{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:02:49Z","timestamp":1792735369685,"version":"4.5.0"},"reference-count":63,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neuropathol Exp Neurol"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1097\/nen.0b013e3181a9360f","type":"journal-article","created":{"date-parts":[[2009,6,25]],"date-time":"2009-06-25T07:23:52Z","timestamp":1245914632000},"page":"736-746","source":"Crossref","is-referenced-by-count":43,"title":["Neurotrophic Factors Improve Motoneuron Survival and Function of Muscle Reinnervated by Embryonic Neurons"],"prefix":"10.1093","volume":"68","author":[{"given":"Robert M.","family":"Grumbles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Sesodia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine K.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,7,1]]},"reference":[{"key":"2015121021583198000_68.7.736.1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2005.22.544"},{"key":"2015121021583198000_68.7.736.2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880140506"},{"key":"2015121021583198000_68.7.736.3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4695(199908)40:2<185::AID-NEU5>3.0.CO;2-#"},{"key":"2015121021583198000_68.7.736.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07603-1"},{"key":"2015121021583198000_68.7.736.5","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199707)20:7<788::AID-MUS2>3.0.CO;2-3"},{"key":"2015121021583198000_68.7.736.6","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20400"},{"key":"2015121021583198000_68.7.736.7","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1991.sp018748"},{"key":"2015121021583198000_68.7.736.8","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.081083"},{"key":"2015121021583198000_68.7.736.9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-7580.1998.19240529.x"},{"key":"2015121021583198000_68.7.736.10","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-001-0504-6"},{"key":"2015121021583198000_68.7.736.11","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199307000-00003"},{"key":"2015121021583198000_68.7.736.12","doi-asserted-by":"publisher","DOI":"10.1007\/BF00687678"},{"key":"2015121021583198000_68.7.736.13","unstructured":"Sunderland S . Nerve and Nerve Injuries . Baltimore, MD: The Williams & Wilkins Company, 1968"},{"key":"2015121021583198000_68.7.736.14","doi-asserted-by":"publisher","DOI":"10.1007\/BF01260889"},{"key":"2015121021583198000_68.7.736.15","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0185(20000301)258:3<305::AID-AR10>3.0.CO;2-A"},{"key":"2015121021583198000_68.7.736.16","unstructured":"Gutmann E Young JZ . The re-innervation of muscle after various periods of atrophy. J Anat 1944;78:15\u201343"},{"key":"2015121021583198000_68.7.736.17","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1969.0091"},{"key":"2015121021583198000_68.7.736.18","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160712"},{"key":"2015121021583198000_68.7.736.19","doi-asserted-by":"crossref","unstructured":"Fu SY Gordon T . Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation. J Neurosci 1995;15:3886\u201389","DOI":"10.1523\/JNEUROSCI.15-05-03886.1995"},{"key":"2015121021583198000_68.7.736.20","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2006.23.479"},{"key":"2015121021583198000_68.7.736.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.trim.2003.12.017"},{"key":"2015121021583198000_68.7.736.22","doi-asserted-by":"crossref","unstructured":"Erb DE Mora RJ Bunge RP . Reinnervation of adult rat gastrocnemius muscle by embryonic motoneurons transplanted into the axotomized tibial nerve. Exp Neurol 1993;124:37\u201376","DOI":"10.1006\/exnr.1993.1208"},{"key":"2015121021583198000_68.7.736.23","doi-asserted-by":"crossref","unstructured":"Thomas CK Erb DE Grumbles RM Bunge RP . Embryonic cord transplants in peripheral nerve restore skeletal muscle function. J Neurophysiol 2000;84:591\u201395","DOI":"10.1152\/jn.2000.84.1.591"},{"key":"2015121021583198000_68.7.736.24","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.09.024"},{"key":"2015121021583198000_68.7.736.25","unstructured":"Altman J Bayer SA . Development of the Human Spinal Cord . New York, NY: Oxford University Press, 2001"},{"key":"2015121021583198000_68.7.736.26","doi-asserted-by":"publisher","DOI":"10.1007\/s004410000217"},{"key":"2015121021583198000_68.7.736.27","doi-asserted-by":"crossref","unstructured":"Arce V Pollock RA Philippe JM . Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1). J Neurosci 1998;18:1440\u201348","DOI":"10.1523\/JNEUROSCI.18-04-01440.1998"},{"key":"2015121021583198000_68.7.736.28","doi-asserted-by":"crossref","unstructured":"Politis MJ Ederle K Spencer PS . Tropism in nerve regeneration in vivo. Attraction of regenerating axons by diffusible factors derived from cells in distal nerve stumps of transected peripheral nerves. Brain Res 1982;253:1\u201312","DOI":"10.1016\/0006-8993(82)90667-9"},{"key":"2015121021583198000_68.7.736.29","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.13.4169"},{"key":"2015121021583198000_68.7.736.30","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.130.1.137"},{"key":"2015121021583198000_68.7.736.31","doi-asserted-by":"publisher","DOI":"10.2741\/1096"},{"key":"2015121021583198000_68.7.736.32","doi-asserted-by":"crossref","unstructured":"Hanson MG Jr Shen S Wiemelt AP . Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro. J Neurosci 1998;18:7361\u201371","DOI":"10.1523\/JNEUROSCI.18-18-07361.1998"},{"key":"2015121021583198000_68.7.736.33","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.490360607"},{"key":"2015121021583198000_68.7.736.34","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.1999.00585.x"},{"key":"2015121021583198000_68.7.736.35","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4886(02)00024-9"},{"key":"2015121021583198000_68.7.736.36","doi-asserted-by":"publisher","DOI":"10.1179\/174313208X281073"},{"key":"2015121021583198000_68.7.736.37","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-3806(97)00116-8"},{"key":"2015121021583198000_68.7.736.38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.19.6126"},{"key":"2015121021583198000_68.7.736.39","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.19.10471"},{"key":"2015121021583198000_68.7.736.40","unstructured":"Howard CU Reed MG . Unbiased Stereology: Three-Dimensional Measurement in Microscopy . Oxford, UK: BIOS Scientific Publishers Limited, 1998"},{"key":"2015121021583198000_68.7.736.41","doi-asserted-by":"crossref","unstructured":"Grumbles RM Wood P Rudinsky M . Muscle reinnervation with delayed or immediate transplant of embryonic ventral spinal cord cells into adult rat peripheral nerve. Cell Transplant 2002;11:241\u201350","DOI":"10.3727\/096020198390003"},{"key":"2015121021583198000_68.7.736.42","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.109.6.3039"},{"key":"2015121021583198000_68.7.736.43","doi-asserted-by":"crossref","unstructured":"Comella JX Sanz-Rodriguez C Aldea M . Skeletal muscle-derived trophic factors prevent motoneurons from entering an active cell death program in vitro. J Neurosci 1994;14:2674\u201386","DOI":"10.1523\/JNEUROSCI.14-05-02674.1994"},{"key":"2015121021583198000_68.7.736.44","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-0186(96)00148-9"},{"key":"2015121021583198000_68.7.736.45","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.147.5.1049"},{"key":"2015121021583198000_68.7.736.46","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2004.03.001"},{"key":"2015121021583198000_68.7.736.47","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4464-03.2004"},{"key":"2015121021583198000_68.7.736.48","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2006.11.005"},{"key":"2015121021583198000_68.7.736.49","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B10.16700"},{"key":"2015121021583198000_68.7.736.50","doi-asserted-by":"crossref","unstructured":"Yamamoto Y Livet J Pollock RA . Hepatocyte growth factor (HGF\/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons. Development 1997;124:2903\u201313","DOI":"10.1242\/dev.124.15.2903"},{"key":"2015121021583198000_68.7.736.51","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(92)90168-D"},{"key":"2015121021583198000_68.7.736.52","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200105250-00022"},{"key":"2015121021583198000_68.7.736.53","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007674113440"},{"key":"2015121021583198000_68.7.736.54","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(98)00242-X"},{"key":"2015121021583198000_68.7.736.55","unstructured":"McComas AJ . Skeletal Muscle. Form and Function . Champaign, IL: Human Kinetics, 1996"},{"key":"2015121021583198000_68.7.736.56","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(83)90290-X"},{"key":"2015121021583198000_68.7.736.57","doi-asserted-by":"publisher","DOI":"10.1126\/science.7973664"},{"key":"2015121021583198000_68.7.736.58","doi-asserted-by":"publisher","DOI":"10.1007\/s004410050690"},{"key":"2015121021583198000_68.7.736.59","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80247-0"},{"key":"2015121021583198000_68.7.736.60","doi-asserted-by":"publisher","DOI":"10.1023\/B:NEUR.0000020634.59639.cf"},{"key":"2015121021583198000_68.7.736.61","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1997.8859"},{"key":"2015121021583198000_68.7.736.62","unstructured":"Mortimer JT . Motor prostheses. In: Brookhart JM Brooks VB Geiger SR Mountcastle VB , eds. Handbook of Physiology . Bethesda, MD: American Physiological Society, 1981:155\u201387"},{"key":"2015121021583198000_68.7.736.63","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.063966"}],"container-title":["Journal of Neuropathology &amp; Experimental Neurology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T20:16:15Z","timestamp":1633637775000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnen\/article-lookup\/doi\/10.1097\/NEN.0b013e3181a9360f"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":63,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2009,7,1]]},"published-print":{"date-parts":[[2009,7]]}},"alternative-id":["10.1097\/NEN.0b013e3181a9360f"],"URL":"https:\/\/doi.org\/10.1097\/nen.0b013e3181a9360f","relation":{},"ISSN":["0022-3069","1554-6578"],"issn-type":[{"value":"0022-3069","type":"print"},{"value":"1554-6578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}