{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:05:42Z","timestamp":1786118742388,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1097\/mph.0b013e3180335043","type":"journal-article","created":{"date-parts":[[2007,3,12]],"date-time":"2007-03-12T02:53:11Z","timestamp":1173667991000},"page":"183-186","source":"Crossref","is-referenced-by-count":15,"title":["Acute Encephalopathy and Cerebral Vasospasm After Multiagent Chemotherapy Including PEG-asparaginase and Intrathecal Cytarabine for the Treatment of Acute Lymphoblastic Leukemia"],"prefix":"10.1097","volume":"29","author":[{"given":"Catherine M.","family":"Pound","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel L.","family":"Keene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Udjus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Humphreys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna L.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210227","first-page":"1014","article-title":"High-dose cytarabine neurotoxicity: MR findings during the acute phase","volume":"14","author":"Vaughn","year":"1993","journal-title":"Am J Neuroradiol"},{"key":"R2-12-20210227","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000050797","article-title":"MR findings in Balint's syndrome, following intrathecal methotrexate and cytarabine in adult acute lymphoblastic leukemia","volume":"46","author":"Hollinger","year":"2001","journal-title":"Eur Neurol"},{"key":"R3-12-20210227","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1200\/JCO.1996.14.10.2803","article-title":"Intensive oral MTX protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia","volume":"14","author":"Winick","year":"1996","journal-title":"J Clin Oncol"},{"key":"R4-12-20210227","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0140-6736(86)92304-4","article-title":"Acute encephalopathy and hyperammonaemia complicating treatment of acute lymphoblastic leukaemia with asparaginase","volume":"1","author":"Leonard","year":"1986","journal-title":"Lancet"},{"key":"R5-12-20210227","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3109\/08880019309029506","article-title":"Cerebrovascular complications of L-asparaginase therapy in children with leukemia: aphasia and other neuropsychological deficits","volume":"10","author":"Kingma","year":"1993","journal-title":"Pediatr Hematol Oncol"},{"key":"R6-12-20210227","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1002\/1097-0142(19801001)46:7<1548::AID-CNCR2820460709>3.0.CO;2-7","article-title":"Thrombotic and hemorrhagic strokes complicating early therapy for childhood acute lymphoblastic leukemia","volume":"46","author":"Priest","year":"1980","journal-title":"Cancer"},{"key":"R7-12-20210227","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0022-3476(82)80536-2","article-title":"The effect of L-asparaginase on antithrombin, plasminogen, and plasma coagulation during therapy for acute lymphoblastic leukemia","volume":"100","author":"Priest","year":"1982","journal-title":"J Pediatr"},{"key":"R8-12-20210227","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.jhep.2004.06.011","article-title":"Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow","volume":"41","author":"Jalan","year":"2004","journal-title":"J Hepatol"},{"key":"R9-12-20210227","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1200\/JCO.1999.17.9.2804","article-title":"Contribution of single-photon emission computed tomography in the diagnosis and follow-up of CNS toxicity of a cytarabine-containing regimen in pediatric leukemia","volume":"17","author":"Vera","year":"1999","journal-title":"J Clin Oncol"},{"key":"R10-12-20210227","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1200\/JCO.1991.9.4.679","article-title":"Cytarabine and neurologic toxicity","volume":"9","author":"Baker","year":"1991","journal-title":"J Clin Oncol"},{"key":"R11-12-20210227","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.nic.2005.08.011","article-title":"Diffusion-weighted imaging in acute stroke. Diffusion-weighted imaging in acute stroke","volume":"15","author":"Schaefer","year":"2005","journal-title":"Neuroimaging Clin N Am"},{"key":"R12-12-20210227","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1212\/01.WNL.0000042095.49520.1E","article-title":"Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm","volume":"60","author":"Henderson","year":"2003","journal-title":"Neurology"}],"container-title":["Journal of Pediatric Hematology\/Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MPH.0b013e3180335043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:36:24Z","timestamp":1786034184000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00043426-200703000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/mph.0b013e3180335043","relation":{},"ISSN":["1077-4114"],"issn-type":[{"value":"1077-4114","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}