{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:07:09Z","timestamp":1791328029438,"version":"4.3.1"},"reference-count":59,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neuropathol Exp Neurol"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1097\/nen.0b013e3181af7f23","type":"journal-article","created":{"date-parts":[[2009,7,24]],"date-time":"2009-07-24T03:35:09Z","timestamp":1248406509000},"page":"892-901","source":"Crossref","is-referenced-by-count":16,"title":["Loss of Cerebellar Granule Neurons Is Associated With Punctate but Not With Large Focal Deposits of Prion Protein in Creutzfeldt-Jakob Disease"],"prefix":"10.1093","volume":"68","author":[{"given":"Baptiste A.","family":"Faucheux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Privat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Philippe","family":"Brandel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Sazdovitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Laplanche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude-Alain","family":"Maurage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Jacques","family":"Hauw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Ha\u00efk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,8,1]]},"reference":[{"key":"2015121102432761000_68.8.892.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105173442006"},{"key":"2015121102432761000_68.8.892.2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-6-278"},{"key":"2015121102432761000_68.8.892.3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.23.13363"},{"key":"2015121102432761000_68.8.892.4","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-004-6872-2"},{"key":"2015121102432761000_68.8.892.5","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5298.402"},{"key":"2015121102432761000_68.8.892.6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609241104"},{"key":"2015121102432761000_68.8.892.7","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199908)46:2<224::AID-ANA12>3.0.CO;2-W"},{"key":"2015121102432761000_68.8.892.8","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.8.1641"},{"key":"2015121102432761000_68.8.892.9","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl224"},{"key":"2015121102432761000_68.8.892.10","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390613"},{"key":"2015121102432761000_68.8.892.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(98)01362-9"},{"key":"2015121102432761000_68.8.892.12","doi-asserted-by":"crossref","unstructured":"Privat N Laffont-Proust I Faucheux BA . Human prion diseases: From antibody screening to a standardized fast immunodiagnosis using automation. Mod Pathol 2008;21:140\u201349","DOI":"10.1038\/modpathol.3800994"},{"key":"2015121102432761000_68.8.892.13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2003.00544.x"},{"key":"2015121102432761000_68.8.892.14","doi-asserted-by":"crossref","unstructured":"Laplanche JL Delasnerie-Laupretre N Brandel JP . Molecular genetics of prion diseases in France. French Research Group on Epidemiology of human spongiform encephalopathies. Neurology 1994;44:2347\u201351","DOI":"10.1212\/WNL.44.12.2347"},{"key":"2015121102432761000_68.8.892.15","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.088930"},{"key":"2015121102432761000_68.8.892.16","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.28.4.350"},{"key":"2015121102432761000_68.8.892.17","doi-asserted-by":"publisher","DOI":"10.1007\/BF00312583"},{"key":"2015121102432761000_68.8.892.18","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-81553-9_59"},{"key":"2015121102432761000_68.8.892.19","doi-asserted-by":"publisher","DOI":"10.1007\/BF01625735"},{"key":"2015121102432761000_68.8.892.20","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(91)90124-7"},{"key":"2015121102432761000_68.8.892.21","doi-asserted-by":"crossref","unstructured":"Bell JE Ironside JW . Neuropathology of spongiform encephalopathies in humans. Br Med Bull 1993;49:738\u201377","DOI":"10.1093\/oxfordjournals.bmb.a072645"},{"key":"2015121102432761000_68.8.892.22","unstructured":"Schulz-Schaeffer WJ Giese A Windl O . Polymorphism at codon 129 of the prion protein gene determines cerebellar pathology in Creutzfeldt-Jakob disease. Clin Neuropathol 1996;15:353\u201357"},{"key":"2015121102432761000_68.8.892.23","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410200507"},{"key":"2015121102432761000_68.8.892.24","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1973.00490290058006"},{"key":"2015121102432761000_68.8.892.25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.16.5937"},{"key":"2015121102432761000_68.8.892.26","doi-asserted-by":"publisher","DOI":"10.1016\/0736-5748(93)90079-S"},{"key":"2015121102432761000_68.8.892.27","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-004-0879-2"},{"key":"2015121102432761000_68.8.892.28","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-7-114"},{"key":"2015121102432761000_68.8.892.29","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.2.375"},{"key":"2015121102432761000_68.8.892.30","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.18825-0"},{"key":"2015121102432761000_68.8.892.31","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.18800-0"},{"key":"2015121102432761000_68.8.892.32","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.20.6057"},{"key":"2015121102432761000_68.8.892.33","doi-asserted-by":"publisher","DOI":"10.1126\/science.1090187"},{"key":"2015121102432761000_68.8.892.34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402725101"},{"key":"2015121102432761000_68.8.892.35","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.18.9754"},{"key":"2015121102432761000_68.8.892.36","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(01)00236-6"},{"key":"2015121102432761000_68.8.892.37","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63331-7"},{"key":"2015121102432761000_68.8.892.38","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20559"},{"key":"2015121102432761000_68.8.892.39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1995.tb01097.x"},{"key":"2015121102432761000_68.8.892.40","doi-asserted-by":"publisher","DOI":"10.1007\/BF00369445"},{"key":"2015121102432761000_68.8.892.41","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199803000-00006"},{"key":"2015121102432761000_68.8.892.42","doi-asserted-by":"publisher","DOI":"10.1097\/01.jnen.0000183346.19447.55"},{"key":"2015121102432761000_68.8.892.43","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(96)00212-6"},{"key":"2015121102432761000_68.8.892.44","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1997.6424"},{"key":"2015121102432761000_68.8.892.45","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(97)00067-X"},{"key":"2015121102432761000_68.8.892.46","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(01)00042-X"},{"key":"2015121102432761000_68.8.892.47","doi-asserted-by":"crossref","unstructured":"Giese A Brown DR Groschup MH . Role of microglia in neuronal cell death in prion disease. Brain Pathol 1998;8:449\u201357","DOI":"10.1111\/j.1750-3639.1998.tb00167.x"},{"key":"2015121102432761000_68.8.892.48","doi-asserted-by":"publisher","DOI":"10.1038\/380345a0"},{"key":"2015121102432761000_68.8.892.49","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200108080-00059"},{"key":"2015121102432761000_68.8.892.50","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199903170-00012"},{"key":"2015121102432761000_68.8.892.51","doi-asserted-by":"crossref","unstructured":"Chretien F LePavec G Vallat-Decouvelaere AV . Expression of excitatory amino acid transporter-1 (EAAT-1) in brain macrophages and microglia of patients with prion diseases. J Neuropathol Exp Neurol 2004;63:1058\u201371","DOI":"10.1093\/jnen\/63.10.1058"},{"key":"2015121102432761000_68.8.892.52","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.26.010302.081142"},{"key":"2015121102432761000_68.8.892.53","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408612101"},{"key":"2015121102432761000_68.8.892.54","doi-asserted-by":"publisher","DOI":"10.1080\/14734220260418448"},{"key":"2015121102432761000_68.8.892.55","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20093"},{"key":"2015121102432761000_68.8.892.56","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90168-X"},{"key":"2015121102432761000_68.8.892.57","doi-asserted-by":"publisher","DOI":"10.1038\/416507a"},{"key":"2015121102432761000_68.8.892.58","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4474-08.2008"},{"key":"2015121102432761000_68.8.892.59","doi-asserted-by":"publisher","DOI":"10.1038\/nature03989"}],"container-title":["Journal of Neuropathology &amp; Experimental Neurology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T13:19:10Z","timestamp":1558444750000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnen\/article-lookup\/doi\/10.1097\/NEN.0b013e3181af7f23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":59,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2009,8,1]]},"published-print":{"date-parts":[[2009,8]]}},"alternative-id":["10.1097\/NEN.0b013e3181af7f23"],"URL":"https:\/\/doi.org\/10.1097\/nen.0b013e3181af7f23","relation":{},"ISSN":["0022-3069","1554-6578"],"issn-type":[{"value":"0022-3069","type":"print"},{"value":"1554-6578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8]]}}}