{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T15:40:43Z","timestamp":1774971643804,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>A case of optic nerve hypoplasia (ONH) is reported to demonstrate the value of the Heidelberg Retinal Tomograph II (HRT) in assisting with the diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report.<\/jats:title>\n                    <jats:p>\n                      An 8\u2010year\u2010old black male was referred to our clinic for evaluation of right esotropia and presumed amblyopia. Best\u2010corrected visual acuities were 20\/60\n                      <jats:sup>\u2212<\/jats:sup>\n                      OD (right eye) and 20\/25\n                      <jats:sup>+1<\/jats:sup>\n                      OS (left eye). Cover test showed constant right esotropia, measuring 10\n                      <jats:sup>\u0394<\/jats:sup>\n                      at distance and 16\n                      <jats:sup>\u0394<\/jats:sup>\n                      at near. A smaller optic nerve head was detected OD with absence of the double ring sign. The findings of HRT were consistent with a diagnosis of unilateral ONH, with a disc area of 1.545 mm\n                      <jats:sup>2<\/jats:sup>\n                      OD vs. 2.527 mm\n                      <jats:sup>2<\/jats:sup>\n                      OS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion.<\/jats:title>\n                    <jats:p>The clinical features, management, and associations of ONH are discussed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>HRT is a useful tool to assist in diagnosis of ONH by physically measuring the optic nerve.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e31817c92df","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T14:05:31Z","timestamp":1236261931000},"source":"Crossref","is-referenced-by-count":7,"title":["Value of the Heidelberg Retinal Tomograph in Optic Nerve Hypoplasia"],"prefix":"10.1002","volume":"85","author":[{"given":"Yi","family":"Pang","sequence":"first","affiliation":[{"name":"Illinois College of Optometry Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly A.","family":"Frantz","sequence":"additional","affiliation":[{"name":"Illinois College of Optometry Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7,1]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1038\/sj.eye.6701545","article-title":"Congenital disorders of the optic nerve: excavations and hypoplasia","volume":"18","author":"Dutton GN","year":"2004","journal-title":"Eye"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1177\/08830738060210111701","article-title":"Systemic and ocular findings in 100 patients with optic nerve hypoplasia","volume":"21","author":"Garcia ML","year":"2006","journal-title":"J Child Neurol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S1091-8531(99)70005-4","article-title":"The clinical and morphologic spectrum of optic nerve hypoplasia","volume":"3","author":"Hellstrom A","year":"1999","journal-title":"J AAPOS"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1469-8749.1977.tb08372.x","article-title":"Blindness due to optic\u2010nerve atrophy and hypoplasia in children: an epidemiological study (1944\u20131974)","volume":"19","author":"Jan JE","year":"1977","journal-title":"Dev Med Child Neurol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1136\/bjo.75.9.538","article-title":"Reappraisal of the ratio of disc to macula\/disc diameter in optic nerve hypoplasia","volume":"75","author":"Zeki SM","year":"1991","journal-title":"Br J Ophthalmol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.3928\/0191-3913-19880501-11","article-title":"The disc\u2010macula distance to disc diameter ratio: a new test for confirming optic nerve hypoplasia in young children","volume":"25","author":"Alvarez E","year":"1988","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"e_1_2_6_8_2","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1755-3768.1987.tb07051.x","article-title":"A simple clinical method of assessing patients with optic nerve hypoplasia. 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