{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:07:15Z","timestamp":1786118835359,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1097\/pas.0b013e3180339944","type":"journal-article","created":{"date-parts":[[2007,7,23]],"date-time":"2007-07-23T04:04:06Z","timestamp":1185163446000},"page":"1209-1214","source":"Crossref","is-referenced-by-count":56,"title":["Do Sporadic Peutz-Jeghers Polyps Exist? Experience of a Large Teaching Hospital"],"prefix":"10.1097","volume":"31","author":[{"given":"Ashlie L.","family":"Burkart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Sheridan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Lewin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Fenton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilofar J.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Montgomery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20210131","first-page":"74","article-title":"Tumours of the Digestive System","author":"Aaltonen","year":"2000"},{"key":"R2-11-20210131","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/00000478-200104000-00010","article-title":"Hyperplastic polyps of the stomach: associations with histologic patterns of gastritis and gastric atrophy","volume":"25","author":"Abraham","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"R3-11-20210131","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/jmg.2003.010900","article-title":"Genotype-phenotype correlations in Peutz-Jeghers syndrome","volume":"41","author":"Amos","year":"2004","journal-title":"J Med Genet"},{"key":"R4-11-20210131","doi-asserted-by":"crossref","first-page":"896","DOI":"10.7326\/0003-4819-128-11-199806010-00004","article-title":"Increased risk for cancer in patients with the Peutz-Jeghers syndrome","volume":"128","author":"Boardman","year":"1998","journal-title":"Ann Intern Med"},{"key":"R5-11-20210131","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/1098-1004(200007)16:1<23::AID-HUMU5>3.0.CO;2-M","article-title":"Genetic heterogeneity in Peutz-Jeghers syndrome","volume":"16","author":"Boardman","year":"2000","journal-title":"Hum Mutat"},{"key":"R6-11-20210131","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1136\/jcp.54.2.126","article-title":"Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome","volume":"54","author":"Entius","year":"2001","journal-title":"J Clin Pathol"},{"key":"R7-11-20210131","first-page":"231","article-title":"Progression toward malignancy of hamartomas in a patient with Peutz-Jeghers syndrome: case report and literature review","volume":"37","author":"Flageole","year":"1994","journal-title":"Can J Surg"},{"key":"R8-11-20210131","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1056\/NEJM198706113162404","article-title":"Increased risk of cancer in the Peutz-Jeghers syndrome","volume":"316","author":"Giardiello","year":"1987","journal-title":"N Engl J Med"},{"key":"R9-11-20210131","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.cgh.2005.11.005","article-title":"Peutz-Jeghers syndrome and management recommendations","volume":"4","author":"Giardiello","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"R10-11-20210131","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1158\/1078-0432.CCR-06-0083","article-title":"Frequency and spectrum of cancers in the Peutz-Jeghers syndrome","volume":"12","author":"Hearle","year":"2006","journal-title":"Clin Cancer Res"},{"key":"R11-11-20210131","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1136\/jmg.2005.040535","article-title":"STK11 status and intussusception risk in Peutz-Jeghers syndrome","volume":"43","author":"Hearle","year":"2006","journal-title":"J Med Genet"},{"key":"R12-11-20210131","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1136\/jmg.2005.036830","article-title":"Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome","volume":"43","author":"Hearle","year":"2006","journal-title":"J Med Genet"},{"key":"R13-11-20210131","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/ng0197-87","article-title":"Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis","volume":"15","author":"Hemminki","year":"1997","journal-title":"Nat Genet"},{"key":"R14-11-20210131","first-page":"95","article-title":"Solitary Peutz-Jeghers type polyp of the duodenum containing a focus of adenocarcinoma","volume":"28","author":"Ichiyoshi","year":"1996","journal-title":"Ital J Gastroenterol"},{"key":"R15-11-20210131","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1056\/NEJM194912292412601","article-title":"Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance","volume":"241","author":"Jeghers","year":"1949","journal-title":"N Engl J Med"},{"key":"R16-11-20210131","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/ng0198-38","article-title":"Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase","volume":"18","author":"Jenne","year":"1998","journal-title":"Nat Genet"},{"key":"R17-11-20210131","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000077392","article-title":"A solitary Peutz-Jeghers-type hamartomatous polyp in the duodenum. A case report including results of mutation analysis","volume":"69","author":"Kitaoka","year":"2004","journal-title":"Digestion"},{"key":"R18-11-20210131","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/sj.bjc.6601030","article-title":"Further observations on LKB1\/STK11 status and cancer risk in Peutz-Jeghers syndrome","volume":"89","author":"Lim","year":"2003","journal-title":"Br J Cancer"},{"key":"R19-11-20210131","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1007\/BF01311735","article-title":"Adenocarcinoma of the rectum arising in a hamartomatous polyp in a patient with Peutz-Jeghers syndrome","volume":"28","author":"Miller","year":"1983","journal-title":"Dig Dis Sci"},{"key":"R20-11-20210131","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/oxfordjournals.jjco.a023227","article-title":"A solitary Peutz-Jeghers-type hamartomatous polyp of the rectum: report of a case and review of the literature","volume":"26","author":"Nakayama","year":"1996","journal-title":"Jpn J Clin Oncol"},{"key":"R21-11-20210131","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1007\/BF00309096","article-title":"Solitary hamartomatous duodenal polyp, a different entity: report of a case and review of the literature","volume":"23","author":"Nebril","year":"1993","journal-title":"Surg Today"},{"key":"R22-11-20210131","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00384-002-0411-x","article-title":"Course and follow-up of solitary Peutz-Jeghers polyps: a case series","volume":"18","author":"Oncel","year":"2003","journal-title":"Int J Colorectal Dis"},{"key":"R23-11-20210131","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1002\/1097-0142(19820301)49:5<971::AID-CNCR2820490522>3.0.CO;2-1","article-title":"Adenomatous and carcinomatous changes in hamartomatous polyps of the small intestine (Peutz-Jeghers syndrome): report of a case and review of the literature","volume":"49","author":"Perzin","year":"1982","journal-title":"Cancer"},{"key":"R24-11-20210131","first-page":"134","article-title":"Very remarkable case of familial polyposis of mucous membrane of intestinal tract and nasopharynx accompanied by peculiar pigmentations of skin and mucous membrane","volume":"10","author":"Peutz","year":"1921","journal-title":"Nederl naandschr v geneesk"},{"key":"R25-11-20210131","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/hmg\/8.1.45","article-title":"Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer","volume":"8","author":"Ylikorkala","year":"1999","journal-title":"Hum Mol Genet"},{"key":"R26-11-20210131","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1002\/1097-0142(19821001)50:7<1384::AID-CNCR2820500726>3.0.CO;2-5","article-title":"Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix","volume":"50","author":"Young","year":"1982","journal-title":"Cancer"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/PAS.0b013e3180339944","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:50:06Z","timestamp":1786035006000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000478-200708000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e3180339944","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}