{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:28:05Z","timestamp":1788362885122,"version":"build-2803163510"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","funder":[{"name":"Peter Jay Sharp Foundation"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Acute inpatient rehabilitation is crucial for improving mobility and balance for individuals with stroke. A potentially important factor in the recovery of mobility and balance is cognition. The purpose of this study was to determine the effect of cognition on mobility and balance in acute stroke rehabilitation. This was a longitudinal cohort study based on an inpatient rehabilitation unit at a large academic medical center. Participants were individuals with stroke admitted to acute rehabilitation after an acute care hospital stay (<jats:italic toggle=\"yes\">N<\/jats:italic>\u2005=\u2005281). Demographic data and predictor variables were collected on admission to the unit. Outcomes were collected at discharge from the unit. Multiple regression analyses were used to determine the associations between cognition (Montreal Cognitive Assessment) on mobility (Functional Independence Measure mobility subscale) and balance (Berg Balance Scale). Subtests from the Montreal Cognitive Assessment were also examined to determine if specific dimensions of cognition could predict balance after controlling for covariates. Dominance analysis was used to determine the relative importance of baseline predictors. In separate models, cognition was a significant predictor of mobility (<jats:italic toggle=\"yes\">B<\/jats:italic>\u2005=\u20050.19) and balance (<jats:italic toggle=\"yes\">B<\/jats:italic>\u2005=\u20050.28) at discharge after adjusting for admission mobility and balance, as well as age, sex, and length of stay. The most important predictors in both models were baseline mobility and balance, but cognition contributed to the models independently of baseline scores. Cognition was generally more important than age and sex while about equally important as length of stay. In separate models, the visuospatial\/executive (<jats:italic toggle=\"yes\">B<\/jats:italic>\u2005=\u20050.42) and the delayed recall (<jats:italic toggle=\"yes\">B<\/jats:italic>\u2005=\u20050.37) subtests were also significant predictors of mobility. The models\u2019 most important predictors were baseline mobility and balance scores. Cognition is a clinically relevant predictor of mobility and balance in acute stroke rehabilitation. Specific dimensions of cognition, such as executive function, visuospatial function, and delayed recall, may be especially important. Cognitive challenges and meta-cognitive strategies should be included in mobility and balance tasks when possible. Studies that evaluate the efficacy of dual-task training and meta-cognitive approaches are needed.<\/jats:p>","DOI":"10.1097\/mrr.0000000000000648","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T13:00:08Z","timestamp":1730206808000},"page":"31-39","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Contribution of cognitive status on admission to mobility and balance at discharge from acute rehabilitation for stroke"],"prefix":"10.1097","volume":"48","author":[{"given":"Marc","family":"Campo","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Weill Cornell Medicine, New York"},{"name":"School of Health and Natural Sciences, Mercy University, Dobbs Ferry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Toglia","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Weill Cornell Medicine, New York"},{"name":"School of Health and Natural Sciences, Mercy University, Dobbs Ferry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Jaywant","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Weill Cornell Medicine, New York"},{"name":"New York-Presbyterian Hospital\/Weill Cornell Medical Center"},{"name":"Department of Psychiatry, Weill Cornell Medicine, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"O\u2019Dell","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Weill Cornell Medicine, New York"},{"name":"New York-Presbyterian Hospital\/Weill Cornell Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"R1-20250206","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.apmr.2012.09.033","article-title":"Does postacute care site matter? A longitudinal study assessing functional recovery after a stroke.","volume":"94","author":"Chan","year":"2013","journal-title":"Arch Phys Med Rehabil"},{"key":"R2-20250206","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1161\/STROKEAHA.120.029678","article-title":"Comprehensive stroke care and outcomes: time for a paradigm shift.","volume":"52","author":"Duncan","year":"2021","journal-title":"Stroke"},{"key":"R3-20250206","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1161\/STROKEAHA.117.018058","article-title":"Development and validation of a predictive model for functional outcome after stroke rehabilitation: the Maugeri model.","volume":"48","author":"Scrutinio","year":"2017","journal-title":"Stroke"},{"key":"R4-20250206","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1002\/rnj.218","article-title":"Length of stay at inpatient rehabilitation facility and stroke patient outcomes.","volume":"41","author":"Camicia","year":"2016","journal-title":"Rehabil Nurs"},{"key":"R5-20250206","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1161\/STROKEAHA.116.015790","article-title":"Predicting recovery potential for individual stroke patients increases rehabilitation efficiency.","volume":"48","author":"Stinear","year":"2017","journal-title":"Stroke"},{"key":"R6-20250206","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3109\/09638288.2014.963706","article-title":"A systematic review of studies reporting multivariable models to predict functional outcomes after post-stroke inpatient rehabilitation.","volume":"37","author":"Meyer","year":"2015","journal-title":"Disabil Rehabil"},{"key":"R7-20250206","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1161\/STROKEAHA.114.007392","article-title":"Measure of functional independence dominates discharge outcome prediction after inpatient rehabilitation for stroke.","volume":"46","author":"Brown","year":"2015","journal-title":"Stroke"},{"key":"R8-20250206","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1053\/apmr.2002.31203","article-title":"Mobility status during inpatient rehabilitation: a comparison of patients with stroke and traumatic brain injury.","volume":"83","author":"Eng","year":"2002","journal-title":"Arch Phys Med Rehabil"},{"key":"R9-20250206","doi-asserted-by":"crossref","first-page":"105627","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.105627","article-title":"Prediction of balance after inpatient rehabilitation in stroke subjects with severe balance alterations at the admission.","volume":"30","author":"Gath","year":"2021","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"R10-20250206","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/MRR.0000000000000552","article-title":"Cognitive impairment predicts engagement in inpatient stroke rehabilitation.","volume":"45","author":"Lowder","year":"2022","journal-title":"Int J Rehabil Res"},{"key":"R11-20250206","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1017\/S1355617718000085","article-title":"Clinical predictors of engagement in inpatient rehabilitation among stroke survivors with cognitive deficits: an exploratory study.","volume":"24","author":"Kringle","year":"2018","journal-title":"J Int Neuropsychol Soc"},{"key":"R12-20250206","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.humov.2018.03.010","article-title":"Prefrontal over-activation during walking in people with mobility deficits: interpretation and functional implications.","volume":"59","author":"Hawkins","year":"2018","journal-title":"Hum Mov Sci"},{"key":"R13-20250206","doi-asserted-by":"crossref","first-page":"246","DOI":"10.3389\/fnhum.2015.00246","article-title":"Automaticity of walking: functional significance, mechanisms, measurement and rehabilitation strategies.","volume":"9","author":"Clark","year":"2015","journal-title":"Front Hum Neurosci"},{"key":"R14-20250206","doi-asserted-by":"crossref","first-page":"734","DOI":"10.5535\/arm.2017.41.5.734","article-title":"The characteristics of cognitive impairment and their effects on functional outcome after inpatient rehabilitation in subacute stroke patients.","volume":"41","author":"Park","year":"2017","journal-title":"Ann Rehabil Med"},{"key":"R15-20250206","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/MRR.0000000000000561","article-title":"Stroke impairment, balance, and cognitive status on admission predict walking independence up to 90 days post-stroke but their contributions change over time.","volume":"46","author":"Hiratsuka","year":"2023","journal-title":"Int J Rehabil Res"},{"key":"R16-20250206","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1161\/STROKEAHA.120.032345","article-title":"Prediction of independent walking in people who are nonambulatory early after stroke: a systematic review.","volume":"52","author":"Preston","year":"2021","journal-title":"Stroke"},{"key":"R17-20250206","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3109\/09638288.2015.1035460","article-title":"Factors associated with community ambulation in chronic stroke.","volume":"38","author":"Durcan","year":"2016","journal-title":"Disabil Rehabil"},{"key":"R18-20250206","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap) \u2013 a metadata-driven methodology and workflow process for providing translational research informatics support.","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"key":"R19-20250206","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1161\/STROKEAHA.114.004590","article-title":"Use of Montreal Cognitive Assessment in patients with stroke.","volume":"45","author":"Chiti","year":"2014","journal-title":"Stroke"},{"key":"R20-20250206","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s10072-018-3254-0","article-title":"Diagnostic test accuracy of the Montreal Cognitive Assessment in the detection of post-stroke cognitive impairment under different stages and cutoffs: a systematic review and meta-analysis.","volume":"39","author":"Shi","year":"2018","journal-title":"Neurol Sci"},{"key":"R21-20250206","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2340\/16501977-1930","article-title":"Screening for cognitive impairment after stroke: a systematic review of psychometric properties and clinical utility.","volume":"47","author":"Burton","year":"2015","journal-title":"J Rehabil Med"},{"key":"R22-20250206","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.apmr.2019.08.474","article-title":"Subgroups defined by the Montreal Cognitive Assessment differ in functional gain during acute inpatient stroke rehabilitation.","volume":"101","author":"Jaywant","year":"2020","journal-title":"Arch Phys Med Rehabil"},{"key":"R23-20250206","doi-asserted-by":"crossref","first-page":"2517658","DOI":"10.1155\/2019\/2517658","article-title":"Responsiveness, minimal clinically important difference, and validity of the MoCA in stroke rehabilitation.","volume":"2019","author":"Wu","year":"2019","journal-title":"Occup Ther Int"},{"key":"R24-20250206","doi-asserted-by":"crossref","first-page":"559","DOI":"10.2522\/ptj.20070205","article-title":"Usefulness of the Berg Balance Scale in stroke rehabilitation: a systematic review.","volume":"88","author":"Blum","year":"2008","journal-title":"Phys Ther"},{"key":"R25-20250206","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3389\/fams.2018.00064","article-title":"Continuous predictors of pretest-posttest change: highlighting the impact of the regression artifact.","volume":"4","author":"Farmus","year":"2019","journal-title":"Front Appl Math Stat"},{"key":"R26-20250206","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1177\/1536867X211025837","article-title":"Determining relative importance in Stata using dominance analysis: domin and domme.","volume":"21","author":"Luchman","year":"2021","journal-title":"Stata J"},{"key":"R27-20250206","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1038\/nprot.2006.390","article-title":"Administration and interpretation of the trail making test.","volume":"1","author":"Harvey","year":"2006","journal-title":"Nat Protoc"},{"key":"R28-20250206","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3389\/fnagi.2017.00153","article-title":"Gait change is associated with cognitive outcome after an acute ischemic stroke.","volume":"9","author":"Sagnier","year":"2017","journal-title":"Front Aging Neurosci"},{"key":"R29-20250206","doi-asserted-by":"crossref","first-page":"e0281212","DOI":"10.1371\/journal.pone.0281212","article-title":"The impact of visuospatial and executive function on activity performance and outcome after robotic or conventional gait training, long-term after stroke-as part of a randomized controlled trial.","volume":"18","author":"Bergqvist","year":"2023","journal-title":"PLoS One"},{"key":"R31-20250206","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.2522\/ptj.20140492","article-title":"Motor and visuospatial attention and motor planning after stroke: considerations for the rehabilitation of standing balance and gait.","volume":"95","author":"Peters","year":"2015","journal-title":"Phys Ther"},{"key":"R32-20250206","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12877-021-02055-7","article-title":"Associations between post-stroke motor and cognitive function: a cross-sectional study.","volume":"21","author":"Einstad","year":"2021","journal-title":"BMC Geriatr"},{"key":"R33-20250206","doi-asserted-by":"crossref","first-page":"e0153469","DOI":"10.1371\/journal.pone.0153469","article-title":"The role of cognitive factors in predicting balance and fall risk in a neuro-rehabilitation setting.","volume":"11","author":"Saverino","year":"2016","journal-title":"PLoS One"},{"key":"R34-20250206","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.physio.2015.03.3719","article-title":"Executive dysfunction and balance function post-stroke: a cross-sectional study.","volume":"102","author":"Hayes","year":"2016","journal-title":"Physiotherapy"},{"key":"R35-20250206","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.3109\/09638288.2011.553703","article-title":"Cognitive function and improvement of balance after stroke in elderly people: the Gothenburg cognitive stroke study in the elderly.","volume":"33","author":"P\u00e5hlman","year":"2011","journal-title":"Disabil Rehabil"},{"key":"R36-20250206","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jocn.2021.08.009","article-title":"Effects of cognitive motor dual-task training on stroke patients: a RCT-based meta-analysis.","volume":"92","author":"Zhou","year":"2021","journal-title":"J Clin Neurosci"},{"key":"R37-20250206","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1159\/000097642","article-title":"Executive function is independently associated with performances of balance and mobility in community-dwelling older adults after mild stroke: implications for falls prevention.","volume":"23","author":"Liu-Ambrose","year":"2007","journal-title":"Cerebrovasc Dis"},{"key":"R38-20250206","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s40141-020-00283-3","article-title":"Post-stroke cognitive impairments and responsiveness to motor rehabilitation: a review.","volume":"8","author":"VanGilder","year":"2020","journal-title":"Curr Phys Med Rehabil Rep"},{"key":"R39-20250206","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1177\/0269215518758482","article-title":"Dual-task training effects on motor and cognitive functional abilities in individuals with stroke: a systematic review.","volume":"32","author":"He","year":"2018","journal-title":"Clin Rehabil"},{"key":"R40-20250206","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jns.2018.04.012","article-title":"The clinical utility of a 30-minute neuropsychological assessment battery in inpatient stroke rehabilitation.","volume":"390","author":"Jaywant","year":"2018","journal-title":"J Neurol Sci"},{"key":"R41-20250206","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1080\/09602011.2020.1810710","article-title":"Feasibility and acceptability of the multicontext approach for individuals with acquired brain injury in acute inpatient rehabilitation: a single case series.","volume":"32","author":"Jaywant","year":"2022","journal-title":"Neuropsychol Rehabil"}],"container-title":["International Journal of Rehabilitation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MRR.0000000000000648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T18:01:55Z","timestamp":1738864915000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/MRR.0000000000000648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,24]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1097\/mrr.0000000000000648","relation":{},"ISSN":["0342-5282","1473-5660"],"issn-type":[{"value":"0342-5282","type":"print"},{"value":"1473-5660","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,24]]}}}