{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:33:24Z","timestamp":1777530804038,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100005426","name":"Association for Research in Vision and Ophthalmology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005426","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To investigate the influence of three lubricants of varying viscosity, on postinsertion and 6 h comfort with contact lens wear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Comfort and associated symptoms of dryness were assessed in 15 experienced contact lens wearers. Subjects wore a low Dk lens in one eye and a silicone hydrogel in the other and participated in four separate trials involving no lubricant (baseline), saline, and two commercially available lubricants of differing viscosity. The in\u2010eye lubricants were used immediately following lens insertion and every 2 h postinsertion for a 6 h wear period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Postlens insertion comfort was significantly better for both lens types when lubricants or saline were used compared with no lubricant use. After 6 h lens wear, comfort was influenced by lens type and not by in\u2010eye lubricant or saline use. Also after 6 h lens wear, less dryness sensation was reported for silicone hydrogel lenses when using lubricants but not saline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion.<\/jats:title>\n                    <jats:p>Although lubricant use does help reduce dryness symptoms with silicone hydrogel lens wear, there appears to be minimal longer\u2010term benefit to comfort. Furthermore, increased lubricant viscosity did not lead to improved longer\u2010term comfort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e3181819f37","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T03:07:22Z","timestamp":1217214442000},"page":"773-777","source":"Crossref","is-referenced-by-count":18,"title":["Lubricant Effects on Low Dk and Silicone Hydrogel Lens Comfort"],"prefix":"10.1002","volume":"85","author":[{"given":"Jerome","family":"Ozkan","sequence":"first","affiliation":[{"name":"The Institute for Eye Research Sydney New South Wales Australia"},{"name":"The Vision Cooperative Research Centre Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Papas","sequence":"additional","affiliation":[{"name":"The Institute for Eye Research Sydney New South Wales Australia"},{"name":"The Vision Cooperative Research Centre Sydney New South Wales Australia"},{"name":"School of Optometry and Vision Science University of New South Wales Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,8,1]]},"reference":[{"key":"e_1_2_8_2_2","article-title":"The role of dryness symptoms in discontinuation of wear and unscheduled lens removals in extended wear of silicone hydrogel lenses","volume":"43","author":"Chalmers RL","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_8_3_2","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/00006324-198912000-00006","article-title":"Symptomatology of HEMA contact lens wear","volume":"66","author":"Brennan NA","year":"1989","journal-title":"Optom Vis Sci"},{"key":"e_1_2_8_4_2","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1046\/j.1475-1313.2002.00066.x","article-title":"A multi\u2010centre study of lapsed contact lens wearers","volume":"22","author":"Young G","year":"2002","journal-title":"Ophthalmic Physiol Opt"},{"key":"e_1_2_8_5_2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/mabi.200500153","article-title":"Biocompatibility of nanofilm\u2010encapsulated silicone and silicone\u2010hydrogel contact lenses","volume":"6","author":"Yasuda H","year":"2006","journal-title":"Macromol Biosci"},{"key":"e_1_2_8_6_2","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0008-4182(05)80116-4","article-title":"Effects of a 0.9% sodium chloride ophthalmic solution on the ocular surface of symptomatic contact lens wearers","volume":"40","author":"Barabino S","year":"2005","journal-title":"Can J Ophthalmol"},{"key":"e_1_2_8_7_2","first-page":"178","article-title":"Is there a better \u201ccomfort drop\u201d?","volume":"61","author":"Caffery BE","year":"1990","journal-title":"J Am Optom Assoc"},{"key":"e_1_2_8_8_2","first-page":"114","article-title":"The effect of soft lens lubricants on symptoms and lens dehydration","volume":"17","author":"Efron N","year":"1991","journal-title":"CLAO J"},{"key":"e_1_2_8_9_2","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00140068-200301000-00010","article-title":"Preservative\u2010free ocular hydrating agents in symptomatic contact lens wearers: saline versus PVP solution","volume":"29","author":"Malet F","year":"2003","journal-title":"Eye Contact Lens"},{"key":"e_1_2_8_10_2","first-page":"14","article-title":"Do in\u2010eye lubricants for contact lens wearers really work?","volume":"5","author":"Efron N","year":"1990","journal-title":"Cont Lens Anterior Eye"},{"key":"e_1_2_8_11_2","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1097\/00006324-199006000-00011","article-title":"Soft lens lubricants and prelens tear film stability","volume":"67","author":"Golding TR","year":"1990","journal-title":"Optom Vis Sci"},{"key":"e_1_2_8_12_2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/01.opx.0000204513.76568.57","article-title":"Rewetting drops containing surface active agents improve the clinical performance of silicone hydrogel contact lenses","volume":"83","author":"Subbaraman LN","year":"2006","journal-title":"Optom Vis Sci"},{"key":"e_1_2_8_13_2","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/OPX.0b013e318046551b","article-title":"Solution toxicity in soft contact lens daily wear is associated with corneal inflammation","volume":"84","author":"Carnt N","year":"2007","journal-title":"Optom Vis Sci"},{"key":"e_1_2_8_14_2","first-page":"258","article-title":"Ocular response observed with silicone hydrogel lenses and multi\u2010purpose solution combinations. Poster 6","volume":"77","author":"Andrasko G","year":"2006","journal-title":"Optometry"},{"key":"e_1_2_8_15_2","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00003226-199207000-00003","article-title":"Ocular surface residence times of artificial tear solutions","volume":"11","author":"Snibson GR","year":"1992","journal-title":"Cornea"},{"key":"e_1_2_8_16_2","first-page":"30","article-title":"Dry eye and artificial tear formulations","volume":"13","author":"Holly FJ","year":"1988","journal-title":"Contact Lens Forum"},{"key":"e_1_2_8_17_2","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1016\/S0142-9612(01)00167-3","article-title":"The clinical use of viscoelastic artificial tears and sodium chloride in dry\u2010eye syndrome","volume":"22","author":"Nepp J","year":"2001","journal-title":"Biomaterials"}],"container-title":["Optometry and Vision Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/OPX.0b013e3181819f37","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1097\/OPX.0b013e3181819f37","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/OPX.0b013e3181819f37","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:21:34Z","timestamp":1774938094000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/OPX.0b013e3181819f37"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1097\/OPX.0b013e3181819f37"],"URL":"https:\/\/doi.org\/10.1097\/opx.0b013e3181819f37","archive":["Portico"],"relation":{},"ISSN":["1040-5488","1538-9235"],"issn-type":[{"value":"1040-5488","type":"print"},{"value":"1538-9235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}