{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:34:32Z","timestamp":1792733672244,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To report the results of 12\u2010month wear of three novel spectacle lens designs intended to reduce peripheral hyperopic defocus and one standard design control lens and their effect on the progression of myopia in Chinese children aged 6 to 16 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Chinese children (n = 210) with myopia (\u22120.75 D to \u22123.50 D sphere, cylinder \u2264\u22121.50 D) were randomized to one of four groups wearing either one of three novel spectacle lens designs (types I, II, or III) or conventional, single\u2010vision spectacle lenses. Data were collected at 6 and 12 months. Primary and secondary outcome measures were the changes in central cycloplegic auto\u2010refraction and eye axial length, respectively. Peripheral refraction along the horizontal meridian (nasal and temporal) was taken at baseline with and without spectacle lenses. Multivariate linear regression was used to adjust analyses for important covariates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Progression in eyes wearing control spectacle lenses at 6 and 12 months was \u22120.55 D \u00b1 0.35 D and \u22120.78 \u00b1 0.50 D, respectively. For the entire group, no statistically significant differences were observed in the rates of progression with the novel designs in comparison to control spectacle lenses. However, in younger children (6 to 12 years) with parental history of myopia (n = 100), there was significantly less progression (\u22120.68 D \u00b1 0.47 D vs. \u22120.97 D \u00b1 0.48 D) with lens type III compared with control spectacles (mean difference, 0.29 D, std error, 0.11, p = 0.038).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>There were no statistically significant differences in the rate of progression of myopia between the control and novel lens wearing eyes for the age group 6 to 16 years. The finding of reduced progression of myopia with type III lens design in younger children with parental myopia needs to be validated in a more targeted study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e3181ea19c7","type":"journal-article","created":{"date-parts":[[2010,7,9]],"date-time":"2010-07-09T06:46:17Z","timestamp":1278657977000},"page":"631-641","source":"Crossref","is-referenced-by-count":224,"title":["Spectacle Lenses Designed to Reduce Progression of Myopia: 12\u2010Month Results"],"prefix":"10.1002","volume":"87","author":[{"given":"Padmaja","family":"Sankaridurg","sequence":"first","affiliation":[{"name":"Institute for Eye Research Sydney New South Wales Australia"},{"name":"Vision Co\u2010operative Research Centre Sydney New South Wales Australia"},{"name":"School of Optometry and Vision Science University of New South Wales Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Donovan","sequence":"additional","affiliation":[{"name":"Institute for Eye Research Sydney New South Wales Australia"},{"name":"Vision Co\u2010operative Research Centre Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saulius","family":"Varnas","sequence":"additional","affiliation":[{"name":"Carl Zeiss Vision Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Ho","sequence":"additional","affiliation":[{"name":"Institute for Eye Research Sydney New South Wales Australia"},{"name":"Vision Co\u2010operative Research Centre Sydney New South Wales Australia"},{"name":"School of Optometry and Vision Science University of New South Wales Sydney New South Wales 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Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Lin","sequence":"additional","affiliation":[{"name":"International Clinical Trials Center Zhongshan Ophthalmic Centre SunYat Sen University Guangzhou People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Earl L.","family":"Smith","sequence":"additional","affiliation":[{"name":"College of Optometry University of Houston Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Ge","sequence":"additional","affiliation":[{"name":"School of Optometry and Vision Science University of New South Wales Sydney New South Wales Australia"},{"name":"International Clinical Trials Center Zhongshan Ophthalmic Centre SunYat Sen University Guangzhou People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brien","family":"Holden","sequence":"additional","affiliation":[{"name":"Institute for Eye Research 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