{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T11:50:14Z","timestamp":1789905014494,"version":"4.0.1"},"reference-count":57,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1097\/ogx.0b013e31821102b4","type":"journal-article","created":{"date-parts":[[2011,3,5]],"date-time":"2011-03-05T12:23:43Z","timestamp":1299327823000},"page":"736-743","source":"Crossref","is-referenced-by-count":73,"title":["Screening, Diagnosis, and Management of Cytomegalovirus Infection in Pregnancy"],"prefix":"10.1097","volume":"65","author":[{"given":"Yoav","family":"Yinon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Farine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark H.","family":"Yudin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20210212","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1001\/jama.1986.03380140074025","article-title":"Primary cytomegalovirus infection in pregnancy. Incidence, transmission to fetus, and clinical outcome.","volume":"256","author":"Stagno","year":"1986","journal-title":"JAMA"},{"key":"R2-18-20210212","first-page":"101","article-title":"Detection of cytomegalovirus in urine of hearing-impaired and mentally retarded children by PCR and cell culture.","volume":"32","author":"Pultoo","year":"2000","journal-title":"J Commun Dis"},{"key":"R3-18-20210212","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00006254-200204000-00024","article-title":"Congenital cytomegalovirus infection: review of the epidemiology and outcome.","volume":"57","author":"Gaytant","year":"2002","journal-title":"Obstet Gynecol Surv"},{"key":"R4-18-20210212","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.reprotox.2005.02.002","article-title":"Fetal effects of primary and secondary cytomegalovirus infection in pregnancy.","volume":"21","author":"Ornoy","year":"2006","journal-title":"Reprod Toxicol"},{"key":"R6-18-20210212","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/00003081-198209000-00014","article-title":"Maternal cytomegalovirus infection and perinatal transmission.","volume":"25","author":"Stagno","year":"1982","journal-title":"Clin Obstet Gynecol"},{"key":"R7-18-20210212","doi-asserted-by":"crossref","first-page":"S745","DOI":"10.1093\/clinids\/12.Supplement_7.S745","article-title":"Congenital and perinatal cytomegalovirus infections,","volume":"12","author":"Alford","year":"1990","journal-title":"Rev Infect Dis"},{"key":"R8-18-20210212","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0301-2115(95)02198-G","article-title":"Congenital cytomegalovirus infection.","volume":"63","author":"Daniel","year":"1995","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R9-18-20210212","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0002-9378(96)70401-5","article-title":"Congenital cytomegalovirus infection: a long-standing problem still seeking a solution.","volume":"174","author":"Hagay","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"R10-18-20210212","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S1701-2163(16)34480-2","article-title":"Cytomegalovirus infection in pregnancy.","volume":"32","author":"Yinon","year":"2010","journal-title":"J Obstet Gynaecol Can"},{"key":"R11-18-20210212","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jcv.2003.09.012","article-title":"Pathogenesis and prenatal diagnosis of human cytomegalovirus infection.","volume":"29","author":"Revello","year":"2004","journal-title":"J Clin Virol"},{"key":"R12-18-20210212","first-page":"394","article-title":"Cytomegalovirus infection in pregnancy.","volume":"17","author":"Raynor","year":"1993","journal-title":"Semin Perinatol"},{"key":"R13-18-20210212","first-page":"909","article-title":"Prenatal diagnosis of fetal cytomegalovirus infection after primary or recurrent maternal infection.","volume":"94","author":"Nigro","year":"1999","journal-title":"Obstet Gynecol"},{"key":"R14-18-20210212","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1542\/pir.23-5-163","article-title":"Cytomegalovirus infection.","volume":"23","author":"Pass","year":"2002","journal-title":"Pediatr Rev"},{"key":"R15-18-20210212","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00006454-199202000-00007","article-title":"Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality.","volume":"11","author":"Boppana","year":"1992","journal-title":"Pediatr Infect Dis J"},{"key":"R16-18-20210212","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1067\/mpd.2000.107110","article-title":"Prenatal indicators of congenital cytomegalovirus infection.","volume":"137","author":"Lazzarotto","year":"2000","journal-title":"J Pediatr"},{"key":"R17-18-20210212","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1086\/341831","article-title":"Diagnosis and outcome of preconceptional and periconceptional primary human cytomegalovirus infections.","volume":"186","author":"Revello","year":"2002","journal-title":"J Infect Dis"},{"key":"R18-18-20210212","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1471-0528.2004.00328.x","article-title":"Pre- and periconceptional primary cytomegalovirus infection: risk of vertical transmission and congenital disease.","volume":"112","author":"Daiminger","year":"2005","journal-title":"BJOG"},{"key":"R19-18-20210212","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jcv.2009.11.009","article-title":"Human cytomegalovirus in utero transmission: Follow-up of 524 maternal seroconversions.","volume":"47","author":"Bodeus","year":"2010","journal-title":"J Clin Virol"},{"key":"R20-18-20210212","first-page":"881","article-title":"Prenatal diagnosis of congenital cytomegalovirus infection: prospective study of 237 pregnancies at risk.","volume":"95","author":"Liesnard","year":"2000","journal-title":"Obstet Gynecol"},{"key":"R21-18-20210212","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jcv.2005.09.015","article-title":"Congenital cytomegalovirus infection following first trimester maternal infection: symptoms at birth and outcome.","volume":"35","author":"Pass","year":"2006","journal-title":"J Clin Virol"},{"key":"R22-18-20210212","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1471-0528.2007.01651.x","article-title":"Congenital cytomegalovirus infection following primary maternal infection in the third trimester.","volume":"115","author":"Gindes","year":"2008","journal-title":"BJOG"},{"key":"R23-18-20210212","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1001\/jama.289.8.1008","article-title":"Maternal immunity and prevention of congenital cytomegalovirus infection.","volume":"289","author":"Fowler","year":"2003","journal-title":"JAMA"},{"key":"R24-18-20210212","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajog.2009.11.018","article-title":"Human cytomegalovirus reinfection is associated with intrauterine transmission in a highly cytomegalovirus-immune maternal population.","volume":"202","author":"Yamamoto","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"R25-18-20210212","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1128\/CMR.15.4.680-715.2002","article-title":"Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant.","volume":"15","author":"Revello","year":"2002","journal-title":"Clin Microbiol Rev"},{"key":"R26-18-20210212","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1542\/peds.104.1.55","article-title":"Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus.","volume":"104","author":"Boppana","year":"1999","journal-title":"Pediatrics"},{"key":"R27-18-20210212","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s00431-002-1115-5","article-title":"Congenital cytomegalovirus infection after recurrent infection: case reports and review of the literature.","volume":"162","author":"Gaytant","year":"2003","journal-title":"Eur J Pediatr"},{"key":"R28-18-20210212","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/infdis\/145.2.647","article-title":"Infection with cytomegalovirus during pregnancy: specific IgM antibodies as a marker of recent primary infection.","volume":"145","author":"Griffiths","year":"1982","journal-title":"J Infect Dis"},{"issue":"suppl 3","key":"R29-18-20210212","doi-asserted-by":"crossref","first-page":"S468","DOI":"10.1093\/clinids\/10.Supplement_3.S468","article-title":"Diagnosis of cytomegalovirus infection.","volume":"10","author":"Drew","year":"1988","journal-title":"Rev Infect Dis"},{"key":"R30-18-20210212","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1086\/513996","article-title":"Value of cytomegalovirus (CMV) IgG avidity index for the diagnosis of primary CMV infection in pregnant women.","volume":"175","author":"Grangeot-Keros","year":"1997","journal-title":"J Infect Dis"},{"key":"R31-18-20210212","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1471-0528.2006.00854.x","article-title":"Prenatal diagnosis and outcome of congenital cytomegalovirus infection in twin pregnancies.","volume":"113","author":"Yinon","year":"2006","journal-title":"BJOG"},{"key":"R32-18-20210212","first-page":"428","article-title":"Outcome of pregnancies with vertical transmission of primary cytomegalovirus infection.","volume":"100","author":"Lipitz","year":"2002","journal-title":"Obstet Gynecol"},{"key":"R34-18-20210212","first-page":"28","article-title":"Fetal cytomegalovirus infection of the brain: the spectrum of sonographic findings.","volume":"24","author":"Malinger","year":"2003","journal-title":"Am J Neuroradiol"},{"key":"R35-18-20210212","first-page":"615","article-title":"Cytomegalovirus fetal infection: prenatal diagnosis.","volume":"78","author":"Hohlfeld","year":"1991","journal-title":"Obstet Gynecol"},{"key":"R36-18-20210212","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/(SICI)1097-0223(199904)19:4<314::AID-PD542>3.0.CO;2-H","article-title":"Prenatal diagnosis of human cytomegalovirus by culture and polymerase chain reaction: 98 pregnancies leading to congenital infection.","volume":"19","author":"Bodeus","year":"1999","journal-title":"Prenat Diagn"},{"key":"R37-18-20210212","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0029-7844(97)00084-7","article-title":"Prenatal diagnosis of fetal primary cytomegalovirus infection.","volume":"89","author":"Lipitz","year":"1997","journal-title":"Obstet Gynecol"},{"key":"R38-18-20210212","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1002\/pd.1970141002","article-title":"Prenatal diagnosis of congenital human cytomegalovirus infection.","volume":"14","author":"Nicolini","year":"1994","journal-title":"Prenat Diagn"},{"key":"R39-18-20210212","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1128\/JCM.19.6.917-919.1984","article-title":"Rapid detection of cytomegalovirus in MRC-5 cells inoculated with urine specimens by using low-speed centrifugation and monoclonal antibody to an early antigen.","volume":"19","author":"Gleaves","year":"1984","journal-title":"J Clin Microbiol"},{"key":"R40-18-20210212","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1159\/000053976","article-title":"New advances in the diagnosis of congenital cytomegalovirus infection.","volume":"42","author":"Lazzarotto","year":"1999","journal-title":"Intervirology"},{"key":"R41-18-20210212","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1128\/JCM.40.5.1767-1772.2002","article-title":"Real-time PCR quantification of human cytomegalovirus DNA in amniotic fluid samples from mothers with primary infection.","volume":"40","author":"Gouarin","year":"2002","journal-title":"J Clin Microbiol"},{"key":"R42-18-20210212","doi-asserted-by":"crossref","first-page":"3350","DOI":"10.1128\/JCM.37.10.3350-3352.1999","article-title":"Quantification of human cytomegalovirus DNA in amniotic fluid of mothers of congenitally infected fetuses.","volume":"37","author":"Revello","year":"1999","journal-title":"J Clin Microbiol"},{"key":"R43-18-20210212","doi-asserted-by":"crossref","first-page":"380.e1","DOI":"10.1016\/j.ajog.2007.09.052","article-title":"Ultrasound prediction of symptomatic congenital cytomegalovirus infection.","volume":"198","author":"Guerra","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"R44-18-20210212","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/pd.2037","article-title":"Comparison between ultrasound and magnetic resonance imaging in assessment of fetal cytomegalovirus infection.","volume":"28","author":"Picone","year":"2008","journal-title":"Prenat Diagn"},{"key":"R45-18-20210212","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1002\/uog.6129","article-title":"Cytomegalovirus-related fetal brain lesions: comparison between targeted ultrasound examination and magnetic resonance imaging.","volume":"32","author":"Benoist","year":"2008","journal-title":"Ultrasound Obstet Gynecol"},{"key":"R46-18-20210212","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1067\/mob.2000.106347","article-title":"Prenatal diagnosis of symptomatic congenital cytomegalovirus infection.","volume":"183","author":"Guerra","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"R47-18-20210212","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/pd.59","article-title":"Prenatal diagnosis of congenital cytomegalovirus infection in 189 pregnancies with known outcome.","volume":"21","author":"Enders","year":"2001","journal-title":"Prenat Diagn"},{"key":"R48-18-20210212","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1386-6532(99)00016-5","article-title":"Diagnostic and prognostic value of human cytomegalovirus load and IgM antibody in blood of congenitally infected newborns.","volume":"14","author":"Revello","year":"1999","journal-title":"J Clin Virol"},{"key":"R49-18-20210212","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1056\/NEJMoa043337","article-title":"Passive immunization during pregnancy for congenital cytomegalovirus infection.","volume":"353","author":"Nigro","year":"2005","journal-title":"N Engl J Med"},{"key":"R50-18-20210212","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0928-0197(93)90034-3","article-title":"Prenatal treatment of congenital human cytomegalovirus infection by fetal intravascular administration of ganciclovir.","volume":"1","author":"Revello","year":"1993","journal-title":"Clin Diagn Virol"},{"key":"R51-18-20210212","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1086\/516445","article-title":"National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study.","volume":"175","author":"Whitley","year":"1997","journal-title":"J Infect Dis"},{"key":"R52-18-20210212","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0022-3476(03)00192-6","article-title":"Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial.","volume":"143","author":"Kimberlin","year":"2003","journal-title":"J Pediatr"},{"key":"R53-18-20210212","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1097\/01.inf.0000069767.43169.2d","article-title":"Treatment of children with congenital cytomegalovirus infection with ganciclovir.","volume":"22","author":"Michaels","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"R54-18-20210212","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1056\/NEJMoa0804749","article-title":"Vaccine prevention of maternal cytomegalovirus infection.","volume":"360","author":"Pass","year":"2009","journal-title":"N Engl J Med"},{"key":"R55-18-20210212","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/00006454-199603000-00013","article-title":"Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors: a randomized controlled trial.","volume":"15","author":"Adler","year":"1996","journal-title":"Pediatr Infect Dis J"},{"key":"R56-18-20210212","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jpeds.2004.05.041","article-title":"Prevention of child-to-mother transmission of cytomegalovirus among pregnant women.","volume":"145","author":"Adler","year":"2004","journal-title":"J Pediatr"},{"key":"R57-18-20210212","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1053\/j.semperi.2007.01.002","article-title":"Recent advances in the prevention and treatment of congenital cytomegalovirus infections.","volume":"31","author":"Adler","year":"2007","journal-title":"Semin Perinatol"},{"key":"R58-18-20210212","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jpeds.2004.11.020","article-title":"Screening for congenital cytomegalovirus infection: a tapestry of controversies.","volume":"146","author":"Demmler","year":"2005","journal-title":"J Pediatr"},{"key":"R59-18-20210212","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jpeds.2004.09.025","article-title":"A serologic strategy for detecting neonates at risk for congenital cytomegalovirus infection.","volume":"146","author":"Naessens","year":"2005","journal-title":"J Pediatr"}],"container-title":["Obstetrical &amp; Gynecological Survey"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00006254-201011000-00018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:46:34Z","timestamp":1786041994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006254-201011000-00018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":57,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/ogx.0b013e31821102b4","relation":{},"ISSN":["0029-7828"],"issn-type":[{"value":"0029-7828","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}