{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:32:27Z","timestamp":1786120347833,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1097\/olq.0b013e3182401b69","type":"journal-article","created":{"date-parts":[[2011,12,22]],"date-time":"2011-12-22T04:31:11Z","timestamp":1324528271000},"page":"316-323","source":"Crossref","is-referenced-by-count":54,"title":["Emergence and Characterization of Neisseria gonorrhoeae Isolates With Decreased Susceptibilities to Ceftriaxone and Cefixime in Canada"],"prefix":"10.1097","volume":"39","author":[{"given":"Irene","family":"Martin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam","family":"Sawatzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Hoang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Lefebvre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Mina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Gilmour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-14-20210213","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1517\/14656560902731993","article-title":"The use of cephalosporins for gonorrhea: The impending problem of resistance.","volume":"10","author":"Barry","year":"2009","journal-title":"Expert Opin Pharmacother"},{"key":"R4-14-20210213","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s101560170034","article-title":". Emergence of cephem- and aztreonam-high-resistant Neisseria gonorrhoeae that does not produce -lactamase.","volume":"7","author":"Akasaka","year":"2001","journal-title":"J Infect Chemother"},{"key":"R7-14-20210213","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1099\/jmm.0.007641-0","article-title":". Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods.","volume":"58","author":"Tapsall","year":"2009","journal-title":"J Med Microbiol"},{"key":"R9-14-20210213","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3201\/eid1701.100397","article-title":". Ceftriaxone-resistant Neisseria gonorrhoeae, Japan.","volume":"17","author":"Ohnishi","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"R11-14-20210213","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10156-008-0610-7","article-title":". Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone.","volume":"14","author":"Osaka","year":"2008","journal-title":"J Infect Chemother"},{"key":"R12-14-20210213","doi-asserted-by":"crossref","first-page":"3744","DOI":"10.1128\/AAC.00304-09","article-title":". Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.","volume":"53","author":"Zhao","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"R14-14-20210213","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1139\/m79-075","article-title":"Auxanographic grouping and typing of Neisseria gonorrhoeae.","volume":"25","author":"Hendry","year":"1979","journal-title":"Can J Microbiol"},{"key":"R16-14-20210213","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1086\/383047","article-title":". Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area.","volume":"189","author":"Martin","year":"2004","journal-title":"J Infect Dis"},{"key":"R17-14-20210213","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1128\/AAC.49.1.137-143.2005","article-title":". Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in central Japan.","volume":"49","author":"Ito","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"R18-14-20210213","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1128\/AAC.45.9.2651-2654.2001","article-title":". Multidrug-resistant strains of Neisseria gonorrhoeae in Greece.","volume":"45","author":"Mavroidi","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"R19-14-20210213","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1128\/AAC.46.3.769-777.2002","article-title":". Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae.","volume":"46","author":"Ropp","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"R20-14-20210213","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1093\/jac\/dkm544","article-title":". Clusters of circulating Neisseria gonorrhoeae strains and association with antimicrobial resistance in Shanghai.","volume":"61","author":"Liao","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"R21-14-20210213","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1080\/00313020701444515","article-title":". Use of a novel screening PCR indicates presence of Neisseria gonorrhoeae isolates with a mosaic penA gene sequence in Australia.","volume":"39","author":"Whiley","year":"2007","journal-title":"Pathology"},{"key":"R23-14-20210213","first-page":"406","article-title":"The neighbor-joining method: A new method for reconstructing phylogenetic trees.","volume":"4","author":"Saitou","year":"1987","journal-title":"Mol Biol Evol"},{"key":"R25-14-20210213","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":". MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0.","volume":"24","author":"Tamura","year":"2007","journal-title":"Mol Biol Evol"},{"key":"R26-14-20210213","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1093\/jac\/dkq187","article-title":". Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2.","volume":"65","author":"Whiley","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"R27-14-20210213","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1136\/sti.2010.045377","article-title":". Emergence, spread and characteristics of Neisseria gonorrhoeae isolates with in vitro decreased susceptibility and resistance to extended-spectrum cephalosporins in Sweden.","volume":"86","author":"Golparian","year":"2010","journal-title":"Sex Transm Infect"},{"key":"R28-14-20210213","doi-asserted-by":"crossref","first-page":"4032","DOI":"10.1128\/AAC.00406-09","article-title":". Mosaic penicillin-binding protein 2 in Neisseria gonorrhoeae isolates collected in 2008 in San Francisco, California.","volume":"53","author":"Pandori","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"R29-14-20210213","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1128\/AAC.01108-09","article-title":"Characteristics and population dynamics of mosaic penA allele-containing Neisseria gonorrhoeae isolates collected in Sydney, Australia, in 2007-2008.","volume":"54","author":"Tapsall","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"R30-14-20210213","first-page":"2141","article-title":"Cephalosporin MIC creep among gonococci: Time for a pharmacodynamic rethink J Antimicrob C","volume":"65","author":"Chisholm","year":"2010","journal-title":"hemother"}],"container-title":["Sexually Transmitted Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00007435-201204000-00014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:32:41Z","timestamp":1786048361000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00007435-201204000-00014"}},"subtitle":["2001\u20132010"],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/olq.0b013e3182401b69","relation":{},"ISSN":["0148-5717"],"issn-type":[{"value":"0148-5717","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}