyserythropoietic anemia were tested. No mutations were found. In infantile pyknocytosis, a genetic defect in these genes is unlikely.<\/jats:p>","DOI":"10.1097\/mph.0000000000002004","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T19:04:56Z","timestamp":1606244696000},"page":"e1037-e1039","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Infantile Pyknocytosis in a Premature Dichorionic Diamniotic Twin"],"prefix":"10.1097","volume":"43","author":[{"given":"Mandy E.","family":"Spoorenberg","sequence":"first","affiliation":[{"name":"Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate E.","family":"Wachters-Hagedoorn","sequence":"additional","affiliation":[{"name":"Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"van Wijk","sequence":"additional","affiliation":[{"name":"Central Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques B.","family":"de Kok","sequence":"additional","affiliation":[{"name":"Clinical Chemistry, Deventer Hospital, Deventer"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"R1-20250804","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1001\/archpedi.1959.02070020229009","article-title":"Infantile pyknocytosis; 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