{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:06:51Z","timestamp":1790604411839,"version":"4.1.0"},"reference-count":66,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01\u2010EY10597"],"award-info":[{"award-number":["R01\u2010EY10597"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To provide an overview of some of our electroretinographic (ERG) and psychophysical studies of normal development of rod function and their application to retinopathy of prematurity (ROP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>\n                      ERG responses to full\u2010field stimuli were recorded from dark adapted subjects. Rod photoreceptor sensitivity (S\n                      <jats:sub>ROD<\/jats:sub>\n                      ) was calculated by fit of a biochemical model of the activation of phototransduction to the ERG a\u2010wave. Dark adapted psychophysical thresholds for detecting 2\u00b0 spots in parafoveal (10\u00b0 eccentric) and peripheral (30\u00b0 eccentric) retina were measured and the difference between the thresholds, \u0394\n                      <jats:sub>10\u201030<\/jats:sub>\n                      , was examined as a function of age. S\n                      <jats:sub>ROD<\/jats:sub>\n                      and \u0394\n                      <jats:sub>10\u201030<\/jats:sub>\n                      in term born and former preterm subjects were compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>\n                      In term born infants, (1) the normal developmental increase in S\n                      <jats:sub>ROD<\/jats:sub>\n                      changes proportionately with the amount of rod visual pigment, rhodopsin, and (2) rod\u2010mediated function in central retina is immature compared with that in peripheral retina. In subjects born prematurely, deficits in S\n                      <jats:sub>ROD<\/jats:sub>\n                      persist long after active ROP has resolved. Maturation of rod\u2010mediated thresholds in the central retina is prolonged by mild ROP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>Characterization of the development of normal rod and rod\u2010mediated function provides a foundation for understanding ROP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e3181a6a237","type":"journal-article","created":{"date-parts":[[2009,5,25]],"date-time":"2009-05-25T03:27:26Z","timestamp":1243222046000},"source":"Crossref","is-referenced-by-count":19,"title":["Development of Rod Function in Term Born and Former Preterm Subjects"],"prefix":"10.1002","volume":"86","author":[{"given":"Anne B.","family":"Fulton","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Children's Hospital and Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald M.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Children's Hospital and Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Moskowitz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Children's Hospital and Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,6,1]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"191","article-title":"Background adaptation in human infants: Analysis of b\u2010wave responses","volume":"31","author":"Fulton A","year":"1982","journal-title":"Doc Ophthalmol Proc Ser"},{"key":"e_1_2_5_3_2","first-page":"473","volume-title":"Principles and practice of clinical electrophysiology of vision Second Edition","author":"Fulton A","year":"2006"},{"key":"e_1_2_5_4_2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1023\/B:DOOP.0000005332.88367.b8","article-title":"Development of ERG responses: The ISCEV rod, maximal and cone responses in normal subjects","volume":"107","author":"Fulton AB","year":"2003","journal-title":"Doc Ophthalmol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00156435","article-title":"Scotopic stimulus response relations of the b\u2010wave of the electroretinogram","volume":"68","author":"Fulton AB","year":"1988","journal-title":"Doc Ophthalmol"},{"key":"e_1_2_5_6_2","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.3109\/02713689208999544","article-title":"The rod sensitivity of dark adapted human infants","volume":"11","author":"Fulton AB","year":"1992","journal-title":"Curr Eye Res"},{"key":"e_1_2_5_7_2","first-page":"1588","article-title":"The development of scotopic sensitivity","volume":"41","author":"Fulton AB","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_8_2","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/0042-6989(91)90050-F","article-title":"Temporal summation in dark adapted 10\u2010week\u2010old infants","volume":"31","author":"Fulton AB","year":"1991","journal-title":"Vision Res"},{"key":"e_1_2_5_9_2","unstructured":"HansenR FultonA. 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