{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:32:38Z","timestamp":1786120358943,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Spinal subdural hematomas (SSDHs) are rare. Causes are (1) posttraumatic, (2) iatrogenic (following surgery or lumbar puncture), (3) spontaneous including underlying malformations or coagulation deficits. With a systematic review of literature we want to shed light on the last group: symptomatology, etiology, treatment and outcome will we discussed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Systematic review of literature on PubMed for cases of acute nontraumatic noniatrogenic SSDHs in adults (\u226518 y of age). A total of 122 cases were reviewed including 2 cases from our hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There was a slight preponderance of female patients with spontaneous SSDHs and the mean age was 60 years. Spontaneous SSDHs were mostly located in the thoracic region (40%). Motor symptoms were most frequent (89%), followed by pain. Sensory deficits were present in 64%, of which 81% had a sensory level. In 6% radiculating pain, without any focal neurological deficits, was the presenting symptom. SSDHs were mainly caused by a coagulopathy (48%), predominantly due to the use of coumarins (34%). Other causes were underlying (vascular) malformations and vasculitis. Forty-three percent the SSDHs was idiopathic. 72% of patients underwent a decompressive laminectomy. 59% had a favorable outcome and 34% had a poor outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Spontaneous SSDHs were predominantly located in the thoracic spine, presenting with paraparesis\/paraplegia, sensory level and pain. Over 40% was caused by a coagulation defect, most frequently due to coumarins. Six percent of patients presented with radiculating pain without any focal neurological deficits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/nrl.0000000000000100","type":"journal-article","created":{"date-parts":[[2016,12,24]],"date-time":"2016-12-24T20:36:15Z","timestamp":1482611775000},"page":"34-39","source":"Crossref","is-referenced-by-count":49,"title":["Spontaneous Spinal Subdural Hematoma"],"prefix":"10.1097","volume":"22","author":[{"given":"Marlijn H.","family":"de Beer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein M.","family":"Eysink Smeets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hille","family":"Koppen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20230929","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0140-6736(48)91427-5","article-title":"Surgery in haemophilia; a case of spinal subdural haematoma producing paraplegia","volume":"2","author":"Schiller","year":"1948","journal-title":"Lancet"},{"key":"R2-20230929","first-page":"65","article-title":"Nontraumatic acute spinal subdural hematoma: report of five cases and review of the literature","volume":"91","author":"Domenicucci","year":"1999","journal-title":"J Neurosurg"},{"key":"R3-20230929","doi-asserted-by":"crossref","first-page":"E619","DOI":"10.1097\/BRS.0b013e318154c618","article-title":"Acute spontaneous spinal subdural hematoma presenting as paraplegia: a rare cause","volume":"32","author":"Kyriakides","year":"2007","journal-title":"Spine (Phila Pa 1976)"},{"key":"R4-20230929","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1007\/s00701-010-0758-7","article-title":"Spontaneous acute spinal subdural hematoma: spontaneous recovery from severe paraparesis\u2014case report and review","volume":"152","author":"Payer","year":"2010","journal-title":"Acta Neurochir (Wien)"}],"container-title":["The Neurologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00127893-201701000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:26:08Z","timestamp":1786047968000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00127893-201701000-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1097\/nrl.0000000000000100","relation":{},"ISSN":["1074-7931"],"issn-type":[{"value":"1074-7931","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}