{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T22:46:08Z","timestamp":1793659568791,"version":"4.5.1"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare anterior and posterior corneal curvatures between eyes with primary open\u2010angle glaucoma (POAG) and healthy eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a prospective, cross\u2010sectional, observer\u2010masked study. A total of 138 white subjects (one eye per patient) were consecutively recruited; 69 eyes had POAG (study group), and the other 69 comprised a group of healthy control eyes matched for age and central corneal pachymetry with the study ones. Exclusion criteria included any corneal or ocular inflammatory disease, previous ocular surgery, or treatment with carbonic anhydrase inhibitors. The same masked observer performed Goldmann applanation tonometry, ultrasound pachymetry, and Orbscan II topography in all cases. Central corneal thickness, intraocular pressure, and anterior and posterior topographic elevation maps were analyzed and compared between both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients with POAG had greater forward shifting of the posterior corneal surface than that in healthy control eyes (p &lt; 0.01). Significant differences in anterior corneal elevation between controls and POAG eyes were also found (p &lt; 0.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Primary open\u2010angle glaucoma eyes have a higher elevation of the posterior corneal surface than that in central corneal thickness\u2013matched nonglaucomatous eyes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0000000000000019","type":"journal-article","created":{"date-parts":[[2013,8,10]],"date-time":"2013-08-10T09:44:38Z","timestamp":1376127878000},"page":"1098-1103","source":"Crossref","is-referenced-by-count":8,"title":["Orbscan Topography in Primary Open\u2010Angle Glaucoma"],"prefix":"10.1002","volume":"90","author":[{"given":"Esther","family":"Arranz\u2010Marquez","sequence":"first","affiliation":[{"name":"Rey Juan Carlos Hospital M\u00f3stoles, Madrid Spain"},{"name":"Novovision Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gema","family":"Bolivar","sequence":"additional","affiliation":[{"name":"\u201cPr\u00edncipe de Asturias\u201d Universitary Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Pi\u00f1ero","sequence":"additional","affiliation":[{"name":"Department of Optics, Pharmacology and Anatomy University of Alicante Alicante Spain"},{"name":"Foundation for the Visual Quality (FUNCAVIS) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasios G.P.","family":"Konstas","sequence":"additional","affiliation":[{"name":"1st University Department of Ophthalmology AHEPA Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios G.","family":"Mikropoulos","sequence":"additional","affiliation":[{"name":"1st University Department of Ophthalmology AHEPA Hospital Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Teus","sequence":"additional","affiliation":[{"name":"Novovision Madrid Spain"},{"name":"\u201cPr\u00edncipe de Asturias\u201d Universitary Hospital Madrid Spain"},{"name":"University of Alcal\u00e1 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,1]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley HA","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archopht.120.6.701","article-title":"The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open\u2010angle glaucoma","volume":"120","author":"Kass MA","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"e_1_2_7_4_1","first-page":"487","article-title":"Comparison of glaucomatous progression between untreated patients with normal\u2010tension glaucoma and patients with therapeutically reduced intraocular pressures [published erratum appears in Am J Ophthalmol 1999;127(1):120]","volume":"126","author":"Collaborative Normal\u2010Tension Glaucoma Study Group","year":"1998","journal-title":"Am J Ophthalmol"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0002-9394(00)00538-9","article-title":"The Advanced Glaucoma Intervention Study (AGIS): 7. 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