{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:27:22Z","timestamp":1791563242456,"version":"4.3.4"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1097\/pas.0b013e31815b212b","type":"journal-article","created":{"date-parts":[[2008,3,27]],"date-time":"2008-03-27T03:42:58Z","timestamp":1206589378000},"page":"615-619","source":"Crossref","is-referenced-by-count":174,"title":["Immunohistochemical Expression of Langerin in Langerhans Cell Histiocytosis and Non-Langerhans Cell Histiocytic Disorders"],"prefix":"10.1097","volume":"32","author":[{"given":"Sean K.","family":"Lau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiguo G.","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence M.","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"5","key":"R1-15-20210131","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/0190-9622(92)70120-5","article-title":"CD1 (OKT6)-positive juvenile xanthogranuloma. OKT6 is not specific for Langerhans cell histiocytosis (histiocytosis X)","volume":"26","author":"Andersen","year":"1992","journal-title":"J Am Acad Dermatol"},{"key":"R2-15-20210131","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/jid.1961.80","article-title":"An electron microscope study of basal melanocytes and high-level clear cells (Langerhans cells) in vitiligo","volume":"37","author":"Birbeck","year":"1961","journal-title":"J Invest Dermatol"},{"key":"R3-15-20210131","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s10024-004-3027-z","article-title":"Langerin (CD207) staining in normal pediatric tissues, reactive lymph nodes, and childhood histiocytic disorders","volume":"7","author":"Chikwava","year":"2004","journal-title":"Pediatr Dev Pathol"},{"key":"R4-15-20210131","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0046-8177(92)90403-P","article-title":"Deep juvenile xanthogranuloma: a lesion related to dermal indeterminate cells","volume":"23","author":"de Graaf","year":"1992","journal-title":"Hum Pathol"},{"key":"R5-15-20210131","first-page":"21","article-title":"Coexpression of CD1a, langerin and Birbeck's granules in Langerhans cell histiocytoses (LCH) in children: ultrastructural and immunocytochemical studies","volume":"45","author":"Dziegiel","year":"2007","journal-title":"Folia Histochem Cytobiol"},{"key":"R6-15-20210131","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/(SICI)1096-911X(199709)29:3<157::AID-MPO1>3.0.CO;2-C","article-title":"Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic\/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society","volume":"29","author":"Favara","year":"1997","journal-title":"Med Pediatr Oncol"},{"key":"R7-15-20210131","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1073\/pnas.78.4.2541","article-title":"Reactivity of Langerhans cells with hybridoma antibody","volume":"78","author":"Fithian","year":"1981","journal-title":"Proc Natl Acad Sci USA"},{"key":"R8-15-20210131","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.0303-6987.2006.00453.x","article-title":"Histiocytic sarcoma with secondary involvement of the skin and expression of CD1a: evidence of indeterminate cell differentiation?","volume":"33","author":"Frater","year":"2006","journal-title":"J Cutan Pathol"},{"key":"R9-15-20210131","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1182\/blood.V97.5.1241","article-title":"Differentiation of Langerhans cells in Langerhans cell histiocytosis","volume":"97","author":"Geissmann","year":"2001","journal-title":"Blood"},{"key":"R10-15-20210131","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1084\/jem.20020018","article-title":"Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin","volume":"196","author":"Geissmann","year":"2002","journal-title":"J Exp Med"},{"key":"R11-15-20210131","first-page":"293","article-title":"Langerhans cells","volume":"23","author":"Hammar","year":"1988","journal-title":"Pathol Annu"},{"key":"R12-15-20210131","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/01.pas.0000131541.95394.23","article-title":"Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy","volume":"28","author":"Hornick","year":"2004","journal-title":"Am J Surg Pathol"},{"key":"R13-15-20210131","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1172\/JCI200419655","article-title":"Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells","volume":"113","author":"Hunger","year":"2004","journal-title":"J Clin Invest"},{"key":"R14-15-20210131","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1046\/j.1365-2133.2002.04994.x","article-title":"Dendritic cells and apoptosis in mycosis fungoides","volume":"147","author":"Luftl","year":"2002","journal-title":"Br J Dermatol"},{"key":"R15-15-20210131","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1091\/mbc.01-06-0300","article-title":"Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates","volume":"13","author":"Mc Dermott","year":"2002","journal-title":"Mol Biol Cell"},{"key":"R16-15-20210131","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1365-2141.1995.tb05313.x","article-title":"Evidence for a polyclonal nature of the cell infiltrate in sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease)","volume":"91","author":"Paulli","year":"1995","journal-title":"Br J Haematol"},{"key":"R17-15-20210131","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1023\/A:1021793530802","article-title":"Analysis of binding of mannosides in relation to Langerin (CD207) in Langerhans cells of normal and transformed epithelia","volume":"34","author":"Plzak","year":"2002","journal-title":"Histochem J"},{"key":"R18-15-20210131","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0003-9969(02)00173-5","article-title":"Langerin+ versus CD1a+Langerhans cells in human gingival tissue: a comparative and quantitative immunohistochemical study","volume":"48","author":"Seguier","year":"2003","journal-title":"Arch Oral Biol"},{"key":"R19-15-20210131","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1097\/01.pas.0000249443.82971.bb","article-title":"Immunohistochemical analysis of langerin in langerhans cell histiocytosis and pulmonary inflammatory and infectious diseases","volume":"31","author":"Sholl","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R20-15-20210131","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00428-003-0952-6","article-title":"Diagnostic relevance of Langerin detection in cells from bronchoalveolar lavage of patients with pulmonary Langerhans cell histiocytosis, sarcoidosis and idiopathic pulmonary fibrosis","volume":"444","author":"Smetana","year":"2004","journal-title":"Virchows Arch"},{"key":"R21-15-20210131","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1002\/(SICI)1521-4141(199909)29:09<2695::AID-IMMU2695>3.0.CO;2-Q","article-title":"The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface","volume":"29","author":"Valladeau","year":"1999","journal-title":"Eur J Immunol"},{"key":"R22-15-20210131","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1074-7613(00)80160-0","article-title":"Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules","volume":"12","author":"Valladeau","year":"2000","journal-title":"Immunity"},{"key":"R23-15-20210131","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1385\/IR:28:2:93","article-title":"Langerin\/CD207 sheds light on formation of Birbeck granules and their possible function in Langerhans cells","volume":"28","author":"Valladeau","year":"2003","journal-title":"Immunol Res"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00000478-200804000-00015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:54:17Z","timestamp":1786035257000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000478-200804000-00015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/pas.0b013e31815b212b","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}