{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:37:22Z","timestamp":1787726242694,"version":"build-2784847793"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NSF DMS 0811003"],"award-info":[{"award-number":["NSF DMS 0811003"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["R24\u2010EY014792"],"award-info":[{"award-number":["R24\u2010EY014792"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["T32\u2010EY013359"],"award-info":[{"award-number":["T32\u2010EY013359"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["K23EY019097"],"award-info":[{"award-number":["K23EY019097"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To develop a measurement protocol for changes in the shape and size of the ciliary muscle with accommodation using the Zeiss Visante\u2122 anterior segment optical coherence tomography (AS\u2010OCT) and to determine the test\u2010retest repeatability of these measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Subjects were 25 adults aged 23 to 28 years. The ciliary muscle was imaged at two visits with the Visante\u2122 while accommodative response was monitored during imaging using the PowerRefractor. Ciliary muscle thickness (CMT) was measured at 1 mm (CMT1), 2 mm (CMT2), and 3 mm (CMT3) posterior to the scleral spur and at the point of maximal thickness (CMTMAX). Thickness was measured at these locations while subjects viewed a target at distance and at a 4.00 D accommodative stimulus. Outcome measures were the change in thickness between distance and the 4.00 D stimulus and the change in thickness per diopter of accommodative response (PowerRefractor). Finally, the repeatability measurements between visit 1 and visit 2 were determined with a Bland\u2010Altman analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>The statistically significant modeled changes in CMT were as follows: CMTMAX = 69.2 \u03bcm (4.00 D stimulus) and 18.1 \u03bcm (per diopter of accommodation); CMT1 = 45.2 \u03bcm (4.00 D stimulus) and 12.3 \u03bcm (per diopter of accommodation); and CMT3 = \u221245.9 \u03bcm (4.00 D stimulus) and \u221212.0 \u03bcm (per diopter of accommodation); p &lt; 0.0001 for all.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>The combination of the Visante\u2122 and the PowerRefractor is a feasible tool for measuring thickening of ciliary muscle at more anterior locations and thinning at more posterior locations during accommodation. We noted a wide range of accommodative responses during the time of image capture in this study indicating that the most accurate estimates of the change in ciliary muscle dimensions with accommodation may be obtained by using accommodative response rather than stimulus values and by using measurements taken simultaneously with image capture.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e318252cadc","type":"journal-article","created":{"date-parts":[[2012,4,13]],"date-time":"2012-04-13T08:39:49Z","timestamp":1334306389000},"page":"719-726","source":"Crossref","is-referenced-by-count":56,"title":["Measuring Changes in Ciliary Muscle Thickness with Accommodation in Young Adults"],"prefix":"10.1002","volume":"89","author":[{"given":"Laura Ashley","family":"Lossing","sequence":"first","affiliation":[{"name":"College of Optometry The Ohio State University Columbus Ohio"},{"name":"College of Mathematics and Physical Sciences The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loraine T.","family":"Sinnott","sequence":"additional","affiliation":[{"name":"College of Optometry The Ohio State University Columbus Ohio"},{"name":"College of Mathematics and Physical Sciences The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiu\u2010Yen","family":"Kao","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Computer Science Claremont McKenna College Claremont California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Richdale","sequence":"additional","affiliation":[{"name":"SUNY College of Optometry New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa D.","family":"Bailey","sequence":"additional","affiliation":[{"name":"College of Optometry The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,1]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1444-0938.2008.00260.x","article-title":"Restoration of accommodation: surgical options for correction of presbyopia","volume":"91","author":"Glasser A","year":"2008","journal-title":"Clin Exp Optom"},{"key":"e_1_2_11_3_2","first-page":"560","article-title":"General binocular dysfunctions in an urban optometry clinic","volume":"56","author":"Hokoda SC","year":"1985","journal-title":"J Am Optom Assoc"},{"key":"e_1_2_11_4_2","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1097\/00006324-197310000-00008","article-title":"Effectiveness of non\u2010strabismus optometric vision training in a private practice","volume":"50","author":"Hoffman L","year":"1973","journal-title":"Am J Optom Arch Am Acad Optom"},{"key":"e_1_2_11_5_2","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1097\/00006324-197408000-00002","article-title":"The dynamic response of visual accommodation over a seven\u2010day period","volume":"51","author":"Randle RJ","year":"1974","journal-title":"Am J Optom Physiol Opt"},{"key":"e_1_2_11_6_2","first-page":"285","article-title":"Objective assessment of accommodation orthoptics. 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