{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:25:55Z","timestamp":1786119955605,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1097\/mph.0b013e318205e230","type":"journal-article","created":{"date-parts":[[2011,5,13]],"date-time":"2011-05-13T05:07:35Z","timestamp":1305263255000},"page":"e198-e201","source":"Crossref","is-referenced-by-count":12,"title":["Transformation of Juvenile Pilocytic Astrocytoma to Anaplastic Pilocytic Astrocytoma in Patients With Neurofibromatosis Type I"],"prefix":"10.1097","volume":"33","author":[{"given":"Katherine B.","family":"Peters","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Cummings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridharan","family":"Gururangan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-26-20210227","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1542\/peds.2007-3204","article-title":"Neurofibromatosis type 1 revisited.","volume":"123","author":"Williams","year":"2009","journal-title":"Pediatrics"},{"key":"R2-26-20210227","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/NEN.0b013e318165eb75","article-title":"Gliomas in neurofibromatosis type 1: a clinicopathologic study of 100 patients.","volume":"67","author":"Rodriguez","year":"2008","journal-title":"J Neuropathol Exp Neurol"},{"key":"R3-26-20210227","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3171\/jns.1988.69.2.0171","article-title":"Treatment results of juvenile pilocytic astrocytoma.","volume":"69","author":"Wallner","year":"1988","journal-title":"J Neurosurg"},{"key":"R4-26-20210227","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/1097-0142(19930801)72:3<856::AID-CNCR2820720335>3.0.CO;2-K","article-title":"Astrocytomas of the cerebellum: a comparative clinicopathologic study of pilocytic and diffuse astrocytomas.","volume":"72","author":"Hayostek","year":"1993","journal-title":"Cancer"},{"key":"R7-26-20210227","first-page":"68","article-title":"Development of anaplastic changes in low-grade astrocytomas of childhood.","volume":"34","author":"Dirks","year":"1994","journal-title":"Neurosurgery"},{"key":"R8-26-20210227","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1177\/088307389400900317","article-title":"The significance of atypia and histologic malignancy in pilocytic astrocytoma of the cerebellum: a clinicopathologic and flow cytometric study.","volume":"9","author":"Tomlinson","year":"1994","journal-title":"J Child Neurol"},{"key":"R9-26-20210227","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/PAS.0b013e3181c75238","article-title":"Anaplasia in pilocytic astrocytoma predicts aggressive behavior.","volume":"34","author":"Rodriguez","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"R10-26-20210227","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1001\/archopht.119.4.516","article-title":"Spontaneous regression of optic gliomas: thirteen cases documented by serial neuroimaging.","volume":"119","author":"Parsa","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"R11-26-20210227","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1159\/000028917","article-title":"Spontaneous regression of low-grade astrocytomas in childhood.","volume":"32","author":"Schmandt","year":"2000","journal-title":"Pediatr Neurosurg"},{"key":"R12-26-20210227","doi-asserted-by":"crossref","first-page":"2968","DOI":"10.1200\/JCO.2003.01.017","article-title":"Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents.","volume":"21","author":"Bowers","year":"2003","journal-title":"J Clin Oncol"},{"key":"R13-26-20210227","first-page":"2725","article-title":"Multifaceted resistance of gliomas to temozolomide.","volume":"8","author":"Bocangel","year":"2002","journal-title":"Clin Cancer Res"},{"key":"R14-26-20210227","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s00280-003-0660-6","article-title":"Role of mismatch repair in the induction of chromosomal aberrations and sister chromatid exchanges in cells treated with different chemotherapeutic agents.","volume":"52","author":"Vernole","year":"2003","journal-title":"Cancer Chemother Pharmacol"},{"key":"R15-26-20210227","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1158\/0008-5472.CAN-06-0127","article-title":"A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.","volume":"66","author":"Hunter","year":"2006","journal-title":"Cancer Res"},{"key":"R16-26-20210227","doi-asserted-by":"crossref","first-page":"4622","DOI":"10.1158\/1078-0432.CCR-08-3012","article-title":"MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.","volume":"15","author":"Yip","year":"2009","journal-title":"Clin Cancer Res"},{"key":"R17-26-20210227","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1158\/1078-0432.CCR-06-2149","article-title":"Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide l treatment.","volume":"13","author":"Cahill","year":"2007","journal-title":"Clin Cancer Res"}],"container-title":["Journal of Pediatric Hematology\/Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MPH.0b013e318205e230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:30:23Z","timestamp":1786044623000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00043426-201107000-00026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/mph.0b013e318205e230","relation":{},"ISSN":["1077-4114"],"issn-type":[{"value":"1077-4114","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}