{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:50:16Z","timestamp":1791039016357,"version":"4.1.0"},"reference-count":55,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuropathology and Experimental Neurology"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1097\/nen.0b013e3180517477","type":"journal-article","created":{"date-parts":[[2008,5,4]],"date-time":"2008-05-04T11:27:45Z","timestamp":1209900465000},"page":"363-371","source":"Crossref","is-referenced-by-count":75,"title":["Effects of the Adenosine A2A Receptor Antagonist SCH 58621 on Cyclooxygenase-2 Expression, Glial Activation, and Brain-Derived Neurotrophic Factor Availability in a Rat Model of Striatal Neurodegeneration"],"prefix":"10.1093","volume":"66","author":[{"given":"Luisa","family":"Minghetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Luisa","family":"Potenza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Pezzola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Blum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadiombo","family":"Bantubungi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Popoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"R1-5-20131205","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0031-6997(24)01511-4","volume":"53","author":"Fredholm","year":"2001","journal-title":"Pharmacol Rev"},{"key":"R2-5-20131205","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/cne.903040206","volume":"304","author":"Schiffmann","year":"1991","journal-title":"J Comp Neurol"},{"key":"R3-5-20131205","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1517\/14728222.4.5.635","volume":"4","author":"Impagnatiello","year":"2000","journal-title":"Emerg Ther Targets"},{"key":"R4-5-20131205","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0166-2236(97)01096-5","volume":"20","author":"Ferre","year":"1997","journal-title":"Trends Neurosci"},{"key":"R5-5-20131205","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1615\/CritRevNeurobiol.v16.i12.110","volume":"16","author":"Popoli","year":"2004","journal-title":"Crit Rev Neurobiol"},{"key":"R6-5-20131205","doi-asserted-by":"crossref","first-page":"5361","DOI":"10.1523\/JNEUROSCI.23-12-05361.2003","volume":"23","author":"Blum","year":"2003","journal-title":"J Neurosci"},{"key":"R7-5-20131205","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/BF03033210","volume":"3","author":"Morelli","year":"2001","journal-title":"Neurotoxicity Res"},{"key":"R8-5-20131205","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1046\/j.1471-4159.2003.02145.x","volume":"88","author":"Fink","year":"2004","journal-title":"J Neurochem"},{"key":"R9-5-20131205","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S1474-4422(03)00411-3","volume":"2","author":"Blum","year":"2003","journal-title":"Lancet Neurol"},{"key":"R10-5-20131205","first-page":"1","volume":"21","author":"Chen","year":"2001","journal-title":"J Neurosci"},{"key":"R11-5-20131205","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1046\/j.0022-3042.2001.00694.x","volume":"80","author":"Ikeda","year":"2002","journal-title":"J Neurochem"},{"key":"R12-5-20131205","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1523\/JNEUROSCI.22-05-01967.2002","volume":"22","author":"Popoli","year":"2002","journal-title":"J Neurosci"},{"key":"R13-5-20131205","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1006\/exnr.2000.7350","volume":"162","author":"Kanda","year":"2000","journal-title":"Exp Neurol"},{"key":"R14-5-20131205","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s100720170052","volume":"22","author":"Morelli","year":"2001","journal-title":"Neurol Sci"},{"key":"R15-5-20131205","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1523\/JNEUROSCI.11-06-01649.1991","volume":"11","author":"Beal","year":"1991","journal-title":"J Neurosci"},{"key":"R16-5-20131205","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0361-9230(94)90109-0","volume":"35","author":"Popoli","year":"1994","journal-title":"Brain Res Bull"},{"key":"R17-5-20131205","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/(SICI)1098-1136(199610)18:2<152::AID-GLIA7>3.0.CO;2-2","volume":"18","author":"Fiebich","year":"1996","journal-title":"Glia"},{"key":"R18-5-20131205","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/j.1471-4159.2005.03395.x","volume":"95","author":"Saura","year":"2005","journal-title":"J Neurochem"},{"key":"R19-5-20131205","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1046\/j.1460-9568.2003.02907.x","volume":"18","author":"Lee","year":"2003","journal-title":"Eur J Neurosci"},{"key":"R20-5-20131205","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/S0024-3205(00)01036-5","volume":"68","author":"Li","year":"2001","journal-title":"Life Sci"},{"key":"R21-5-20131205","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1124\/jpet.103.049700","volume":"306","author":"Salzberg-Brenhouse","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"R22-5-20131205","first-page":"129","volume":"2","author":"Martire","year":"2006","journal-title":"Purinergic Signaling"},{"key":"R23-5-20131205","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1046\/j.1460-9568.2003.02844.x","volume":"18","author":"Fusco","year":"2003","journal-title":"Eur J Neurosci"},{"key":"R24-5-20131205","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1097\/00001756-199812010-00034","volume":"9","author":"Monopoli","year":"1998","journal-title":"Neuroreport"},{"key":"R25-5-20131205","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0006-8993(02)03753-8","volume":"959","author":"Melani","year":"2003","journal-title":"Brain Res"},{"key":"R26-5-20131205","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1097\/00005072-199911000-00008","volume":"58","author":"Minghetti","year":"1999","journal-title":"J Neuropathol Exp Neurol"},{"key":"R27-5-20131205","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1460-9568.2005.04539.x","volume":"23","author":"Battista","year":"2006","journal-title":"Eur J Neurosci"},{"key":"R28-5-20131205","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1093\/jnen\/59.10.866","volume":"59","author":"Minghetti","year":"2000","journal-title":"J Neuropathol Exp Neurol"},{"key":"R29-5-20131205","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.nbd.2004.09.017","volume":"18","author":"Bantubungi","year":"2005","journal-title":"Neurobiol Dis"},{"key":"R30-5-20131205","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2174\/1567202043362036","volume":"1","author":"Greco","year":"2004","journal-title":"Curr Neurovascular Res"},{"key":"R31-5-20131205","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0006-8993(98)00708-2","volume":"804","author":"Hashimoto","year":"1998","journal-title":"Brain Res"},{"key":"R32-5-20131205","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1046\/j.1460-9568.2003.02643.x","volume":"17","author":"Shaw","year":"2003","journal-title":"Eur J Neurosci"},{"key":"R33-5-20131205","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/jnen\/63.9.901","volume":"63","author":"Minghetti","year":"2004","journal-title":"J Neuropathol Exp Neurol"},{"key":"R34-5-20131205","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1126\/science.294.5548.1871","volume":"294","author":"Funk","year":"2001","journal-title":"Science"},{"key":"R35-5-20131205","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1002\/ana.20078","volume":"55","author":"Manabe","year":"2004","journal-title":"Ann Neurol"},{"key":"R36-5-20131205","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/sj.jcbfm.9600369","volume":"27","author":"Kunz","year":"2007","journal-title":"J Cereb Flow Metab"},{"key":"R37-5-20131205","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1111\/j.1471-4159.2004.02577.x","volume":"90","author":"Jiang","year":"2004","journal-title":"J Neurochem"},{"key":"R38-5-20131205","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1111\/j.1471-4159.2005.03150.x","volume":"93","author":"Pepicelli","year":"2005","journal-title":"J Neurochem"},{"key":"R39-5-20131205","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1523\/JNEUROSCI.17-08-02746.1997","volume":"17","author":"Nogawa","year":"1997","journal-title":"J Neurosci"},{"key":"R40-5-20131205","doi-asserted-by":"crossref","first-page":"10954","DOI":"10.1073\/pnas.95.18.10954","volume":"95","author":"Nakayama","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"R41-5-20131205","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1161\/01.STR.30.9.1900","volume":"30","author":"Koistinaho","year":"1999","journal-title":"Stroke"},{"key":"R42-5-20131205","first-page":"309","volume":"45","author":"Stone","year":"1993","journal-title":"Pharmacol Rev"},{"key":"R43-5-20131205","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0165-6147(90)90184-A","volume":"11","author":"Meldrum","year":"1990","journal-title":"Trends Pharmacol Sci"},{"key":"R44-5-20131205","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/(SICI)1098-1063(1999)9:5<527::AID-HIPO6>3.0.CO;2-U","volume":"9","author":"Robledo","year":"1999","journal-title":"Hippocampus"},{"key":"R46-5-20131205","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/glia.10151","volume":"40","author":"Koistinaho","year":"2002","journal-title":"Glia"},{"key":"R47-5-20131205","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1006\/exnr.2000.7542","volume":"167","author":"Orlando","year":"2001","journal-title":"Exp Neurol"},{"key":"R48-5-20131205","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/39885","volume":"389","author":"Altar","year":"1997","journal-title":"Nature"},{"key":"R49-5-20131205","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1126\/science.1059581","volume":"293","author":"Zuccato","year":"2001","journal-title":"Science"},{"key":"R50-5-20131205","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1046\/j.1471-4159.2003.02041.x","volume":"87","author":"Rite","year":"2003","journal-title":"J Neurochem"},{"key":"R51-5-20131205","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1523\/JNEUROSCI.4485-03.2004","volume":"24","author":"McCullough","year":"2004","journal-title":"J Neurosci"},{"key":"R52-5-20131205","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.nbd.2006.01.010","volume":"23","author":"Ajmone-Cat","year":"2006","journal-title":"Neurobiol Dis"},{"key":"R53-5-20131205","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1523\/JNEUROSCI.19-05-01708.1999","volume":"19","author":"Batchelor","year":"1999","journal-title":"J Neurosci"},{"key":"R54-5-20131205","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0306-4522(02)00232-4","volume":"113","author":"Venero","year":"2002","journal-title":"Neuroscience"},{"key":"R55-5-20131205","doi-asserted-by":"crossref","first-page":"9250","DOI":"10.1523\/JNEUROSCI.1856-06.2006","volume":"26","author":"Mojsilovic-Petrovic","year":"2006","journal-title":"J Neurosci"},{"key":"R56-5-20131205","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.it.2003.11.003","volume":"25","author":"Hasko","year":"2004","journal-title":"Trends Immunol"}],"container-title":["Journal of Neuropathology and Experimental Neurology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T01:46:53Z","timestamp":1738201613000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnen\/article-lookup\/doi\/10.1097\/nen.0b013e3180517477"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":55,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1097\/nen.0b013e3180517477","relation":{},"ISSN":["0022-3069"],"issn-type":[{"value":"0022-3069","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}