{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:42:31Z","timestamp":1790232151848,"version":"4.1.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neuropathol Exp Neurol"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1097\/nen.0b013e3181c6b84d","type":"journal-article","created":{"date-parts":[[2009,12,24]],"date-time":"2009-12-24T08:17:16Z","timestamp":1261642636000},"page":"53-59","source":"Crossref","is-referenced-by-count":57,"title":["Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein I716F Mutation"],"prefix":"10.1093","volume":"69","author":[{"given":"Cristina","family":"Guardia-Laguarta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Pera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Clarim\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Molinuevo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"S\u00e0nchez-Valle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Llad\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireia","family":"Coma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"G\u00f3mez-Isla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Blesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isidre","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Lle\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,1,1]]},"reference":[{"key":"2016030401091892000_69.1.53.1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajgp.12.2.146"},{"key":"2016030401091892000_69.1.53.2","doi-asserted-by":"publisher","DOI":"10.1038\/360672a0"},{"key":"2016030401091892000_69.1.53.3","doi-asserted-by":"publisher","DOI":"10.1038\/ng0892-345"},{"key":"2016030401091892000_69.1.53.4","doi-asserted-by":"publisher","DOI":"10.1126\/science.2111584"},{"key":"2016030401091892000_69.1.53.5","doi-asserted-by":"publisher","DOI":"10.1126\/science.1971458"},{"key":"2016030401091892000_69.1.53.6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.8.1308"},{"key":"2016030401091892000_69.1.53.7","doi-asserted-by":"publisher","DOI":"10.1038\/nn0901-887"},{"key":"2016030401091892000_69.1.53.8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1009"},{"key":"2016030401091892000_69.1.53.9","doi-asserted-by":"publisher","DOI":"10.1021\/bi00159a011"},{"key":"2016030401091892000_69.1.53.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13555-6"},{"key":"2016030401091892000_69.1.53.11","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M300276200"},{"key":"2016030401091892000_69.1.53.12","doi-asserted-by":"publisher","DOI":"10.1038\/353844a0"},{"key":"2016030401091892000_69.1.53.13","doi-asserted-by":"publisher","DOI":"10.1038\/349704a0"},{"key":"2016030401091892000_69.1.53.14","doi-asserted-by":"publisher","DOI":"10.1126\/science.1925564"},{"key":"2016030401091892000_69.1.53.15","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.12.2087"},{"key":"2016030401091892000_69.1.53.16","doi-asserted-by":"publisher","DOI":"10.1126\/science.8191290"},{"key":"2016030401091892000_69.1.53.17","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.16.1665"},{"key":"2016030401091892000_69.1.53.18","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.26.041002.131334"},{"key":"2016030401091892000_69.1.53.19","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kve180"},{"key":"2016030401091892000_69.1.53.20","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C100410200"},{"key":"2016030401091892000_69.1.53.21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C100357200"},{"key":"2016030401091892000_69.1.53.22","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(94)90458-8"},{"key":"2016030401091892000_69.1.53.23","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.6.3053"},{"key":"2016030401091892000_69.1.53.24","unstructured":"Guerreiro RJ Baquero M Blesa R Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP. Neurobiol Aging 2009. In press"},{"key":"2016030401091892000_69.1.53.25","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181927577"},{"key":"2016030401091892000_69.1.53.26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.06126.x"},{"key":"2016030401091892000_69.1.53.27","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.48.32322"},{"key":"2016030401091892000_69.1.53.28","doi-asserted-by":"publisher","DOI":"10.1021\/bi971071m"},{"key":"2016030401091892000_69.1.53.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2009.02.008"},{"key":"2016030401091892000_69.1.53.30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05643.x"},{"key":"2016030401091892000_69.1.53.31","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200009)48:3<376::AID-ANA13>3.0.CO;2-U"},{"key":"2016030401091892000_69.1.53.32","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(94)90666-1"},{"key":"2016030401091892000_69.1.53.33","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(94)90541-X"},{"key":"2016030401091892000_69.1.53.34","doi-asserted-by":"publisher","DOI":"10.1097\/01.jnen.0000225908.90052.07"},{"key":"2016030401091892000_69.1.53.35","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.40.24743"},{"key":"2016030401091892000_69.1.53.36","doi-asserted-by":"publisher","DOI":"10.1038\/35008626"},{"key":"2016030401091892000_69.1.53.37"},{"key":"2016030401091892000_69.1.53.38","doi-asserted-by":"publisher","DOI":"10.1126\/science.2474201"},{"key":"2016030401091892000_69.1.53.39","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1575-04.2005"},{"key":"2016030401091892000_69.1.53.40","doi-asserted-by":"publisher","DOI":"10.1021\/bi049399k"},{"key":"2016030401091892000_69.1.53.41","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C400473200"},{"key":"2016030401091892000_69.1.53.42","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M507993200"},{"key":"2016030401091892000_69.1.53.43","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400897"},{"key":"2016030401091892000_69.1.53.44","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M806092200"}],"container-title":["Journal of Neuropathology &amp; Experimental Neurology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T22:30:45Z","timestamp":1485383445000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnen\/article-lookup\/doi\/10.1097\/NEN.0b013e3181c6b84d"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,1,1]]},"published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1097\/NEN.0b013e3181c6b84d"],"URL":"https:\/\/doi.org\/10.1097\/nen.0b013e3181c6b84d","relation":{},"ISSN":["0022-3069","1554-6578"],"issn-type":[{"value":"0022-3069","type":"print"},{"value":"1554-6578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}