{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T00:22:02Z","timestamp":1699057322947},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T00:00:00Z","timestamp":1596499200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Abstract<\/jats:title>\n            <jats:p>The authors present the case of a patient who developed an <jats:italic toggle=\"yes\">Aspergillosis flavus<\/jats:italic> (<jats:italic toggle=\"yes\">A flavus<\/jats:italic>) superficial cutaneous infection which was identified at the time of cast removal, 2 weeks after immobilization of a closed distal third humerus fracture. Clinical and microbiological findings, as well as the treatment of this patient, are reported. An otherwise healthy 27-year-old male presented to the orthopaedic surgery clinic 2 weeks after a closed distal humerus fracture, which was initially immobilized with a functional removable brace. Upon cast removal, the patient was noted to have significant brown hyperkeratotic patches and plaques, studded with pustules in an annular configuration on his left posterior and lateral arm. Fungal culture later grew <jats:italic toggle=\"yes\">A flavus<\/jats:italic>. The patient was started on both oral and topical antifungals and operative management of the displaced fracture was delayed until skin lesions resolved. Once clinical examination and negative repeat bedside potassium hydroxide were confirmed, open reduction and internal fixation was performed. The fracture healed uneventfully, and the patient did not develop any signs or symptoms of postoperative infection.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/oi9.0000000000000082","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T17:22:48Z","timestamp":1596561768000},"page":"e082","source":"Crossref","is-referenced-by-count":1,"title":["Fracture treatment in the setting of cutaneous aspergillosis: a case report"],"prefix":"10.1097","volume":"3","author":[{"given":"Ting","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Rehabilitation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Christopher","sequence":"additional","affiliation":[{"name":"Department of Dermatology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha M.","family":"Simske","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Rehabilitation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"Saddler","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Keenan","sequence":"additional","affiliation":[{"name":"Department of Dermatology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul S.","family":"Whiting","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Rehabilitation"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2020,9]]},"reference":[{"key":"R1-20231103","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/1751-7915.12367","article-title":"Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species","volume":"10","author":"Paulussen","year":"2017","journal-title":"Microb Biotechnol."},{"key":"R2-20231103","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1128\/JCM.36.11.3115-3121.1998","article-title":"Cutaneous aspergillosis","volume":"36","author":"van Burik","year":"1998","journal-title":"J Clin Microbiol."},{"key":"R3-20231103","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1086\/421950","article-title":"Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 cases","volume":"39","author":"Steinbach","year":"2004","journal-title":"Clin Infect Dis."},{"issue":"(pt 7)","key":"R4-20231103","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1099\/jmm.0.007799-0","article-title":"Cutaneous infection caused by Aspergillus terreus","volume":"58","author":"Ozer","year":"2009","journal-title":"J Med Microbiol."},{"key":"R5-20231103","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1034\/j.1600-0714.2003.00080.x","article-title":"Molecular epidemiology of invasive stomatitis due to Aspergillus flavus in patients with acute leukemia","volume":"32","author":"Myoken","year":"2003","journal-title":"J Oral Pathol Med."},{"issue":"(pt 6)","key":"R6-20231103","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1099\/mic.0.2007\/007641-0","article-title":"Aspergillus flavus: human pathogen, allergen and mycotoxin producer","volume":"153","author":"Hedayati","year":"2007","journal-title":"Microbiology."},{"key":"R7-20231103","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.injury.2012.08.003","article-title":"Humeral shaft fractures: retrospective results of non-operative and operative treatment of 186 patients","volume":"44","author":"Mahabier","year":"2013","journal-title":"Injury."},{"key":"R8-20231103","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1097\/01.ta.0000222719.52619.2c","article-title":"Nonunion after functional brace treatment of diaphyseal humerus fractures","volume":"62","author":"Ring","year":"2007","journal-title":"J Trauma."},{"key":"R9-20231103","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1302\/0301-620X.72B2.2312570","article-title":"Functional bracing for comminuted extra-articular fractures of the distal third of the humerus","volume":"72","author":"Sarmiento","year":"1990","journal-title":"J Bone Joint Surg Br."}],"container-title":["OTA International: The Open Access Journal of Orthopaedic Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/OI9.0000000000000082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T22:00:46Z","timestamp":1699048846000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/OI9.0000000000000082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,4]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1097\/oi9.0000000000000082","relation":{},"ISSN":["2574-2167","2574-2167"],"issn-type":[{"value":"2574-2167","type":"print"},{"value":"2574-2167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,4]]}}}