{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:55:44Z","timestamp":1774954544484,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OVS"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To estimate the prevalence of self\u2010reported \u201csensitive eyes\u201d (SEs) in soft contact lens (CL) wearers, evaluate the clinical characteristics of patients with SEs, and examine the effect of refitting them with silicone hydrogel lenses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>After self\u2010assessment, 2154 CL wearers were separated into SE and non\u2010SE patients. Demographics, biometric data, wearing time, symptoms, and signs were compared between the two populations. Sixty\u2010three SE patients were randomized into senofilcon A (senA) lenses and 65 into a non\u2013senA arm (lotrafilcon B, omafilcon A, and balafilcon A lenses). The performance of senA lenses was compared against habitual and non\u2010senA lenses 2 weeks later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 12.2% of CL wearers reported SEs with their habitual CLs. No significant differences were noticed between SE and non\u2010SE patients in sex, age, or refraction. The prevalence of dryness (43 vs 19%, p &lt; 0.0001), irritation (25 vs 11%, p &lt; 0.0001), redness (20 vs 6%, p &lt; 0.0001), and stinging (6 vs 1%, p &lt; 0.0001) was higher in SE patients. Average wearing time (13.0 vs 14.1 hours, p &lt; 0.0001) was lower in this group. Limbal\/bulbar hyperemia and corneal\/conjunctival staining were not significantly different between the two populations. Senofilcon A increased the number of patients reporting no dryness (habitual vs senA, 20 vs 44%, p &lt; 0.0003), irritation (22 vs 37%, p = 0.015), redness (52 vs 76%, p =0.009) and stinging (58 vs 77%, p = 0.012) but did not significantly affect clinical signs. Senofilcon A was significantly more efficient than non\u2010senA lenses in improving dryness (scale of 0 to 3: senA vs non\u2010senA, 0.64 vs 1.02, p = 0.0056), irritation (0.72 vs 1.16, p = 0.0015), and stinging (0.18 vs 0.53, p = 0.0049).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A substantial proportion of CL wearers report SEs with their habitual lenses. These patients are characterized by a high prevalence of additional symptoms, which are not reflected in clinical signs. Senofilcon A, or lenses with similar properties, may help reduce these symptoms in SE patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/opx.0b013e3182775c78","type":"journal-article","created":{"date-parts":[[2012,11,22]],"date-time":"2012-11-22T02:41:33Z","timestamp":1353552093000},"page":"1682-1690","source":"Crossref","is-referenced-by-count":4,"title":["Eye Sensitivity in Soft Contact Lens Wearers"],"prefix":"10.1002","volume":"89","author":[{"given":"Michael","family":"Spyridon","sequence":"first","affiliation":[{"name":"Visioncare Research Ltd. Farnham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Hickson\u2010Curran","sequence":"additional","affiliation":[{"name":"Vistakon, Johnson &amp; Johnson Vision Care, Inc. Jacksonville Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Hunt","sequence":"additional","affiliation":[{"name":"Visioncare Research Ltd. Farnham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graeme","family":"Young","sequence":"additional","affiliation":[{"name":"Visioncare Research Ltd. Farnham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,1]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.0105-1873.2006.00886.x","article-title":"Sensory, clinical and physiological factors in sensitive skin: a review","volume":"55","author":"Farage MA","year":"2006","journal-title":"Contact Dermatitis"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2334\/josnusd.51.323","article-title":"Diagnosis and treatment of dentinal hypersensitivity","volume":"51","author":"Porto IC","year":"2009","journal-title":"J Oral Sci"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1473-2130.2004.00082.x","article-title":"Sensitive skin: a complex and multifactorial syndrome","volume":"3","author":"Pons\u2010Guiraud A","year":"2004","journal-title":"J Cosmet 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