{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:24:28Z","timestamp":1792873468966,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>Albinism is an inherited disorder that affects the melanin biosynthesis pathway, which results in reduced or absent pigment formation. This may lead to increased light transmission through the iris and more reflected light from the fundus. Both these effects contribute to the occurrence of ocular straylight. One aim of this study is to determine whether and how increased iris transmission and fundus reflection in subjects with albinism contributes to the occurrence of ocular straylight. The other aim is to determine the effect that an iris print\u2010contact lens (CL) could have in terms of reducing the occurrence of ocular straylight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Ocular straylight was quantified by means of the straylight parameter s and measured as a function of angle and wavelength in 17 subjects with different types of albinism, none of whom wore an iris print\u2010CL. The measurements were then repeated with the subjects wearing an iris print\u2010CL to reduce the iris transmission component and thus the occurrence of ocular straylight. The contributions of transmission and reflectance components were estimated for each individual.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Straylight level increase varied from normal (s \u22489) to severe (8x). In 15 cases, the reflectance component contributed s &gt;3 to up to s = 17. In eight cases, the transmission component contributed s &gt;3 to up to s = 101. A significant reduction in straylight was observed using an iris print\u2010CL in six subjects with elevated straylight values. In the other 11 subjects with albinism, the iris print\u2010CL had no significant effect on straylight because of the low values of the transmission component.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>This study gives insight into the effects of transmission and reflectance on the total measured straylight occurrence in subjects with albinism. Subjects experiencing increased ocular straylight values may benefit significantly from wearing iris print\u2010CLs because transmission of light through the natural iris may cause a significant increase in straylight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e318212071e","type":"journal-article","created":{"date-parts":[[2011,2,25]],"date-time":"2011-02-25T03:30:23Z","timestamp":1298604623000},"source":"Crossref","is-referenced-by-count":19,"title":["Ocular Straylight in Albinism"],"prefix":"10.1002","volume":"88","author":[{"given":"Bastiaan","family":"Kruijt","sequence":"first","affiliation":[{"name":"Netherlands Institute for Neuroscience Royal Netherlands Academy for Arts and Sciences Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luuk","family":"Franssen","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Neuroscience Royal Netherlands Academy for Arts and Sciences Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liesbeth J. J. M.","family":"Prick","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Academic Medical Center Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes M. J.","family":"van Vliet","sequence":"additional","affiliation":[{"name":"Oculenti Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J. T. P.","family":"van den Berg","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Neuroscience Royal Netherlands Academy for Arts and Sciences Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,1]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/OPX.0b013e3181a5254c","article-title":"Albinism: classification, clinical characteristics, and recent findings","volume":"86","author":"Summers CG","year":"2009","journal-title":"Optom Vis Sci"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/j.ophtha.2006.10.054","article-title":"Correlation of visual acuity with foveal hypoplasia grading by optical coherence tomography in albinism","volume":"114","author":"Seo JH","year":"2007","journal-title":"Ophthalmology"},{"key":"e_1_2_6_4_2","first-page":"1095","article-title":"Vision in albinism","volume":"94","author":"Summers CG","year":"1996","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/0042-6989(91)90057-C","article-title":"Dependence of intraocular straylight on pigmentation and light transmission through the ocular wall","volume":"31","author":"Berg TJ","year":"1991","journal-title":"Vision Res"},{"key":"e_1_2_6_6_2","volume-title":"CIE 146:2002: CIE Equations for Disability Glare","author":"Vos JJ","year":"2002"},{"key":"e_1_2_6_7_2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1475-1313.2009.00638.x","article-title":"Straylight in the human eye: testing objectivity and optical character of the psychophysical measurement","volume":"29","author":"Berg TJ","year":"2009","journal-title":"Ophthalmic Physiol Opt"},{"key":"e_1_2_6_8_2","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1152\/ajplegacy.1911.29.1.76","article-title":"The influence of illumination of the eye on visual acuity","volume":"29","author":"Cobb PW","year":"1911","journal-title":"Am J Physiol"},{"key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/BF00156991","article-title":"Towards a classification of visual impairment","volume":"82","author":"Wildt GJ","year":"1992","journal-title":"Doc Ophthalmol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1167\/iovs.05-0690","article-title":"Compensation comparison method for assessment of retinal straylight","volume":"47","author":"Franssen L","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/0042-6989(90)90096-4","article-title":"The intraocular straylight function in 129 healthy volunteers; dependence on angle, age and pigmentation","volume":"30","author":"Ijspeert JK","year":"1990","journal-title":"Vision Res"},{"key":"e_1_2_6_12_2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/00006324-199502000-00003","article-title":"Analysis of intraocular straylight, especially in relation to age","volume":"72","author":"Berg TJ","year":"1995","journal-title":"Optom Vis Sci"},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.exer.2005.09.007","article-title":"Wavelength dependence of intraocular straylight","volume":"82","author":"Coppens JE","year":"2006","journal-title":"Exp Eye Res"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00164837","article-title":"Functional quantification of diaphany","volume":"75","author":"Berg TJ","year":"1990","journal-title":"Doc Ophthalmol"},{"key":"e_1_2_6_15_2","first-page":"2931","article-title":"Quantitative analysis of iris translucency in Fuchs' heterochromic cyclitis","volume":"34","author":"La Hey E","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1001\/archopht.1949.00900050766005","article-title":"Vision of albinos","volume":"42","author":"Edmunds RT","year":"1949","journal-title":"Arch Ophthal"},{"key":"e_1_2_6_17_2","first-page":"611","article-title":"A light\u2010shielded spectacle for albino patients","volume":"4","author":"Miller D","year":"1972","journal-title":"Ann Ophthalmol"},{"key":"e_1_2_6_18_2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0141-7037(87)80002-2","article-title":"Visual performance with artificial iris contact lenses","volume":"10","author":"Abadi RV","year":"1987","journal-title":"J Br Cont Lens Assoc"},{"key":"e_1_2_6_19_2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1136\/bjo.80.7.617","article-title":"Transillumination of iris and subnormal visual acuity\u2014ocular albinism?","volume":"80","author":"Sj\u00f6dell L","year":"1996","journal-title":"Br J Ophthalmol"},{"key":"e_1_2_6_20_2","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1136\/bjo.48.1.42","article-title":"Transillumination of the iris during routine slit\u2010lamp examination","volume":"48","author":"Abrams JD","year":"1964","journal-title":"Br J Ophthalmol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"crossref","first-page":"34027","DOI":"10.1117\/1.2209555","article-title":"Reliability of the compensation comparison stray\u2010light measurement method","volume":"11","author":"Coppens JE","year":"2006","journal-title":"J Biomed Opt"},{"key":"e_1_2_6_22_2","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.ajo.2007.05.037","article-title":"Straylight effects with aging and lens extraction","volume":"144","author":"Berg TJ","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"e_1_2_6_23_2","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/ICO.0b013e3181c11e29","article-title":"Straylight measurements in contact lens wear","volume":"29","author":"Meulen IJ","year":"2010","journal-title":"Cornea"},{"key":"e_1_2_6_24_2","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1097\/00006324-200111000-00008","article-title":"Effects of contact lens\u2010induced hypoxia on the physiology of the corneal endothelium","volume":"78","author":"Bonanno JA","year":"2001","journal-title":"Optom Vis Sci"},{"key":"e_1_2_6_25_2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/00006324-199108000-00009","article-title":"Factors affecting light scatter in contact lens wearers","volume":"68","author":"Elliott DB","year":"1991","journal-title":"Optom Vis Sci"},{"key":"e_1_2_6_26_2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/00006324-198303000-00003","article-title":"Contrast sensitivity in albinotic patients","volume":"60","author":"Loshin DS","year":"1983","journal-title":"Am J Optom Physiol Opt"},{"key":"e_1_2_6_27_2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3109\/13816819009020976","article-title":"Retinal image quality in albinos. A review","volume":"11","author":"Abadi RV","year":"1990","journal-title":"Ophthalmic Paediatr Genet"}],"container-title":["Optometry and Vision Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/OPX.0b013e318212071e","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1097\/OPX.0b013e318212071e","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/OPX.0b013e318212071e","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:15:02Z","timestamp":1774937702000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/OPX.0b013e318212071e"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1097\/OPX.0b013e318212071e"],"URL":"https:\/\/doi.org\/10.1097\/opx.0b013e318212071e","archive":["Portico"],"relation":{},"ISSN":["1040-5488","1538-9235"],"issn-type":[{"value":"1040-5488","type":"print"},{"value":"1538-9235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}