{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:43:46Z","timestamp":1787010226581,"version":"build-2736575974"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>\n                    The aim of the study is to examine high-intensity interval training (HIIT) programs and a moderate-intensity continuous training (MICT) program, which are frequently used in cardiac rehabilitation programs in terms of their effects on the functional capacity and quality of life of patients with coronary artery disease (CAD). The study included 20 patients with CAD (mean age, 60.95 \u00b1 5.08 years) who had undergone revascularization surgery. The participants were randomized into HIIT-short, HIIT-long, and MICT groups. All the groups participated in a 24-session exercise-based cardiac rehabilitation program. The participants\u2019 exercise capacity was evaluated using the maximal exercise test and estimated VO\n                    <jats:sub>2max<\/jats:sub>\n                    values, functional capacity using the 6-min walk test (6MWT), and quality of life using the Short Form-36 survey and MacNew Heart Disease Health-related Quality of Life (MacNew) questionnaire. It was determined that the estimated VO\n                    <jats:sub>2max<\/jats:sub>\n                    values statistically significantly improved after treatment (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.05), and both HIIT groups were superior to the MICT group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.05). Only the HIIT groups achieved the minimal clinically important difference in the 6MWT distance. After treatment, only the MICT group had a statistically significant improvement in quality of life. There was no statistically significant difference between the groups in relation to the improvement in the 6MWT distance and quality of life (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &gt; 0.05). The results of our study showed that both HIIT programs were superior to MICT in improving the maximal exercise capacity of patients with CAD, and the three programs had a similar effect on quality of life.\n                  <\/jats:p>","DOI":"10.1097\/mrr.0000000000000524","type":"journal-article","created":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T06:00:48Z","timestamp":1645509648000},"page":"168-175","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Which high-intensity interval training program is more effective in patients with coronary artery disease?"],"prefix":"10.1097","volume":"45","author":[{"given":"Ismail","family":"Okur","sequence":"first","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Kutahya Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cihan Caner","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Kutahya Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Yaman","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Kutahya Health Sciences University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taner","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Kutahya Health Sciences University, Kutahya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,2,21]]},"reference":[{"key":"R1-20250525","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/S0140-6736(17)32152-9","article-title":"Global, regional, and national age-sex specific mortality for 264 causes of death, 1980\u20132016: a systematic analysis for the Global Burden of Disease Study 2016.","volume":"390","author":"Naghavi","year":"2017","journal-title":"Lancet"},{"key":"R2-20250525","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1093\/eurheartj\/ehw334","article-title":"Cardiovascular disease in Europe: epidemiological update 2016.","volume":"37","author":"Townsend","year":"2016","journal-title":"Eur Heart J"},{"key":"R3-20250525","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.recesp.2013.10.003","article-title":"The epidemiology of coronary heart disease.","volume":"67","author":"Ferreira-Gonz\u00e1lez","year":"2014","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"R4-20250525","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1016\/j.amjcard.2019.01.008","article-title":"Benefits and risks of high-intensity interval training in patients with coronary artery disease.","volume":"123","author":"Quindry","year":"2019","journal-title":"Am J Cardiol"},{"key":"R5-20250525","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1161\/01.CIR.0000091080.57509.E9","article-title":"Exercise capacity and the risk of death in women: the St James Women Take Heart Project.","volume":"108","author":"Gulati","year":"2003","journal-title":"Circulation"},{"key":"R6-20250525","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1023\/A:1008960308011","article-title":"Social support and quality of life in patients with coronary artery disease.","volume":"9","author":"Bosworth","journal-title":"Qual Life Res"},{"key":"R7-20250525","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s12471-013-0467-y","article-title":"Exercise-based cardiac rehabilitation in patients with coronary heart disease: a practice guideline.","volume":"21","author":"Achttien","year":"2013","journal-title":"Neth Heart J"},{"key":"R9-20250525","first-page":"233","article-title":"High-intensity interval training dosage for heart failure and coronary artery disease cardiac rehabilitation. 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