{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T23:24:15Z","timestamp":1784849055015,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To determine significant risk factors for any inflammatory and infectious events with soft contact lenses (SCL) in a large retrospective clinical chart review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Charts of patients who presented for SCL care from October 2005 through March 2006 were reviewed and observed for a potential of at least 2 years. Charts from those with office visits involving an event\u2010requiring pharmacologic treatment and\/or interruption of SCL wear were scanned and later adjudicated by a masked panel. Significant factors from a univariate analysis were included in a multivariate analysis for all events and subcategories of events separately. Overnight wear was not consistently recorded and was not analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Charts from 1276 SCL wearers comprised 4120 visits and 1454 years of SCL wear (2908 eye\/yr) and included 306 events of interest in 228 patients. In a multivariate analysis, age &lt;25 years was significantly associated with presenting any event, inflammatory events, and infectious events that may or may not be CL\u2010related [incidence rate ratio (IRR) = 1.3; 95% CI, 1.0 to 1.7; 2.6X, 1.5 to 4.6; and 2.0X, 1.2 to 3.3, respectively]. Ametropia &gt;5.00 D increased risk of any event (IRR = 1.5; 1.2 to 1.9) and for other infectious events (IRR = 1.9; 1.2 to 3.2). Use of daily disposable lenses associated with lid irritation (IRR = 4.5; 2.1 to 9.8) but was not significantly associated with any other type of events. New and hydrogel lens wearers had a lower incidence of all event types (IRR = 0.07; 0.01 to 0.46 and 0.77; 0.59 to 0.99, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>Eighty\u2010two percent of these SCL wearers did not present with any complications during the observation period &gt;2 years. The risk factors for inflammatory and infectious events among SCL wearers in clinical practice are similar to those reported in prospective clinical trials. High ametropia and age &lt;25 years are the risk factors that impact the most types of events.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e3181f31f68","type":"journal-article","created":{"date-parts":[[2010,8,20]],"date-time":"2010-08-20T08:27:43Z","timestamp":1282292863000},"page":"725-735","source":"Crossref","is-referenced-by-count":73,"title":["Risk Factors for Contact Lens Complications in US Clinical Practices"],"prefix":"10.1002","volume":"87","author":[{"given":"Robin L.","family":"Chalmers","sequence":"first","affiliation":[{"name":"Indiana University School of Optometry Bloomington Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Keay","sequence":"additional","affiliation":[{"name":"The George Institute for International Health University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bill","family":"Long","sequence":"additional","affiliation":[{"name":"Independent Project Management Dacula Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Bergenske","sequence":"additional","affiliation":[{"name":"CIBA VISION Corporation Duluth Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Giles","sequence":"additional","affiliation":[{"name":"CIBA VISION Corporation Duluth Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Bullimore","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Optometry Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,10,1]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"34","article-title":"International contact lens prescribing in 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