{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T04:47:37Z","timestamp":1781758057676,"version":"3.54.5"},"reference-count":65,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1097\/nmd.0b013e31827ab268","type":"journal-article","created":{"date-parts":[[2012,12,29]],"date-time":"2012-12-29T00:30:07Z","timestamp":1356741007000},"page":"23-29","source":"Crossref","is-referenced-by-count":12,"title":["Trauma Profile in Egyptian Adolescents With First-Episode Schizophrenia"],"prefix":"10.1097","volume":"201","author":[{"given":"Mounir H.","family":"Fawzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim A.","family":"Kira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohab M.","family":"Fawzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanan E.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maggie M.","family":"Fawzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-5-20210208","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1097\/NMD.0b013e31820c751c","article-title":"Prevalence and clinical impact of childhood trauma in patients with severe mental disorders.","volume":"199","author":"Alvarez","year":"2011","journal-title":"J Nerv Ment Dis"},{"key":"R2-5-20210208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuint.2011.04.010","article-title":"BDNF concentrations are decreased in serum and parietal cortex in immunotoxin 192 IgG-Saporin rat model of cholinergic degeneration.","volume":"59","author":"Angelucci","year":"2011","journal-title":"Neurochem Int"},{"key":"R3-5-20210208","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","article-title":"The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.","volume":"51","author":"Baron","year":"1986","journal-title":"J Pers Soc Psychol"},{"key":"R4-5-20210208","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1192\/bjp.bp.110.083642","article-title":"Childhood sexual abuse and psychosis: Data from a cross-sectional national psychiatric survey in England.","volume":"199","author":"Bebbington","year":"2011","journal-title":"Br J Psychiatry"},{"key":"R5-5-20210208","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/01.nmd.0000243824.84651.6c","article-title":"Psychometric properties of the Early Trauma Inventory-Self Report.","volume":"195","author":"Bremner","year":"2007","journal-title":"J Nerv Ment Dis"},{"key":"R6-5-20210208","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1097\/YCO.0b013e3283436eb7","article-title":"Brain-derived neurotrophic factor: Findings in schizophrenia.","volume":"24","author":"Buckley","year":"2011","journal-title":"Curr Opin Psychiatry"},{"key":"R7-5-20210208","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3109\/15622975.2010.545187","article-title":"Serum brain-derived neurotrophic factor: Determinants and relationship with depressive symptoms in a community population of middle-aged and elderly people.","volume":"13","author":"Bus","year":"2012","journal-title":"World J Biol Psychiatry"},{"key":"R8-5-20210208","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.psychres.2011.01.011","article-title":"Effects of antipsychotics on the serum BDNF levels in schizophrenia.","volume":"189","author":"Chen","year":"2011","journal-title":"Psychiatry Res"},{"key":"R10-5-20210208","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1001\/archgenpsychiatry.2010.147","article-title":"Schizophrenia and other psychotic disorders in a cohort of sexually abused children.","volume":"67","author":"Cutajar","year":"2010","journal-title":"Arch Gen Psychiatry"},{"key":"R11-5-20210208","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.pnpbp.2009.04.018","article-title":"Brain-derived neurotrophic factor plasma levels in patients suffering from post-traumatic stress disorder.","volume":"33","author":"Dellosso","year":"2009","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"R12-5-20210208","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0920-9964(00)00084-0","article-title":"Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses.","volume":"52","author":"Durany","year":"2001","journal-title":"Schizophr Res"},{"key":"R13-5-20210208","first-page":"95","article-title":"Determining simple parameters for social classification for health research.","volume":"8","author":"Fahmy","year":"1983","journal-title":"Bull High Inst Publ Health"},{"key":"R14-5-20210208","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/01.XME.0000403822.37436.43","article-title":"Duration of untreated psychosis in two Arab samples from Egypt and Saudi Arabia: Clinical and sociocultural correlates.","volume":"18","author":"Fawzi","year":"2011","journal-title":"Middle East Curr Psychiatry"},{"key":"R15-5-20210208","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.comppsych.2011.04.064","article-title":"Disordered eating attitudes in Egyptian antipsychotic naive patients with schizophrenia.","volume":"53","author":"Fawzi","year":"2012","journal-title":"Compr Psychiatry"},{"key":"R16-5-20210208","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.psychres.2011.05.010","article-title":"C-reactive protein serum level in drug-free male Egyptian patients with schizophrenia.","volume":"190","author":"Fawzi","year":"2011","journal-title":"Psychiatry Res"},{"key":"R17-5-20210208","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.schres.2007.06.005","article-title":"Tobacco smoking in Egyptian schizophrenia patients with and without obsessive-compulsive symptoms.","volume":"95","author":"Fawzi","year":"2007","journal-title":"Schizophr Res"},{"key":"R19-5-20210208","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1017\/S0033291710000231","article-title":"The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder.","volume":"40","author":"Fisher","year":"2010","journal-title":"Psychol Med"},{"key":"R20-5-20210208","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.schres.2010.12.010","article-title":"Psychotic symptoms in young adults exposed to childhood traumaA 20 year follow-up study.","volume":"127","author":"Galletly","year":"2011","journal-title":"Schizophr Res"},{"key":"R21-5-20210208","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.neulet.2007.04.001","article-title":"Serum levels of brain-derived neurotrophic factor in patients with schizophrenia and bipolar disorder.","volume":"420","author":"Gama","year":"2007","journal-title":"Neurosci Lett"},{"key":"R22-5-20210208","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1176\/appi.ps.54.4.523","article-title":"Traumatic life events and PTSD among women with substance use disorders and schizophrenia.","volume":"54","author":"Gearon","year":"2003","journal-title":"Psychiatr Serv"},{"key":"R23-5-20210208","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/mp.2010.88","article-title":"Brain-derived neurotrophic factor levels in schizophrenia: A systematic review with meta-analysis.","volume":"16","author":"Green","year":"2011","journal-title":"Mol Psychiatry"},{"key":"R24-5-20210208","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jpsychires.2006.01.005","article-title":"Reduced serum BDNF levels in schizophrenic patients on clozapine or typical antipsychotics.","volume":"41","author":"Grillo","year":"2007","journal-title":"J Psychiatr Res"},{"key":"R25-5-20210208","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1093\/schbul\/sbr085","article-title":"Childhood trauma and hippocampal and amygdalar volumes in first-episode psychosis.","volume":"38","author":"Hoy","year":"2012","journal-title":"Schizophr Bull"},{"key":"R26-5-20210208","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.jpsychires.2005.11.004","article-title":"Associations between serum brain-derived neurotrophic factor levels and clinical phenotypes in schizophrenia patients.","volume":"40","author":"Huang","year":"2006","journal-title":"J Psychiatr Res"},{"key":"R27-5-20210208","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.schres.2009.12.035","article-title":"Decreased BDNF in patients with antipsychotic naive first episode schizophrenia.","volume":"119","author":"Jindal","year":"2010","journal-title":"Schizophr Res"},{"key":"R28-5-20210208","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0304-3940(02)00529-3","article-title":"Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets.","volume":"328","author":"Karege","year":"2002","journal-title":"Neurosci Lett"},{"key":"R29-5-20210208","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/j.1399-5618.2007.00478.x","article-title":"Traumatic life events in bipolar disorder: Impact on BDNF levels and psychopathology.","volume":"9","author":"Kauer-SantAnna","year":"2007","journal-title":"Bipolar Disord"},{"key":"R30-5-20210208","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The Positive and Negative Syndrome Scale (PANSS) or schizophrenia.","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"R32-5-20210208","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1600-0447.2005.00623.x","article-title":"Relationships between trauma and psychosis: An exploration of cognitive and dissociative factors.","volume":"112","author":"Kilcommons","year":"2005","journal-title":"Acta Psychiatr Scand"},{"key":"R33-5-20210208","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/jts.20119","article-title":"Sexual and physical abuse among Korean female inpatients with schizophrenia.","volume":"19","author":"Kim","year":"2006","journal-title":"J Trauma Stress"},{"key":"R34-5-20210208","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1177\/1534765608319324","article-title":"Measuring cumulative trauma dose, types, and profiles using a development-based taxonomy of traumas.","volume":"14","author":"Kira","year":"2008","journal-title":"Traumatology"},{"key":"R35-5-20210208","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/15325024.2010.519288","article-title":"Cumulative tertiary appraisals of traumatic events across cultures: Two studies.","volume":"16","author":"Kira","year":"2011","journal-title":"J Loss Trauma"},{"key":"R36-5-20210208","doi-asserted-by":"crossref","first-page":"287","DOI":"10.4103\/0022-3859.41437","article-title":"Childhood trauma and psychosis: Evidence, pathways, and implications.","volume":"54","author":"Larkin","year":"2008","journal-title":"J Postgrad Med"},{"key":"R37-5-20210208","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s10597-009-9248-x","article-title":"Trauma and posttraumatic stress disorder (PTSD) in patients with schizophrenia or schizoaffective disorder.","volume":"45","author":"Lommen","year":"2009","journal-title":"Community Ment Health J"},{"key":"R38-5-20210208","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1097\/01.nmd.0000188970.11916.76","article-title":"Reported history of child sexual abuse in schizophrenia: Associations with heightened symptom levels and poorer participation over four months in vocational rehabilitation.","volume":"193","author":"Lysaker","year":"2005","journal-title":"J Nerv Ment Dis"},{"key":"R39-5-20210208","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4088\/JCP.v58n1205","article-title":"The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: Combined results of the North American trials.","volume":"58","author":"Marder","year":"1997","journal-title":"J Clin Psychiatr"},{"key":"R40-5-20210208","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/oxfordjournals.schbul.a033437","article-title":"Psychopathological syndromes of schizophrenia: Evaluation of the dimensional structure of the positive and negative syndrome scale.","volume":"26","author":"Mass","year":"2000","journal-title":"Schizophr Bull"},{"key":"R41-5-20210208","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.cpr.2011.05.004","article-title":"Voices from the storm: A critical review of quantitative studies of auditory verbal hallucinations and childhood sexual abuse.","volume":"31","author":"McCarthy-Jones","year":"2011","journal-title":"Clin Psychol Rev"},{"key":"R42-5-20210208","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/schbul\/sbl053","article-title":"Environment and schizophrenia: Environmental factors in schizophrenia: Childhood traumaA critical review.","volume":"33","author":"Morgan","year":"2007","journal-title":"Schizophr Bull"},{"key":"R43-5-20210208","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1037\/0022-006X.66.3.493","article-title":"Trauma and posttraumatic stress disorder in severe mental illness.","volume":"66","author":"Mueser","year":"1998","journal-title":"J Consult Clin Psychol"},{"key":"R44-5-20210208","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1097\/NMD.0b013e3181f49bf1","article-title":"Impact of traumatic and violent victimization experiences in individuals with schizophrenia and schizoaffective disorder.","volume":"198","author":"Newman","year":"2010","journal-title":"J Nerv Ment Dis"},{"key":"R45-5-20210208","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s11135-006-9018-6","article-title":"A caution regarding rules of thumb for variance inflation factors.","volume":"41","author":"OBrien","year":"2007","journal-title":"Qual Quantity"},{"key":"R46-5-20210208","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.pnpbp.2008.03.023","article-title":"The effect of early maternal separation on brain derived neurotrophic factor and monoamine levels in adult heterozygous reeler mice.","volume":"32","author":"Ognibene","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"R47-5-20210208","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1192\/bjp.114.513.949","article-title":"Preliminary psychiatric observations in Egypt.","volume":"114","author":"Okasha","year":"1968","journal-title":"Br J Psychiatry"},{"key":"R48-5-20210208","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1001\/archpsyc.62.7.726","article-title":"Assessment of capacity to consent to research among older persons with schizophrenia, Alzheimer disease, or diabetes mellitus: Comparison of a 3-item questionnaire with a comprehensive standardized capacity instrument.","volume":"62","author":"Palmer","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"R49-5-20210208","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/S0028-3908(98)00141-5","article-title":"Transport of brain-derived neurotrophic factor across the blood-brain barrier.","volume":"37","author":"Pan","year":"1998","journal-title":"Neuropharmacology"},{"key":"R50-5-20210208","first-page":"1753","article-title":"Neurotrophins, neuroprotection and the blood-brain barrier.","volume":"3","author":"Pardridge","year":"2002","journal-title":"Curr Opin Investig Drugs"},{"key":"R51-5-20210208","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.euroneuro.2008.12.012","article-title":"Differential effects of aripiprazole and haloperidol on BDNF-mediated signal changes in SH-SY5Y cells.","volume":"19","author":"Park","year":"2009","journal-title":"Eur Neuropsychopharmacol"},{"key":"R52-5-20210208","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.neulet.2011.01.039","article-title":"Serum brain-derived neurotrophic factor and clozapine daily dose in patients with schizophrenia: A positive correlation.","volume":"491","author":"Pedrini","year":"2011","journal-title":"Neurosci Lett"},{"key":"R53-5-20210208","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1017\/S1461145709991015","article-title":"Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: Correlation with plasma BDNF and psychopathology.","volume":"13","author":"Pillai","year":"2010","journal-title":"Int J Neuropsychopharmacol"},{"key":"R54-5-20210208","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.pnpbp.2004.05.008","article-title":"Low serum levels of brain-derived neurotrophic factor in patients with schizophrenia do not elevate after antipsychotic treatment.","volume":"28","author":"Pirildar","year":"2004","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"R55-5-20210208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1348\/14760830260569210","article-title":"Sexual and physical abuse during childhood and adulthood as predictors of hallucinations, delusions and thought disorder.","volume":"76","author":"Read","year":"2003","journal-title":"Psychol Psychother"},{"key":"R56-5-20210208","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1600-0447.2005.00634.x","article-title":"Childhood trauma, psychosis and schizophrenia: A literature review with theoretical and clinical implications.","volume":"112","author":"Read","year":"2005","journal-title":"Acta Psychiatr Scand"},{"key":"R57-5-20210208","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.neulet.2008.05.022","article-title":"Increased serum levels of brain-derived neurotrophic factor in chronic institutionalized patients with schizophrenia.","volume":"439","author":"Reis","year":"2008","journal-title":"Neurosci Lett"},{"key":"R58-5-20210208","first-page":"489","article-title":"Childhood abuse and the positive symptoms of schizophrenia.","volume":"45","author":"Ross","year":"1994","journal-title":"Hosp Community Psychiatry"},{"key":"R59-5-20210208","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1097\/01.nmd.0000126701.23121.fa","article-title":"Instruments for the assessment of childhood trauma in adults.","volume":"192","author":"Roy","year":"2004","journal-title":"J Nerv Ment Dis"},{"key":"R60-5-20210208","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1192\/bjp.bp.106.026708","article-title":"Association between trauma exposure and delusional experiences in a large community-based sample.","volume":"190","author":"Scott","year":"2007","journal-title":"Br J Psychiatry"},{"key":"R61-5-20210208","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1176\/ajp.2007.164.1.166","article-title":"Trauma and psychosis: An analysis of the National Comorbidity Survey.","volume":"164","author":"Shevlin","year":"2007","journal-title":"Am J Psychiatry"},{"key":"R62-5-20210208","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.neulet.2003.08.004","article-title":"Serum brain-derived neurotrophic factor (BDNF) levels in schizophrenia are indistinguishable from controls.","volume":"351","author":"Shimizu","year":"2003","journal-title":"Neurosci Lett"},{"key":"R64-5-20210208","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1192\/bjp.184.5.416","article-title":"Impact of child sexual abuse on mental health: Prospective study in males and females.","volume":"184","author":"Spataro","year":"2004","journal-title":"Br J Psychiatry"},{"key":"R65-5-20210208","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0920-9964(01)00187-6","article-title":"Smoking in schizophreniaAll is not biological.","volume":"56","author":"Srinivasan","year":"2002","journal-title":"Schizophr Res"},{"key":"R66-5-20210208","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neulet.2005.02.054","article-title":"Decreased BDNF in serum of patients with chronic schizophrenia on long-term treatment with antipsychotics.","volume":"382","author":"Tan","year":"2005","journal-title":"Neurosci Lett"},{"key":"R67-5-20210208","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/00001504-200503000-00006","article-title":"The schizophrenia environment.","volume":"18","author":"van Os","year":"2005","journal-title":"Curr Opin Psychiatry"},{"key":"R68-5-20210208","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1093\/schbul\/sbn101","article-title":"Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction.","volume":"34","author":"van Winkel","year":"2008","journal-title":"Schizophr Bull"},{"key":"R70-5-20210208","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.pnpbp.2007.03.010","article-title":"Treatment with risperidone for 4 weeks increased plasma 3-methoxy-4-hydroxypnenylglycol (MHPG) levels, but did not alter plasma brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients.","volume":"31","author":"Yoshimura","year":"2007","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"}],"container-title":["Journal of Nervous & Mental Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/NMD.0b013e31827ab268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T04:29:54Z","timestamp":1620966594000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00005053-201301000-00005"}},"subtitle":["Relation to Psychopathology and Plasma Brain-Derived Neurotrophic Factor"],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":65,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/nmd.0b013e31827ab268","relation":{},"ISSN":["0022-3018"],"issn-type":[{"value":"0022-3018","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}