{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T07:56:25Z","timestamp":1774943785947,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background.<\/jats:title>\n                    <jats:p>Potent antiretroviral therapy can lead to improved immunity in patients with acquired immune deficiency syndrome. However, ocular inflammation can occur in predisposed individuals. This inflammation is referred to as immune\u2010recovery uveitis. Cystoid macular edema (CME) is a complication that can result from this inflammation and is emerging as a major cause of visual loss in human immunodeficiency virus (HIV)\u2010infected patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report.<\/jats:title>\n                    <jats:p>A 52\u2010year\u2010old man presented with complaints of intermittent decreased vision that had coincided with the initiation of antiviral treatment. He also reported metamorphopsia and floaters in both eyes of several years duration. He had a history of HIV for 20 years and was only recently started on Highly Active Antiretroviral Therapy (HAART). He reported a vague history of ocular problems involving his retina. Retinal examination revealed bilateral areas of peripheral scarring from presumed past ocular inflammation and thickening and irregularity at each macula. Ancillary testing was performed, and CME was diagnosed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>Immune\u2010recovery uveitis is a leading cause of visual disturbance in HIV\u2010infected patients with a history of cytomegalovirus (CMV) retinitis on HAART. Although the immune recovery associated with the advent of HAART has decreased the need for potent CMV medications, the heightened immune response can be associated with sight\u2010threatening inflammation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e3182058fd6","type":"journal-article","created":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T03:06:12Z","timestamp":1294369572000},"source":"Crossref","is-referenced-by-count":4,"title":["Cystoid Macular Edema as a Result of Immune\u2010Recovery Uveitis"],"prefix":"10.1002","volume":"88","author":[{"given":"Richard","family":"Guzak","sequence":"first","affiliation":[{"name":"College of Optometry at Nova Southeastern University Davie Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Rodman","sequence":"additional","affiliation":[{"name":"College of Optometry at Nova Southeastern University Davie Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Pizzimenti","sequence":"additional","affiliation":[{"name":"College of Optometry at Nova Southeastern University Davie Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,1]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0002-9394(00)00537-7","article-title":"Immune recovery uveitis","volume":"130","author":"Kuppermann BD","year":"2000","journal-title":"Am J Ophthalmol"},{"key":"e_1_2_4_3_2","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1076\/ocii.7.3.215.4010","article-title":"Immune recovery uveitis","volume":"7","author":"Holland GN","year":"1999","journal-title":"Ocul Immunol Inflamm"},{"key":"e_1_2_4_4_2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1136\/bjo.83.1.47","article-title":"Cystoid macular oedema and cytomegalovirus retinitis in 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