{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:17:45Z","timestamp":1786119465396,"version":"build-2736575974"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1097\/pai.0b013e3181c1f99f","type":"journal-article","created":{"date-parts":[[2010,4,17]],"date-time":"2010-04-17T04:04:48Z","timestamp":1271477088000},"page":"262-267","source":"Crossref","is-referenced-by-count":7,"title":["Is the Expression Pattern of BD ProExC the Same as Ki-67? A Comparative Analysis in Cervical Biopsies"],"prefix":"10.1097","volume":"18","author":[{"given":"Ann E.","family":"Walts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shikha","family":"Bose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210126","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1083\/jcb.123.3.513","article-title":"The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins","volume":"123","author":"Schluter","year":"1993","journal-title":"J Cell Biol"},{"key":"R2-12-20210126","first-page":"471","article-title":"Immunohistochemical assessment of Ki-67 as prognostic cellular proliferation marker in anal canal carcinoma","volume":"19","author":"Indinnemo","year":"2000","journal-title":"J Exp Clin Cancer Res"},{"key":"R4-12-20210126","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1097\/PAS.0b013e31815bbb69","article-title":"BD ProEx C: a sensitive and specific marker of HPV-associated squamous lesions of the cervix","volume":"32","author":"Badr","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"R5-12-20210126","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/modpathol.2008.101","article-title":"Biomarker (ProEx C, p16 (INK4a), and MiB-1) distinction of high-grade squamous intraepithelial lesion from its mimics","volume":"21","author":"Pinto","year":"2008","journal-title":"Mod Pathol"},{"key":"R6-12-20210126","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/cncr.23496","article-title":"Quantitative detection of molecular markers ProEx C (minichromosome maintenance protein 2 and topoisomerase IIa) and MIB-1 in liquid-based cervical squamous cell cytology","volume":"114","author":"Beccati","year":"2008","journal-title":"Cancer"},{"key":"R7-12-20210126","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/cncr.23951","article-title":"Comparison of ProEx C with p16INK4a and Ki-67 immunohistochemical staining of cell blocks prepared from residual liquid-based cervicovaginal material: a pilot study","volume":"114","author":"Halloush","year":"2008","journal-title":"Cancer"},{"key":"R8-12-20210126","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/cncr.20258","article-title":"The utility of p16INK4a and Ki-67 staining on cell blocks prepared from residual thin-layer cervicovaginal material","volume":"102","author":"Akpolat","year":"2004","journal-title":"Cancer"},{"key":"R9-12-20210126","first-page":"1927","article-title":"Identification of cervical cancer markers by cDNA and tissue microarrays","volume":"63","author":"Chen","year":"2003","journal-title":"Cancer Res"},{"key":"R10-12-20210126","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1586\/14737159.7.2.117","article-title":"Multiple biomarkers in molecular oncology. I. Molecular diagnostics applications in cervical cancer detection","volume":"7","author":"Malinowski","year":"2007","journal-title":"Expert Rev Mol Diagn"},{"key":"R11-12-20210126","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/j.humpath.2007.01.025","article-title":"Evaluation of p16INK4a, minichromosome maintenance protein 2, DNA topoisomerase IIalpha, ProEX C, and p16INK4a\/ProEX C in cervical squamous intraepithelial lesions","volume":"38","author":"Shi","year":"2007","journal-title":"Hum Pathol"},{"key":"R12-12-20210126","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.virol.2004.09.045","article-title":"Gene expression profiles of primary HPV 16- and HPV 18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy","volume":"331","author":"Santin","year":"2005","journal-title":"Virology"},{"key":"R13-12-20210126","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1006\/jsbi.2000.4218","article-title":"The roles of the MCM, ORC and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells","volume":"129","author":"Madine","year":"2000","journal-title":"J Struct Biol"},{"key":"R14-12-20210126","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1006\/excr.1998.4041","article-title":"Stability of the replicative MCM3 protein in proliferating and differentiating human cells","volume":"241","author":"Musahl","year":"1998","journal-title":"Exp Cell Res"},{"key":"R15-12-20210126","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1242\/jcs.114.11.2027","article-title":"DNA replication licensing and human cell proliferation","volume":"114","author":"Stoeber","year":"2001","journal-title":"J Cell Sci"},{"key":"R16-12-20210126","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1038\/sj.bjc.6601234","article-title":"Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions","volume":"89","author":"Chatrath","year":"2003","journal-title":"Br J Cancer"},{"key":"R17-12-20210126","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/sj.bjc.6600729","article-title":"Minichromosome maintenance (MCM) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia","volume":"88","author":"Davidson","year":"2003","journal-title":"Br J Cancer"},{"issue":"2","key":"R18-12-20210126","first-page":"109A","article-title":"ProExC is a marker for HPV-associated anal lesions","volume":"20","author":"Chan","year":"2007","journal-title":"Mod Pathol"},{"key":"R19-12-20210126","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/path.1444","article-title":"A novel immunohistochemical method to estimate cell-cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer","volume":"201","author":"Scott","year":"2003","journal-title":"J Pathol"},{"key":"R20-12-20210126","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1136\/gut.50.3.373","article-title":"Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa","volume":"50","author":"Going","year":"2002","journal-title":"Gut"},{"key":"R21-12-20210126","first-page":"532","article-title":"High expression of minichromosome maintenance protein 6 in classic Hodgkin's lymphoma points to a cell cycle arrest in G1 phase","volume":"11","author":"Karimi","year":"2008","journal-title":"Arch Iran Med"},{"key":"R22-12-20210126","first-page":"245","article-title":"Minichromosome maintenance protein 7 in colorectal cancer: implication of prognostic significance","volume":"33","author":"Nishihara","year":"2008","journal-title":"Int J Oncol"},{"key":"R23-12-20210126","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1080\/02688690120114174","article-title":"Early recurrence of benign meningioma correlates with expression of mini-chromosome maintenance-2 protein","volume":"16","author":"Hunt","year":"2002","journal-title":"Br J Neurosurg"},{"key":"R24-12-20210126","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/sj.bjc.6602795","article-title":"Minichromosome maintenance protein 6, a proliferation marker superior to Ki-67 and independent predictor of survival in patients with mantle cell lymphoma","volume":"93","author":"Schrader","year":"2005","journal-title":"Br J Cancer"},{"key":"R25-12-20210126","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1245\/s10434-006-9188-4","article-title":"Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteria","volume":"13","author":"Huang","year":"2006","journal-title":"Ann Surg Oncol"},{"key":"R26-12-20210126","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1158\/1078-0432.CCR-04-1776","article-title":"Mcm2, Geminin, and KI67 define proliferative state and are prognostic markers in renal cell carcinoma","volume":"11","author":"Dudderidge","year":"2005","journal-title":"Clin Cancer Res"},{"key":"R27-12-20210126","first-page":"2473","article-title":"MCM-2 protein expression predicts prognosis better than Ki-67 antigen in oral cavity squamocellular carcinoma","volume":"26","author":"Szelachowska","year":"2006","journal-title":"Anticancer Res"},{"key":"R28-12-20210126","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0302-2838(02)00580-8","article-title":"Prognostic value of MCM2 immunoreactivity in stage T1 transitional cell carcinoma of the bladder","volume":"43","author":"Kruger","year":"2003","journal-title":"Eur Urol"},{"key":"R31-12-20210126","first-page":"537","article-title":"Comparative toposiomerase IIa and Ki67 protein expression in papillary thyroid carcinoma based on tissue microarrays and image analysis","volume":"13","author":"Manaios","year":"2008","journal-title":"J BUON"},{"key":"R32-12-20210126","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1080\/02841860801995396","article-title":"The value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D","volume":"47","author":"Nielsen","year":"2008","journal-title":"Acta Oncol"},{"key":"R33-12-20210126","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1158\/1078-0432.CCR-07-1494","article-title":"Identification of prognostic biomarkers for prostate cancer","volume":"14","author":"Kosari","year":"2008","journal-title":"Clin Cancer Res"},{"key":"R34-12-20210126","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1002\/ijc.21599","article-title":"Molecular profiling of platinum resistant ovarian cancer","volume":"118","author":"Helleman","year":"2006","journal-title":"Int J Cancer"}],"container-title":["Applied Immunohistochemistry & Molecular Morphology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00129039-201005000-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:19:06Z","timestamp":1786040346000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00129039-201005000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/pai.0b013e3181c1f99f","relation":{},"ISSN":["1541-2016"],"issn-type":[{"value":"1541-2016","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}